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Propecia or Spiro - which do you think is more effective? (Propecia, Finasteride for Women)

posted by V, 20.10.2007, 15:42

Ok...this is soley my opinion and what I have read and learned from several HL boards. If it were me, I would go with 2.5 mg of finasteride. Women can even take up to 5 mg with no harsh side effects.

I know spiro and flutamide can really help, and CAN in some instances help those with normal T levels, but I still think fin or avodart is the better choice.

Here's a study (kind of vagaue I know) but it makes sense:

Effect of finasteride 5 mg (Proscar) on acne and alopecia in female patients with normal serum levels of free testosterone.Gynecol Endocrinol. 2007 Mar;23(3):142-5. Kohler C, Tschumi K, Bodmer C, Schneiter M, Birkhaeuser M.
Division of Gynaecological Endocrinology and Reproductive Medicine, Department Ob/Gyn, University of Berne. Berne. Switzerland.
In some women with acne or alopecia who have normal serum levels of free testosterone, no clinical improvement can be reached by the classical treatment with antiandrogens, isotretinoids or corticosteroids. Our hypothesis is that some of these women have an excessive activity of the enzyme 5alpha-reductase. We evaluated the subjective benefit of the treatment with finasteride (5 mg/day) in women with normal serum levels of free testosterone suffering from acne or alopecia. This was a retrospective study evaluating a questionnaire filled out by 12 patients, six of whom had acne and six of whom had alopecia. Nine of the 12 patients benefited from the finasteride treatment, their symptoms decreased significantly and they felt better psychologically than before the administration of finasteride. The other three patients did not benefit at all from finasteride and reported no change in the extent of the acne or alopecia. Treatment was generally well tolerated, only a few adverse effects were noted. Conclusions. Nine of the 12 patients benefited from the finasteride treatment. This supports our hypothesis of an excessive activity of 5alpha-reductase enzyme in peripheral tissue in these patients. The fact that three of the patients did not realize any change in their symptom severity implies that there must also be other pathways in the genesis of acne and alopecia in women with normal levels of free testosterone.

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