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bunnyheather...flutamide vs other anti-androgens (Androgenetic Alopcia (AGA) Female Pattern)

posted by sky77, 30.01.2008, 22:18

I have been taking cyproterone and spiro since stopping birth control 3 years ago and during this whole time I have not had a natural period without taking hormones. I seem to have problems with taking estrogen i.e acne, worse hairloss, nausea (both synthetic and bio-identical). My endo tried to get my ovaries to work via all sorts of hormone medications with no luck ( I just turned 30 so way to young to have no estrogen in the body).

I started taking some form of estrogen regularly about 14 months ago and my hair loss and skin got much much worse which totally didn't make sense because I was taking an extremely high dose of cyproterone (200mg) and spiro(100-200mg). My endo and I tried all these different combos (higher estrogen, lower estrogen, different type of estrogen, lowering the anti-androgens) but nothing worked - during this time all my regrowth came in as miniturized hairs and I now have 25% of my original hair density left. For some reason my body just doesn't like estrogen with cypro or spiro.

So after some research, I told my endo I wanted to try flutamide because for some women, taking cypro and spiro can stop the ovaries from working (both of them have progesterone activity) and obviously taking an external form of estrogen is not working for me... I went to my appointment with printouts of information on flutamide (studies have shown that flutamide with metformin have helped some women to get back their menstrual cycles) and my endo agreed to let me try flutamide for 6 months as long as I get my liver checked regularly.

I have been on flutamide for 6 days. The week before flutamide my average hair loss was 100-150 a day. Yesterday my total hair loss was 77 and today it's on track for being somewhere between 80-90. My shower has gone from 100/130 to 63/65 in the last two days... I have stopped all the other anti-androgens and all I am taking is flutamide and metformin.

I know it is still early but I am hopeful this is going to work. My hair loss has gone from mainly terminal hair during shower/blowdrying to more miniturized hairs which I take is a good sign. This is my last resort - there are studies that flutamide works better than both spiro and cyproterone... hopefully it will work for me...

During my 3 years on cypro and spiro my hair never stopped falling out but I did have regrowth... but my hair was still thinning just slowly.

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