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Question about proscar / propecia (PCOS & Hair Loss)

posted by HairSite Admin, 09.05.2008, 22:15

What 'V' says is true -

Int J Fertil Womens Med. 1998 Mar-Apr;43(2):91-7

Androgens and women's health

Androgenic disorders are those conditions in women characterized by excessive androgen action. They are the most common endocrinopathy of women, affecting from 10% to 20%. Signs are: persistent acne, hirsutism and androgenic alopecia, which is the female equivalent of male pattern baldness. A subgroup, those traditionally labeled as having polycystic ovary syndrome (PCOS), additionally have anovulation, as well as menstrual abnormalities and, often, obesity. Although women with androgenic disorders usually present themselves for help with the skin or menstrual changes, there are other important implications regarding their health. Women with PCOS have varying degrees of insulin resistance, and an increased incidence of Type II diabetes mellitus, as well as unfavorable lipid patterns. The presence of these risk factors is suggested by upper segment obesity, darkening of the skin, and the other skin changes that make up acanthosis nigricans. Diagnosis involves measurement of circulating androgens (of which free testosterone is most important), together with prolactin and FSH when menstrual dysfunction is present.
Many women with androgenic skin changes have normal serum androgen levels, suggesting increased end organ sensitivity to androgens.
Others have hyperandrogenism (of ovarian or adrenal origin). Treatment is usually successful in controlling acne, reducing hirsutism and stabilizing, or partially reversing, androgenic alopecia. Pharmacological approaches involve suppressing androgen levels, for example, the use of an appropriate oral contraceptive, or antagonizing androgen action with several medications that have this activity. Unfortunately, most women with androgenic disorders are frustrated in their efforts to obtain medical help. Understanding androgenic disorders will enable the physician to significantly help the majority of women with these conditions.






» There is something I just don't understand about proscar / propecia. If
» women naturally have much less testosterone than men, and therefore would
» produce less DHT than men - why do women need a higher dose of proscar? It
» doesn't make sense to me. Any thoughts?
»
» Post reply

»
» It's not that we have so much less, eeven though we do, it's that we have
» such a sensitivity to the small amount we do have so it takes even more to
» overcome that sensitivity.

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