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Diagnostic criteria for PCOS (PCOS & Hair Loss)
Diagnostic Criteria in Polycystic Ovary Syndrome (PCOS)
Revised diagnostic criteria of PCOS -1999 criteria (both 1 and 2)
1. Chronic anovulation
2. Clinical and/or biochemical signs of hyperandrogenism, and exclusion of other aetiologies
Revised 2003 criteria (2 out of 3)
1. Oligo- and/or anovulation
2. Clinical and/or biochemical signs of hyperandrogenism
3. Polycystic ovaries
and exclusion of other aetiologies (congenital adrenal hyperplasias, androgen-secreting tumours, Cushing’s syndrome)
Other Proposed Diagnostic Criteria in Polycystic Ovary Syndrome
1. Inappropriate gonadotropin secretion
a)Elevated LH-to-FSH ratio
b)Abnormal response to GnRH agonist testing
2. Hyperandrogenism
a)Hirsutism, androgenic alopecia, acne
b)Hyperandrogenemia
I.Total testosterone
II.Free testosterone (free androgen index, etc.)
3.Ovarian appearance
a) Polycystic-appearing ovaries
b)Increased (stromal) size
4.Insulin resistance
a)Acanthosis nigricans
b)Fasting measures of insulin/glucose
c)Oral glucose tolerance test
d)Dynamic tests of insulin sensitivity
I.Euglycemic clamp
II.Frequently sampled intravenous glucose tolerance test
5.Chronic anovulation
a)Self-reported history
b)Tests of ovulatory function
I.Basal body temperature charting
II.Urinary LH testing
III.Serum progesterone measurement
IV.Endometrial biopsy
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Complete thread:
- Diagnostic criteria for PCOS - HairSite Admin, 09.05.2008, 22:31