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Lack of efficacy of finasteride in postmenopausal women with androgenetic alopec (Androgenetic Alopcia (AGA) Female Pattern)
» Lack of efficacy of finasteride in postmenopausal women with
» androgenetic alopecia.
»
» J Am Acad Dermatol. 2000 Nov;43(5 Pt 1):768-76
»
» BACKGROUND:
» Finasteride, an inhibitor of type 2 5alpha-reductase, decreases serum and
» scalp dihydrotestosterone (DHT) by inhibiting conversion of testosterone to
» DHT and has been shown to be effective in men with androgenetic alopecia
» (AGA). The effects of finasteride in women with AGA have not been
» evaluated.
»
» OBJECTIVE:
» The purpose of this study was to evaluate the efficacy of finasteride in
» postmenopausal women with AGA.
»
» METHODS:
» In this 1-year, double-blind, placebo-controlled, randomized, multicenter
» trial, 137 postmenopausal women (41-60 years of age) with AGA received
» finasteride 1 mg/day or placebo. Efficacy was evaluated by scalp hair
» counts, patient and investigator assessments, assessment of global
» photographs by a blinded expert panel, and histologic analysis of scalp
» biopsy specimens.
»
» RESULTS:
» After 1 year of therapy, there was no significant difference in the change
» in hair count between the finasteride and placebo groups. Both treatment
» groups had significant decreases in hair count in the frontal/parietal
» (anterior/mid) scalp during the 1-year study period. Similarly, patient,
» investigator, and photographic assessments as well as scalp biopsy analysis
» did not demonstrate any improvement in slowing hair thinning, increasing
» hair growth, or improving the appearance of the hair in finasteride-treated
» subjects compared with the placebo group. Finasteride was generally well
» tolerated.
»
» CONCLUSION:
» In postmenopausal women with AGA, finasteride 1 mg/day taken for 12 months
» did not not increase hair growth or slow the progression of hair thinning.
WIll you PLEASE post a study on women taking birth control AND finasteride together...?? ANd PRE menopausal? Thanks.
Complete thread:
- Lack of efficacy of finasteride in postmenopausal women with androgenetic alopec
- HairSite Admin, 29.06.2008, 01:55
- Lack of efficacy of finasteride in postmenopausal women with androgenetic alopec - bunnyheather, 30.06.2008, 13:38
- Lack of efficacy of finasteride in postmenopausal women with androgenetic alopec - Marjie, 01.07.2008, 12:46
- Lack of efficacy of finasteride in postmenopausal women with androgenetic alopec - HairSite Admin, 01.08.2008, 11:43
- Lack of efficacy of finasteride in postmenopausal women with androgenetic alopec
- penny1, 01.08.2008, 13:18
- Lack of efficacy of finasteride in postmenopausal women with androgenetic alopec - mauri, 02.08.2008, 12:28
- Lack of efficacy of finasteride in postmenopausal women with androgenetic alopec - bunnyheather, 30.06.2008, 13:38