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TOPICAL HAIR LOSS AGENTS

Most topical hair loss agents can be broken down into 4 main categories.

  1. DHT Antagonist - Products that inhibit 5-alpha reductase, an enzyme that converts testosterone to DHT. DHT stands for dehydrotestosterone which many believe is the main cause for androgenetic alopecia. 
     

  2. Hair Growth Stimulant - Products that many believe will stimulate existing hair growth. Some products work by enhancing cells and vascular proliferation while others may prolong the anagen phase of hair cycle. 
     

  3. Anti-inflammatory - Inflammation such as seborrhoeic dermatitis is one of the most common causes for hair loss. Scalp inflammation can also be caused by long term use of propylene glycol and alcohol based products such as topical minoxidil. 
     

  4. Androgen Receptor Blocker - These compounds block the pathway of androgens by competitively binding to androgen receptor sites in cells and tissues and thereby inhibiting the harmful effects of androgens on hair cells. Most of these products are experimental in nature.

DHT Antagonist
Products that inhibit 5-alpha reductase, an enzyme that converts testosterone to DHT. DHT stands for dehydrotestosterone which many believe is the main cause for androgenetic alopecia. 

Crinagen (5% azelaic acid + zinc + B6 + Grape Seed Extract et al) - azelaic acid can effect up to 90% DHT inhibition according to a study reported in the British Journal of Dermatology.
Vendor: Dr. Razack

Azelaic Acid  - some studies suggested that this agent can be highly effective in inhibiting DHT on skin.
Vendor:
HairMedics | Dr. Razack

Hair Growth Stimulant
Products that many believe will stimulate existing hair growth. Some products work by enhancing cells and vascular proliferation while others may prolong the anagen phase of hair cycle. 

Retin A  - Studies have shown that Retin-A alone can result in moderate hair growth in some patients. Retin-A is mostly used in conjunction with minoxidil as this compound seems to be able to enhance the penetration and absorption of minoxidil by altering the follicular epithelium.
Vendor:
HairMedics | Dr. Klein

Minoxidil Basic 2% - 6%  - #1 selling hair loss product in the world. The only topical lotion approved by the FDA for treating hair loss.
Vendor:
HairMedics | Dr. Klein

Super Strength Minoxidil 12%  - #1 selling hair loss product in the world now available in high potency concentration of 12%.
Vendor:
Dr. Klein

Propylene Glycol Free Minoxidil - #1 selling hair loss product in the world now available in a propylene glycol free formula for people with sensitive scalp. 
Vendor:
Dr. Klein

Minoxidil with Corticosteroid - #1 selling hair loss product in the world now available with small concentration of corticosteroid, an anti-itch, anti-inflammatory agent that  can alleviate scalp irritations such as scalp itch, flakes and redness commonly associated with topical minoxidil.
Vendor:
Dr. Klein

Minoxidil-Retin-A combo - Studies have shown that the potency and efficacy of minoxidil can be enhanced when used in conjunction with Retin-A.
Vendor:
HairMedics | Dr. Klein

Minoxidil-Finasteride combo - Probably the most synergistically ideal solution for hairloss. Minoxidil works as a hair regrowth stimulant while 5-alpha reductase inhibitor finasteride is known to halt further hairloss. Targeting hairloss at both angles.
Vendor:
HairMedics 

Minoxidil-Azelaic Acid combo - DHT is commonly suggested to be the main cause for hairloss. Studies have shown that azelaic acid may function as an DHT inhibitor and may work synergistically together with minoxidil to stimulate hair regrowth while halting further hairloss. 
Vendor:
HairMedics 

Minoxidil with Azelaic Acid, Zinc, B6 & Grape Seed Extract combo - a multi-modal approach to treating hairloss by combining minoxidil and azelaic acid with various supplements that are known to be beneficial for stimulating hair growth while reducing hairloss. 
Vendor:
HairMedics 

Minoxidil with Nicotinate - Nicotinate is a blood vessels dilator. This additive when used in conjunction with minoxidil may enhance the penetration and potency of minoxidil. 
Vendor:
HairMedics 

Minoxidil with Progesterone - Progesterone is a female hormone added in very small quantities to neutralize the local action of DHT. Not a lot of studies on the effect of topical progesterone on hairloss but some people think this may be beneficial for women pattern baldness. 
Vendor:
HairMedics 

Anti-inflammatory
Inflammation such as seborrhoeic dermatitis is one of the most common causes for hair loss. Scalp inflammation can also be caused by long term use of propylene glycol and alcohol based products such as topical minoxidil. 

Emu Oil - nature's anti-inflammatory agent for hair, skin and scalp with potential for enhancing hair growth.
Vendor:
HairMedics

Nizoral Shampoo - 2% ketoconazole is the world's #1 prescribed compound for dandruff and other scalp inflammatory conditions.
Vendor:
HairMedics

Betnovate - Betamethasone Valerate 0.1%. Indicated for psoriasis and seborrhoeic dermatitis of the scalp..
Vendor:
HairMedics

Dermovate - Clobetasol propionate 0.05%. Indicated for severe dermatitis of the scalp.
Vendor:
HairMedics

Diprosalic - a unique formula that combines two effective agents for scalp dermatitis and psoriasis. 0.05% Bethamethasone and 2% salicylic acid. Indicated for the relief of the inflammatory reactions of the scalp in seborrhoea and psoriasis.
Vendor:
HairMedics

Tea Tree Oil - Anti-inflammatory, anti-bacterial topical agent. Gentle for the scalp and yet strong enough to kill ringworm, head lice and even stubborn bacteria such as staphylococcus.   
Vendor: Dr. Razack 

Androgen Receptor Blocker
These compounds block the pathway of androgens by competitively binding to androgen receptor sites in cells and tissues and thereby inhibiting the harmful effects of androgens on hair cells. Most of these products are experimental in nature.

Fluridil/ Eucapil - a new topical antiandrogen designed specifically for androgenetic alopecia that works by suppressing the androgen receptors in the skin.
Vendor:
Inter-Pharma

Spironolactone - Recent studies have shown that topical spironolactone can act as an antiandrogen in human sebaceous glands, competing with DHT receptors and producing a decrease of labeled DHT.

Cyproterone Acetate - Recent studies have shown that topically applied cyproterone acetate in combination with liposomes are as effective as oral antiandrogen medication while reducing the risk of adverse effects. 


 
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Books on hair loss

Dermatologists
Hair salon listing
Hair salon furniture & equipment
Hair salon & beauty salon supplies
Books: hair care & styling tips
Wigs & hair extensions
Consumer Alerts

subscribe to our newsletter

hair loss products

Recommended Doctors

 
Dr. Ray Woods
Sydney, Australia
 
Dr. Angela Woods Campbell
Sydney, Australia

 
Drs. Hasson & Wong
Vancouver, Canada
 
Dr. John Cole
Atlanta, Belgium, New York

 
Dr. Alan Bauman
Boca Raton, Florida

 
Dr. Alvi Armani
Toronto, Dubai, London

 
Dr. Robert Jones
Toronto, Canada

 
Dr. Arvind Poswal
New Delhi, India

 
Dr. Sanusi Umar
California
 
 
 HDC Medical Trichology Center
Cyprus, London, Europe

Instant Hair Thickening Fibers
Dr. Robert Jones

 

no drugs | no surgery | thickens in seconds | for both men and women | Free of charge
click here for details

Directory for Everything HAIR!

 
Hair Loss Articles & Videos
Hair replacement systems
Hair transplant:featured doctors
Newsletter
Knowledge Base
Hair transplant doctors worldwide
Books on hair loss

Dermatologists
Hair salon listing
Hair salon furniture & equipment
Hair salon & beauty salon supplies
Books: hair care & styling tips
Wigs & hair extensions
Consumer Alerts

subscribe to our newsletter

hair loss products

 

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