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LaserComb Laser Photo Therapy
Mechanism of Action Hypothesis
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The HairMax LaserComb is cleared for marketing by the FDA for The Promotion of
Hair Growth in males with Androgenetic Alopecia who have Norwood Hamilton
Classifications of IIa-V and Fitzpatrick Skin Types I to IV
Although hundreds of clinical papers have
been written about the positive attributes of low level laser therapy, the
exact mechanism of action of the HairMax is still under clinical
investigation. Users and clinical trial subjects have observed hair growth
and hair cycle changes that are related to HairMax’s Laser PhotoTherapy
properties. Therefore, the following hypotheses have been formed that
attempt to explain the method of action of the HairMax.
The laser light of the HairMax penetrates the scalp and hair follicles in a
consistent manner via its patented hair parting teeth system. The teeth of
the HairMax part the hair to allow for precision delivery of laser light to
all areas of the scalp and an unobstructed path to the hair follicle.
Without the patented hair parting teeth, as much as 90% of the laser light
energy can be blocked by the hair. Remember, the treatment is most effective
when the laser path is unobstructed.
Anagen Induction and Accelerated Hair
Growth
It is hypothesized that Laser PhotoTherapy applied to the scalp directly
affects the hair follicle by Photo-Bio Stimulation leading to Anagen
Induction. This process, in which the laser light bathes the scalp and
follicular cells, causes an increase in ATP and Keratin Production and the
stimulation of hair growth. Users routinely report faster hair growth during
treatment with the HairMax which may be attributable to the above mentioned
hypothesis.
Cell Proliferation of the Epithelia
Associated with Terminalization of Hair
It is further hypothesized that the laser light of the HairMax causes cell
proliferation in the epithelia of the hair follicle marked by thicker hair
growth and an increase in shedding of Catagen hairs at the onset of
treatment. Since the dermal papilla consists of certain fibroblasts and
specialized matrix cells at the base of the hair follicle, the laser light
of the HairMax apparently interacts with these cells causing cell
proliferation. In support of this assumption are consistent user reports of
shedding at the onset of treatment and clinical trial results demonstrating
distinct terminalization of hairs formerly in the vellus phase.
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