Hair loss
treatment: Topical Formula - archives
Oct 03
- Oct 09, 2005
Topical
/ Reference – RU 58841 RUM-myristate
discussion
“Results: While receptor binding experiments proved the almost
complete loss of binding to the androgen receptor by ester formation,
RUM is rapidly metabolised to the potent antiandrogen RU 58841 by
cultured human skin cells. Cellular viability was not impaired.”
Click here for details
Oct 03 - Oct 09, 2005
Topical – Fluridil Updates.
“3.5 months and still going. Im not at a point yet where i can
access its efficacy, but i can say that it doesnt cause me any
problems other than slight dryness of my hair, and i believe that only
became a problem when i started applying it in the morning right after
my hair became fully dry out of the shower, and let it sit in all day
until the next morning. Otherwise it somehow makes my hair look even
better after i apply it. I would say with confidence my hair line has
continued to subtly slip back despite its application, but thats
pretty expected with any hair loss product.”
Click here for details
Oct 03
- Oct 09, 2005
Topical
– ScalpMed discussion.
“I figured minox was their main ingredient because the commercial
says it's main ingredient is the most powerful FDA approved ingredient
to regrow hair.”
Click here for details
Sep 26 - Oct 02, 2005
Topical / Reference – Liposomes vs traditional delivery
mechanisms.
“A liposome has the same basic structure as a cell's membrane(fatty
acids). This means that once in touch with a membrane it
"melts" with it introducing its content inside the cell. So
the medicine is not wasted but gets cleanly inside the cell and thus
is a much better approach to just put in the skin surface and hope it
will get inside somehow. In addition as it doesn't contain anything
that can irritate the skin it has more benefits over alcohol-based
products.”
Click here for details
Sep 26 - Oct 02, 2005
Topical / Reference – Modulation of hair growth with small
molecule agonists of the hedgehog signaling pathway.
“These results suggest that the topical application of Hh-agonist
could be effective in treating conditions of decreased proliferation
and aberrant follicular cycling in the scalp including androgenetic
alopecia (pattern hair loss).”
Click here for details
Sep 19 - Sep 25, 2005
Topical – Curis and Procter & Gamble Enter into R&D
Agreement for Hair Growth Program.
“To date, Curis scientists have demonstrated that small molecule
Hedgehog
agonists can induce hair growth in pre-clinical models.
Under the terms of the agreement, the Company has granted P&G an
exclusive, worldwide royalty-bearing license for the non-systemic,
dermatological use of Curis' Hedgehog agonist technology, via topical
administration.”
Click here for details
Sep 19 -
Sep 25, 2005
Topical – Proctor & Gamble gambles on
Curis Hedgehog Study
Procter & Gamble Pharmaceuticals has entered
into a research and development agreement with Curis, Inc. to study
and develop possible treatments for hair growth regulation using Curis'
Hedgehog agonist technology.
Click here for details
Sep 12
- Sep 18, 2005
Topical
– Genistil-R updates
“I have been using the normal Genistil for 2 months once a day on
the frontal hairline. My impression is that it is not as effective as
a androgen receptor (AR) blocker like spironolactone.”
Click here for details
Sep 12 - Sep 18, 2005
Topical – Fluridil 2 month update, positive feedback
” Eucapil has definately helped my hairline and all over. I've been
using it about 2mo. With Avo. my hair was barely hanging on after 9
mo. but with Eucapil it actually started growing making it necessary
for me to even get a hair cut in the near future.”
Click here for details
Aug 29 - Sep 04, 2005
Topical / Reference – Curis Hedgehog Signaling
Hedgehog Agonists Modulate Hair Growth; Preclinical Data Published in
The Journal of Investigational Dermatology
Click here for details
Aug 29 - Sep 04, 2005
Topical – Alpecin (coffee) testimonials
I have been using Alpecin Shampoo and After Shampoo Liquid for about
2.5 months. I was having a pretty good shed and it stopped it
immediately. Without question it has made my vellus hair at the
temple/hairline go termial. I have tried everything to make these
hairs go terminal and I think this is finally doing the trick. I'm not
sure about any regrowth yet because its very difficult to tell if the
terminal hairs are coming in are all from the vellus I had or are
simply new. I am finally on my way from a NW 2 to a NW 1. This is
terrific news!
Click here for details
Aug 29 - Sep 04, 2005
Topical – Copper Peptide discussion.
“There is a lot of study behing Dr. Pickarts work...it was once
(about 10 years ago) though to be the cure, or at least blow minox
away, and the early studies did, granted what was released (trichomin)
was alot weaker then what was to go to FDA trials, but there is solid
science behind this...it is an SOD with major backing.”
Click here for details
Aug 29 -
Sep 04, 2005
Topical – Hedgehog Agonists Modulate Hair
Growth; Preclinical Data Published in The Journal of Investigational
Dermatology
This study also demonstrated that the Hedgehog
agonist is active in human scalp in vitro as measured by Hedgehog
pathway gene expression. The results suggest that topical application
of a Hedgehog agonist could be effective in treating hair loss
conditions, including male and female pattern hair loss.
Click here for details
Aug 22 - Aug 28, 2005
Topical – Scalp Scripts Coenzyme 12% Hair Therapy
“Scientifically proven to stimulate new hair growth due in large
part to its high percentage of panthenol and cysteine, a keratin
protein which is in and of itself the basic protein found in human
hair. This highly concentrated preparation for home treatments
contains biotin, Dexpanthenol, two vitamins, cysteine, cystine,
methionine, and amino acids which are found in the hair shaft.”
Click here for details
Aug 22 - Aug 28, 2005
Topical – Shampoo discussion.
A lengthy discussion about shampoos, especially NANO shampoo.
Click
here for details
Aug 22 - Aug 28, 2005
Topical – Fluridil vs Revivogen discussion.
“I've been using eucapil for 2 months, and I am generally pleased,
however I don't read of too many people using it, rather, I read about
revivogen, should I switch?”
Click here for details
Aug 08 - Aug 14, 2005
Topical / Reference – TB4 related licensing agreement?
“Panacea Biotec in-licenses novel technology from NIH for hair
growth.”
”A peptide based technology for alopecia management from the
National Institute of Health, USA. The patent protected technology for
actin- binding peptide(s)/poly peptide(s) stimulates hair growth and
regenerates lost hair follicles. The ability of hair follicles to
constantly renew is ensured by the presence of the multipotent stem
cell. This peptide(s) appears to stimulate multipotent stem cells at
the `bulge region.”
Click here for details
Aug 08
- Aug 14, 2005
Topical
– Minoxidil alternative
“Maybe procyanidins..like those in Poly-Gro and even Revivogen..??
You could be allergic to pg or something else, even the alcohol. http://www.elsomresearch.com makes theirs w/out those two ingredients. See their
Formulator for gse and apple peel extract for the pro's. Also Rooibos
is another good alternative IMO. “
Click here for details
Aug 01 - Aug 07, 2005
Topical – NanoAdeno Discussions.
“It is a cream. The cream has darkened over the last thirty days, so
a week ago, I started to store it in the refridgerator. The scent of
licorice, once so strong when I first opened the bottle, is now much
weaker. The product is soothing to the skin. It disappears into the
scalp (or into the hair) within about 45 minutes, although the hair
itself looks like it needs shampooing later.”
Click here for details
Aug 01 - Aug 07, 2005
Topical – Minoxidil, self compounded formula worth a try?
“One bottle of Rogaine 5% contains 3000 milligrams (3 grams) of pure
minoxidil. Loniten (minoxidil) tablets are usually sold in 10
milligram (active ingredient) tablets. It takes 3000/10 = 300 Loniten
(minoxidil) tablets to make a bottle of 5% solution.”
Click here for details
Aug 01 - Aug 07, 2005
Topical – Follicare discussions.
“I sent Follicare my testimonial for those of you who have followed
my story . They called me and asked me to read them my testimony over
the phone, the gentleman said they will record 5 and 10 second sound
bites for my testimony to play on the radio ads. They were very
impressed with the before and after pics i sent and will use them on
their website.”
Click here for details
Aug 01 - Aug 07, 2005
Topical / Drugs – Rogaine & Propecia testimonials.
“Rogaine 5% & Propecia for only 2 months = RESULTS, but stopped
Propecia, now start back up?”
Click here for details
Jul 25 - Jul 31, 2005
Topical – 5-aminolevulinic acid (ALA), new product from Cosmo Oil
in Japan
Cosmo Oil Co., Ltd. and Dr. Yoshiyasu Ito (Part-time lecturer at
Department of Dermatology, National Defense Medical College, and
Director of Daikanyama Derm-Plastic Clinic), announces that they have
agreed to jointly pursue commercialization and business development of
a hair growth stimulant containing 5-aminolevulinic acid (ALA) as an
active ingredient.
Click here for details
Jul 25 - Jul 31, 2005
Topical – Minoxidil opinions.
Minoxidil was and is a high blood pressure medication (in pill form
called Loniten). Minoxidil was found to grow hair only after it had
been on the market as a high blood pressure medication for many years.
Very little of the minox applied TOPICALLY will be absorbed into the
bloodstream and it should have little, if any, systemic effects
(rapid, irregular heart rate, etc.). Minox does not interfere in any
way with DHT. Studies suggest that very little of the
topically-applied minoxidil actually penetrates the skin - even less
likely is penetration to the point of absorption into the bloodstream.
Click here for details
Jul 25 - Jul 31, 2005
Topical – Fluridil testimonials.
Right away I noticed a cosmetic improvement in my hair, in that it
appears to have some sort of cosmetic hair thickner, probably not
unlike any of the commecial products you can buy in any drugstore. I
got somehow the same results with Triaxon which I used for years. It
made my hair look and feel better, it made it look thicker and
healthier, but it did not "grow" hair, and so far the jury
is still out on eucapil.
Click here for details
Jul 18 - Jul 24, 2005
Topical / Reference - Minoxidil and Propylene Glycol Allergic
Study.
“All patients complained of increased pruritis and scaling of the
scalp. Three of them developed papules and vesicles on the scalp and
the forehead, 2 women presented with periorbital edema and in 2
patients ther dermatitis spread to the trunk. Patch testing resulted
in a delayed-type allergy to Regaine 5% and elucidated the specific
allergen involved in 7 patients.”
Click here for details
Jul 18 - Jul 24, 2005
Topical – Fluridil testimonials, Dr. Dut
Some of you may know that a 18months ago I withdrew my personal
backing of fin and dut because of side effect issues. I moved over to
Fluridil. I am now in the sad position to be withdrawing my
personal backing for this product too. My concerns are not with
efficacy, but with the issue of systemic absorption.
Click here for details
Jul 18
- Jul 24, 2005
Topical
– Fluridil Side Effects?
I have been using fluridil for the last 9months with decent results.
In the last 2 months i have also been experiencing numbness, muscular
twitching in my legs, arms and hands. I was thinking it is probably
some neurological disease starting but the neurologist said its a
neuropathy from something but does not know from what. Is there any
chance fluridil could be causing this?
Click here for details
Jul 11
- Jul 17, 2005
Topical
– Super Oxicell
ingredients
Active Ingredients:
Glutathione, SOD, Taurine, Cystine, Cysteine, Glutamic Acid, Glycine,
Boswellia, Green tea polyphenols, Vit. B6, Niacin, Vit. E, NAC, Sam-e,
Coq10, Alpha lipoic acid, Bayberry, Bitter Kola, Blue Gumtree,
Riboflavin, Ashwagandha root, NADH, FADH2, ATP, Zinc, Sodium Chloride,
Astragalus root, Juniper Berries, Brazillian Cress, Arnica, Fluoric
Acid, Olive, Sweet Chestnut, Agrimony, Willow, Aspen, Gorse, Holly,
Copper, Phosphorus, MAnganese, Selenium, Germanium.
Click here for details
Jul 11
- Jul 17, 2005
Topical
– Fred102 answers
questions regarding the EHRS conference.
Lengthy answers on questions about finasteride, procyanidin, Applepoly
etc.
Click here for details
Jul 11
- Jul 17, 2005
Topical
– Fluridil + Dutasteride
results
I use Dutasteride as well as Fluridil. I think that using those two
things is the best "one-two punch" we currently have to
fight DHT and other hairloss-causing androgens.
Click here for details
Jul 11 - Jul 17, 2005
Topical – Lion Develops Innovative Retardant for Male Hair Loss
Ingredients: Beta-glycyrrhetinate, piroctone olamine, inh- ibitory,
Click here for details
Jun 27
- Jul 03, 2005
Topical
– Minoxidil results leveling off.
After about 10 years of using Minoxidil, I dont seem to be getting any
return or even vellus coverage on the 2% during the day and 5% during
the night. When I first starting using it I got a good return - enough
to cover a bald spot! But no more. Has anyone else experienced this? -
and if so, are there any alternatives with a different kind of topical
that one of you gentlemen may have had success with?
Click here for details
Jun 27 - Jul 03, 2005
Topical – NanoAdeno, first impressions
“Nanoadeno comes in a small brown glass bottle, about the size of a
minoxidil bottle, containing 50 grams, which will last fifty days. It
cost about seventy dollars, including shipping. The contents are a
thick liquid, almost a cream, the color of Ivory dishwashing liquid.
The directions say you apply it when your hair is wet. Also they make
clear that this is a cosmetic product, not a drug intended to treat or
cure any disease.”
Click here for details
Jun 27 - Jul 03, 2005
Topical – Fluridil results.
“When fluridil breaks down in the body if it enters the blood
stream. It breaks down into trifluoroacetic acid and b34. The first
one is a hazadous substance, and I don’t know what b34 is. I have
used fluridil for about 8 months with good results. But after getting
gyno from propecia after 6 years of use and having to have surgery to
remove it. I think I will have to stop using fluridil. Dont know if it
can give you gyno but don’t want to take that chance.”
Click here for details
Jun 20 - Jun 26, 2005
Topical – Finasteride, topical formula.
“I've used 2 5mg Fincar (Proscar) pills mixed w/Minox. since March.
My results are good and encourging. I also take 1.25mg of Fincar
daily. I use this mix once/day some times twice, some times I forget
or don't have time to apply it. My hair is thicker and between my
thick hairs I have developed vellus hair that probably have always
been there.”
Click here for details
Jun 20
- Jun 26, 2005
Topical
– NanoAdeno, by Fred102
"We are running some accelerated stabilization testing on the
batch for
oxidation and physical stability and by Thursday evening we will
finish
the testing process. If you start taking orders Friday, we'll be able
to start
processing them Monday." So on Friday you can order nanoadeno
from http://www.nanoadeno.com”
Click here for details
Jun 20 - Jun 26, 2005
Topical – Remox results
“Remox II works greak in conjunction with a good anti-androgen. I've
been on and off it for about 2 years now. Hair starts to slowly
detoriate slowly woithout it for me. With it, I slowly gain ground.”
Click here for details
Jun 13 - Jun 19, 2005
Topical – Procede warning & testimonials.
“Procede contains thioglycolic acid - the main ingredient of the
hair remover Veet. Mostly used in perms. It will remove some weaker
hairs like Veet does and it will straighten stronger hairs.“
Click here for details
Jun 13 - Jun 19, 2005
Topical – Fluridil testimonials
I have used Eucapil (Fluridil) for 9 months now (3 times a supply of 3
boxes) and my conclusions thus far are:
- Halting of further loss
- Improving and thickening up of existing hair
- Filling up of the crown area that has started thinning a bit
- Growth of short hairs at the hairline, they are getting longer and
longer (which indicates that further loss has stopped)
- Growth of many vellus hair at the temple region
- No irritation at all
Click here for details
Jun 13
- Jun 19, 2005
Topical
– Revivogen testimonials.
“I have been using revivogen for over 9 month now and I am very
happy with the results. I honestly dont understand why there are so
few positive feed back regarding it (same about 17 a estradiol ). My
hair is much thicker due to it and it is the ONLY product that was
able to thicken vellus hair which I really gave hope before using
revivogen. It is a very effective product.”
Click here for details
Jun 06 - Jun 12, 2005
Topical – Scalp photos taken with 100x beauty scope.
Magnified scalp photos of Hogan38.
Click here for details
Jun 06 - Jun 12, 2005
Topical / Reference – Procyanidin B-2 is a TGF-B inhibitor.
“Procyanidin B-2 is a TGF-B inhibitor, similar to ellagic acid,
which
has been shown to have hair growth promoting activities in quantity.”
Click here for details
Jun 06 - Jun 12, 2005
Topical / Reference – Ursolic acid
Ursolic acid has medicinally action, both topically and internally.
Ursolic acid is used in many cosmetic preparations for its
anti-inflammatory, antitumor and antimicrobial properties. Ursolic
acid has antibacterial and antifungal activity.
Click
here for details
Jun 06 - Jun 12, 2005
Topical – Spiro lotion, home made.
Discussion about making a topical spiro formula.
Click here for details
Jun 06
- Jun 12, 2005
Topical
– Mesotherapy
“Mesotherapy is an effective treatment for the prevention of hair
loss. Mesotherapy is medicine that is injected directly into the pilar
cyst, which is very effective for treatment for hair loss. The
injections are made up of nutritive elements that accelerate cell
division of the hair roots and boost blood circulation around the hair’s
root, and an antiphlogistic agent, which dissolves inflammation around
the hair’s root.”
Click here for details
Jun 06 - Jun 12, 2005
Topical – Procede, Electronic Retailing Self-Regulation Program (“ERSP”)
report.
ERSP determined that the studies on ProCede submitted by Youth
Enhancement provided a reasonable basis for its core product
performance and safety claims but, based upon the omission of
comparative data in the case record, it was also recommended that the
marketer discontinue its comparative performance claims.
Click here for details
May 30
- Jun 05, 2005
Topical
– Minoxidil, initial
shed.
“The first 3 months I suffered a bit of shockloss but since then I
have lost very little hair. I was wondering how long does it usually
take to see any results?”
Click here for details
May 30 - Jun 05, 2005
Topical – Procede testimonials.
“I certainly don't see any hair regrowth after 48 hours (although
they claim you can). I didn't expect to. But I do have that
"stubble" feeling where I applied the product. Where the
skin was smooth, it is now a bit rough. It does feel like whisker
stubble, but I don't really see anything visible. Perhaps it just
changed the texture of the skin.”
Click here for details
May 30 - Jun 05, 2005
Topical – Proxiphen testimonials
I tried prescription proxiphen for a year and it didn't do anything.
Zippo. Nadda. Just money down the drain. That doesn't mean it won't
work for you or anybody else. That was my experience. I had much
better success with proscar.
Click here for details
May 30 - Jun 05, 2005
Topical – Fluridil but not shampooing ?
Fluridil seems worth considering but the not being able to shampoo
aspect totally kills it for me, but i wondered if anyone ignored that
with success?
Click here for details
May 30 - Jun 05, 2005
Topical / Drugs – Gunner’s testimonials and photos.
“I’ve been on Dut since Feb 21st and I am around the 3.5 month
mark of usage. I can honestly say that my hair has gotten worse since
starting this drug. Although I cannot be 100% sure, I feel this has a
lot to do with the Dut alone.”
Click here for details
May 30 - Jun 05, 2005
Topical – Bioscor’s testimonials
“There is a branch-serving store in Taiwan,which sells lots of
Bioscor products such as vitamin supplies,lotion,laser treatment and
so on..”
Click here for details
May 30 - Jun 05, 2005
Topical / Reference – Retinoic Acid induces Catagen by TFG-b2
upregulation in human hair follicles.
Retinoic acid can have adverse effects on human hair follicles. While
systemic intake of retinoic acid is able to induce telogen effluvium,
topical treatment of human scalp hair follicles with tretinoin may
also result in a prolonged anagen phase. Therefore, we have
investigated the influence of all-trans retinoic acid (RA) on the
growth of human hair follicles in culture.
Click here for details
May 30 - Jun 05, 2005
Topical – Kerasome testimonials.
“I’ve used it 2 times and really like it. It gives my hair more of
a thickness and body I havent had in years. My only complaint is the
small size and for the cost isnt worth it, now if they increase the
size then I will reorder.”
Click here for details
May 23 - May 29, 2005
Topical – Procede testimonials
“I have tried procede and it seems that it is nothing more than a
very serious acid peel. The area on my temple areas where I applied it
became very red almost like a very bad sunburn and then precipitated a
peel and a healing. That area on my forehead and temples is still
somewhat red after 4 days. “
Click here for details
May 23
- May 29, 2005
Topical
/ Reference – Anti-inflammatory agents.
A recap of some of the earlier discussion on anti-inflammatory agents.
Click here for details
May 16 - May 22, 2005
Topical – a-keratin-1.2. trial
Lipoxidil.com is accepting applications again for a trial of the new
product a-keratin-1.2. a-keratin-1.2 is designed to break up fibrosis
and is only intended for complete bald spots.The treatment area should
be complete bald for more than one year up to 5 years. Approved
applicants will receive free treatment for 6 months.
Click here for details
May 16 - May 22, 2005
Topical – Alpecin (caffeine based treatment) testimonials
If inflammation is caused by DHT, then Alpecin must be working on DHT
because my inflammation is gone! not reduced , gone!”
Click here for details
May 16 - May 22, 2005
Topical – Minoxidil, quitting the treatment.
“I've only been applying it to my temples and the area between my
receded temples to maintain the hair there. I quit a week ago and I've
experiences NO shed at all......yet.”
Click here for details
May 16 - May 22, 2005
Topical / Reference – Stress, new patent designed to target
stress induced hair loss.
“One of the factors which has been suspected for some time of
causing premature catagen of the hair follicle which, in the scalp
region, may manifest itself in the form of alopecia or effluvium,
giving rise to hair loss, is stress.”
Click here for details
May 09 - May 15, 2005
Topical – Alcohol, more evidence that this is a bad idea.
“Some people say that there's nothing to worry about with using
topicals based on alcohol. Here's an example
of chronic ethanol administration inducing
IL-1 and TNF-a and adversely affecting bone growth. Given that minoxidil is less effective for those with
follicular inflammation, it's possible that
adding ethanol has adverse effects on the immune systems of those with preexisting inflammation.”
Click here for details
May 09 - May 15, 2005
Topical – Procede discussion.
More follow up discussions about Procede, a topical product that is
widely publicized on late night infomercials citing results in as
little as 48 hours with every 90 day application.
Click here for details
May 09
- May 15, 2005
Topical
– Genistil testimonials
“I am on my 3rd bottle of Genistil from lipoxidil.. hairloss in
shower have reduce to less then 10 strands of hair, my vellous hair
along the hairline have all thicken and grew long...”
Click here for details
May 09
- May 15, 2005
Topical
– Fluridil results.
“My regimen is simple but very effective in the fight against hair
loss and somewhat effective in the "regrowth" department.”
Click here for details
May 02 - May 08, 2005
Topical – Alcohol: IL-1 alpha inhibits human hair follicle growth
and hair fiber production.
More discussion about alcohol’s potential harm to hair follicles.
“In the presence of 10 ng/ml IL-1 alpha, the growth of cultured
human hair follicles ceased within 2-4 days, whereas control hair
follicles grew for a period of 7-10 days. IL-1 alpha also inhibited
hair fiber growth, but with an onset which occurred 3 days later than
that of follicle growth inhibition.”
Click here for details
May 02 - May 08, 2005
Topical / Reference – RU 58841-myristate--prodrug development for
topical treatment of acne and androgenetic alopecia.
“Acne and androgenetic alopecia are linked to androgen effects and
therefore should improve following topical application of
antiandrogens. We present a new antiandrogen prodrug, RU
58841-myristate (RUM) for topical therapy.”
Click here for details
May 02 - May 08, 2005
Topical – Alcohol, heated discussion about its merit in hair loss
preparations.
Another informative thread about the merits of alcohol in hair loss
preparations as well as a topic on the types of liposomes to use.
Click here for details
May 02 - May 08, 2005
Topical / Reference – Minoxidil Response & Inflammation
“Only 55% of male pattern AGA patients with microinflammation had
hair regrowth in response to minoxidil treatment, which was less than
the 77% of patients with no signs of inflammation, suggesting that, to
some extent, perifollicular microinflammation may account for some
cases of male pattern AGA which do not respond to minoxidil. Another
study on 412 patients (193 men and 219 women) confirmed the presence
of a significant degree of inflammation and fibrosis in at least 37%
of AGA cases.”
Click here for details
May 02 - May 08, 2005
Topical / Reference – Minoxidil Effectiveness & Limitations
of Human Occipital Scalp Hair Follicle Organ Culture
The current study aimed to clarify whether organ culture of human
scalp anagen VI hair follicles is a suitable in vitro test system for
reproducing, and experimentally dissecting, the recognized in vivo
hair-growth-promoting capacity of minoxidil.
Click here for details
May 02 - May 08, 2005
Topical / Reference – IGF-1 (Insulin-like Growth Factor 1)
Deficiency & Hair Loss
Laron syndrome (primary growth hormone insensitivity): a unique model
to explore the effect of insulin-like growth factor 1 deficiency on
human hair.
Click here for details
May 02 - May 08, 2005
Topical – Curis’ Hedgehog Signaling Treatment
“Hedgehog is one of many cell-signaling pathways that scientists are
scrutinizing. And Curis hopes it will work wonders on thinning pates
of both males and females. When you see a lustrous head of hair,
chances are it's at least partly due to healthy Hedgehog signaling,
which prompts the body's multitalented stem cells to proliferate
around follicles, initiating hair growth. By activating Hedgehog,
Curis' drug targets hair growth at its root, so to speak.”
Click here for details
Apr 25 - May 01, 2005
Topical – Procede Update from forum members.
“I have stated that I have had some re-growth in the temple area
that hasn't had any hair for over ten years. The crown area feels
fuller than it has in years. I will take the three month pics and will
be able to see what my progress looks like.”
Click here for details
Apr 25 - May 01, 2005
Topical – Fluridil Updates from Members.
“Fluridil will not regrow all your lost hair, but it might keep the
rest from falling out. I've been on it for over a year, I would love
to tell you that it grew my hair back, but that is not the case. But
it does seem to halt hair loss.”
Click here for details
Apr 25 - May 01, 2005
Topical – Kerasome, members’ opinions.
“Kerasome, on the other hand, contains real human hair particles and
thus has the same sheen, textural qualities, and color variation as
human hair. It blends in seamlessly with the users own hair. Although
a variety of different colors are available, a perfect match is not
necessary as real hair isn’t all the same color and neither is the
product. Kerasome is also effective in covering graying roots.”
Click here for details
Apr 25 - May 01, 2005
Topical / Reference / Alerts – Alcohol Induces Cell Death?
A most informative discussion as to whether alcohol based hair
products is a bad idea. “Caspases, a family of proteases, are best
known as executioners of apoptotic cell death and their activation are
considered as the "point of no return" commitment to cell
death.”
Click here for details
Apr 25 - May 01, 2005
Topical – Photonic, New Hand Held Laser on the Market for Hair
Loss.
Comparison chart showing the difference between Photonic and other
hand held laser on the market for the treatment of hair loss.
Click here for details
Apr 25 - May 01, 2005
Topical / Reference – Adenosine, charts, illustrations &
comparison to Minoxidil.
Research and hypothesis on intracellular signaling by Adenosine
stimulation on Dermal Papilla cell and Adenosine’s effectiveness as
a treatment for androgenetic alopecia. Include charts and comparison
to Minoxidil.
Click here for details
Apr 25 - May 01, 2005
Topical – Silanol
"A cocktail of specific active agents to combat falling hair.
This is the solution! Stymulactine 21 with Silanols is a non-greasy
product. Silanols are one of the essential factors in the cellular
activity of hair roots, contributing to the resistance of the hair and
scalp.” Include Creatine, Melatonin, zinc pyrrolidone
carboxylic acid etc.
Click here for details
Apr 25
- May 01, 2005
Topical – NanoAdeno, by Fred102
“I created a large batch together with Elsom Research. The Nanosome
Technology from Elsom Research will be used. It will be available via http://www.nanoadeno.com
in the next 2-3 weeks, the page is currently under construction. The
page also will explain the mechanisms of action of the different
ingredients and will give a profound insight in the complex theory of
hair loss.”
Click here for details
Apr 25 - May 01, 2005
Topical – Inflammation Theory to Hair Loss.
“DHT causes inflammation due to mitochondrial cell stress. DHT
inhibits the secretion of IGF-1 in dermal Papilla where also
proinflammatory cytokines are expressed. When IGF-1 is poorly
expressed, the cytokines have no more antiinflammatory antagonist. An
inflammation is always a part of the balding process. It must not be
noticeable. Stress is a big hormonal influence...”
Click here for details
Apr 18 - Apr 24, 2005
Topical – Laser Treatments.
A summary of websites that offer Laser treatment for hair loss.
Click here for details
Apr 11 - Apr 17, 2005
Topical – Minoxidil on a Damp Scalp.
“Yes, it is certainly okay to use on a damp scalp - scalp hydration
has been reported to increase topical drug absorption ten-fold. A good
soak in the tub prior to application is ideal.”
Click here for details
Apr 11
- Apr 17, 2005
Topical
/ All Natural – The Formulator-
formulate your own Topical.
“We developed the technology which is nothing short of a revolution
in the way skincare can be imagined. Customized and personalized
formulations of as little as one retail-size skincare jar with your
pre-selected ingredients are now a reality. The Formulator provides an
assisting tool that will help you formulate your own retail size
skincare product. You can select your ingredients from a substantial
list of choices which will keep growing.”
Click here for details
Apr 11
- Apr 17, 2005
Topical
– Fluridil Side Effects?
“After about 10 minutes I felt all hot and thought I had a fever,
but my temp was normal. Then I started having trouble breathing and
swallowing and my chest tightened up. I got scared and took a wet rag
and scrubbed my scalp with it.”
Click here for details
Apr 11 - Apr 17, 2005
Topical – Minoxidil testimonials.
“I've had excellent results form Rogaine - I only use it on the
temples plus it's only the 2% stuff.”
Click here for details
Apr 11 - Apr 17, 2005
Topical – Nanotechnology to the Rescue.
” JAPANESE SCIENTISTS have created a substance based on
nanotechnology which they claim will help sprout hairs on bald men.
According to the Nihon Keizai Shimbun, the breakthrough is based on
tiny nanoparticles which will penetrate further into a bald pate than
your conventional hair restorer.”
Click here for details
Apr 11 - Apr 17, 2005
Topical / Reference – Flutamide Study using Male Subjects.
“Topical fluridil is nonirritating, nonsensitizing, nonresorbable,
devoid of systemic activity, and anagen promoting after daily use in
most AGA males.”
Click here for details
Apr 04 - Apr 10, 2005
Topical / Reference - Papin
“Papain has anti-inflammatory and keratolytic properties. A
keratolytic agent, such as mild salicylic acid, encourages removal of
dead skin cells from the stratum corneum.”
Click here for details
Apr 04 - Apr 10, 2005
Topical / Reference – Alpecin (Caffeine)
Read 6 clinical studies about Alpecin / Caffeine formulated hair loss
treatment.
Click here for details
Apr 04 - Apr 10, 2005
Topical / Reference – Procede Patents.
Abstracts of Procede patents, “Compositions and method for promoting
the growth of human hair.”
Click here for details
Apr 04 - Apr 10, 2005
Topical / Reference – New Delivery Systems for Hair Care
Article that discussed the mechanisms of liposomes, ceramides as well
as illustrative chart showing % washed off actives.
Click here for details
Apr 04 - Apr 10, 2005
Topical – Genistil testimonials.
“I have been using Genistil for 8 months now ... Nada ... my opinion
over-priced waste of money that adds the benefit of a foul smell and
the "crusty skin" condition.”
Click here for details
Apr 04 - Apr 10, 2005
Topical / Reference – PMLs containing Keratin
and Capilar Peptides.
"PMLs containing keratin and capillary peptides are the basis of
a wide range of modern treatments against premature hair loss. They
are also known for their properties of protection against external
agents and drastic treatments."
Click here for details
Apr 04 - Apr 10, 2005
Topical / Reference – Clobetasol
” I took GEN-Clobetasol scalp formula. It worked for a relative of
mine so I decided to give it a try. You see DHT causes an inflammatory
response which leads to hair loss. GEN-Clobetasol is an
anti-inflammatory. With this stuff and Saw Palmetto you can have the
hair line of a teenager. I experienced massive regrowth with
Clobetasol.”
Click here for details
Mar 28
- Apr 03, 2005
Topical
– RU58841 testimonials.
“it is not a scam, it has worked wonders for myself as well as many
others. Some simply do not respond, the same as some do not respond to
finasteride or dutasteride (myself included).”
Click here for details
Mar 28
- Apr 03, 2005
Topical
– Adenosine
testimonials.
“So adenosine will trigger ALL receptors at the same time in a non
selective way. Thus, some receptors are antianflammatory, while others
are pro-inflammatory.”
Click here for details
Mar 28
- Apr 03, 2005
Topical
/ Reference – Adenosine Technical
Information.
“Adenosine is a multi-purpose signal molecule that regulates a
variety of cellular functions and is released under conditions of
physiological stress. The actions of adenosine are mediated through
four receptors subtypes (A1, A2A, A2B and A3).”
Click here for details
Mar 21 - Mar 27, 2005
Topical – Shiseido’s Adenogen vs Taisho’s RiUP
”A corporate battle to provide hair loss solutions in Japan heated
up on Monday with the nation's top cosmetics maker Shiseido launching
a new tonic to rival the market leader. Shiseido hopes Adenogen hair
tonic for men, using hair growth stimulant adenosine, will knock
Taisho Pharmaceutical and its RiUP product off the top shelf.”
Click here for details
Mar 21 - Mar 27, 2005
Topical – RU58841 Results.
“Almost two years ago I purchased RU along with a bunch of others
due to the initiative of Richlocks. It was tested and proved to be the
real thing. I also, at about the same time, started Duta once/twice a
week. After about 4-5 months of steady twice a day use...I knew there
was a change. Major...well..”
Click here for details
Mar 21 - Mar 27, 2005
Topical – Minoxidil – Retin-A Combo Success Story.
“I used it without interruption from 1992 to 1999.(between ages of
38-45) worked tremendously; saw results within two months. It was a
stand alone product. Nothing else was needed.”
Click here for details
Mar 21
- Mar 27, 2005
Topical
– Adenogen now being tested by one of our forum members.
” I recieved the Adenogen today. I will keep
you up to date. Here are the instructions: apply 2 times daily, 2 to
2.5 mL each, on dry scalp. To get better results, apply consistently
than applying too much at a time.”
Click here for details
Mar 21 - Mar 27, 2005
Topical – Procede Results and How it Works, a Hypothesis.
“I would have to agree with Tyler. I have tried procede and it seems
that it is nothing more than a very serious acid peel. The area on my
temple areas where I applied it became very red almost like a very bad
sunburn and then precipitated a peel and a healing. That area on my
forehead and temples is still somewhat red after 4 days.”
Click here for details
Mar 21 - Mar 27, 2005
Topical – Procede Results.
Testimonials from another user of Procede. Is it worth the $200?
Click here for details
Mar 14
- Mar 20, 2005
Topical
– Mesenchyme extract.
Can this help?
"Mesenchyme extract is made of cells known as mesenchymal stem
cells. These cells have the ability to become almost any kind of cell
in the body to promote renewal of functional tissues. Mesenchyme works
primarily to increase cellular metabolism by providing rejuvenating
molecules that boost the energy levels in all types of cells"
Click here for details
Mar 07 - Mar 13, 2005
Topical – Fluridil results
”I've been on fluridil for almost 11 months daily (no regrowth, but
hairloss reduced significantly) and then I started to notice that I
urinate much too frequently and I had a strange feeling in my lower
abdomen.”
Click here for details
Mar 07
- Mar 13, 2005
Topical
/ All Natural – Laminaria Angustata
Another round of discussion on Laminaria Angustata and Jacob’s
results so far.
Click here for details
Mar 07 - Mar 13, 2005
Topical – Telostatin (new product)
”Telostatin is the first and only product in its class to directly
stimulate the Anagenic Growth phase of the hair cycle with growth
promoting growth factors for hair. The product is also first in its
class to directly suppress the Catagenic Rest and Telogenic Loss
phases of the hair cycle. The combined result is a hair restoration
product that offers faster results with improved efficacy in problem
treatment areas.”
Click here for details
Mar 07
- Mar 13, 2005
Topical
/ Reference – Adenosine &
Minoxidil study.
“These results indicate that the effect of minoxidil is mediated by
adenosine, which triggers intracellular signal transduction via both
adenosine A1 and A2 receptors, and that the expression of sulfonylurea
receptor 2B in dermal papilla cells might play a role in the
production of adenosine.”
Click here for details
Mar 07
- Mar 13, 2005
Topical
/ Reference / Alert – Tacrolimus can cause
cancer?
“Not all topicals are safe. Below is an article about two topical
immunosupressants that are apparently capable of being absorbed
systemically and possibly causing cancer. If you'll recall, one of the
topicals mentioned in the article (tacrolimus) has been shown in
animal models to induce hair growth. At one time, at least a few
members here were using tacrolimus to treat their MPB.”
Click here for details
Mar 07 - Mar 13, 2005
Topical – Procede, finally a user’s testimonials.
We finally have a forum member who ordered Procede, a widely
publicized product for hair loss that claims to give people results in
48 hours and only need to reapply every 90 day.
Click here for details
Feb 28 - Mar 06, 2005
Topical – Stopping Fluridil.
In the week since stopping Fluridil Ive had that itchy head feeling
sometimes which may be a sign of the alopecia restarting.
Click here for details
Feb 28 - Mar 06, 2005
Topical – RU58841 Results, A Mixed Bag.
“I have been using for past year and half from faith eagle with
decent results. I have at least stopped the loss. I have always
received mine within 7 days. Ru seems to be like any other
anti-androgen, mixed results.”
Click here for details
Feb 28 - Mar 06, 2005
Topical – Adenosine, the homemade formula.
Discussion about making our own Adenosine formula.
Click here for details
Feb 28 - Mar 06, 2005
Topical – Minoxidil results.
“I've been using Minox for about 16 years now and it's done a good
job of keeping most of the hair that I've got (still Norwood 2)but it
hasn't grown me any hair in the areas that I was bald before I started
on it and I've tried it with 2%, 2%/Retin A comb, 5%, 5% Retin A
combo, 5%/ Azelaic Acid combo and 5%/ Pregestorone. I see it as an
insurance policy against further loss but not as a regrowth agent for
the temple/front.”
Click here for details
Feb 28
- Mar 06, 2005
Topical
– Neosil Acquires
OsteoScreen’s Hair Technology, OSH 101.
A summary of recent posts and discussions about OsteoScreen’s new
product for hair loss.
Click here for details
Feb 21 - Feb 27, 2005
Topical / Reference - Curis Presents Study Showing Stimulation of
Hair Growth using a small molecule agonist of the Hedgehog signaling
pathway
"We are very pleased with these results and with the progress
that has been made in our hair growth program. We are also evaluating
the requirements for clinical development in hair growth indications
in order to decide on an appropriate strategy for moving this program
forward."
Click here for details
Feb 21 - Feb 27, 2005
Topical / Reference - Hedgehog and Beta-catenin signaling studies
“We present a model of the interactions between beta-catenin and
hedgehog signaling in the epidermis in which SHH promotes
proliferation of progenitors of the hair lineages whereas IHH
stimulates proliferation of sebocyte precursors.”
Click here for details
Feb 21 - Feb 27, 2005
Topical – Procede discussions. The latest in cosmetic hair
thickener?
”ProCede does not contain Minoxidil. ProCede is a revolutionary new
cosmetic product and the result of years of development and testing.
The worldwide, patent-pending formula contains a unique combination of
drug-free ingredients designed to revitalize hair and help make it
appear thicker and fuller with continued use.”
Click here for details
Feb 21 - Feb 27, 2005
Topical – Minoxidil – good old minoxidil / Rogaine stories
“It made my hair somewhat denser. The improvement was about 15-20%
denser, which helped prevent see-through to the scalp in areas where
my hair was thinning but not yet gone.”
Click here for details
Feb 21 - Feb 27, 2005
Topical – Procede patent found online?
Could this be the patent for the Procede formula? An interesting
discussion about a possible patent for Procede. A new product for hair
loss that has been widely publicized on TV infomercials lately.
Click here for details
Feb 14
- Feb 20, 2005
Topical
- Neosil Acquires Topical Products From OsteoScreen
”Neosil, Inc., a privately held specialty
dermatology company, announced today that it completed in-licensing of
several hair growth products from OsteoScreen, Inc”
Click here for details
Feb 14 - Feb 20, 2005
Topical - RU 58841-myristate--prodrug development for topical
treatment of acne and androgenetic alopecia
”This new study looks at RU 58841-myristate. It's inactive to start
with, but human cells convert it to the active form - the same RU
58841 we all know. They also discuss a new delivery method -- lipid
nanoparticles instead of using alcohol and/or PG solutions as
vehicles. Unfortunately, this study does not address how well this
treatment would actually work in treating MPB or acne.”
Click here for details
Feb 14
- Feb 20, 2005
Topical
– Fluridil results
“I still do, 5 days a week, cheaper, and so far fine. No irritation,
no libido loss, no weight gain, no shed, hair much thicker so i can
let them grow longer.”
Click here for details
Feb 14 - Feb 20, 2005
Topical – Topical Finasteride success stories
“I also use topical fin. all you do is crush 2 or 3 proscar tabs
into your minox and shake. apply to your scalp as you would rogaine.
my frontal hairline responded to nothing until I started doing this.
now I have almost all my hair back.”
Click here for details
Feb 07 - Feb 13, 2005
Topical
– Topical finasteride as a hair loss treatment
” I also use topical fin. all you do is crush 2 or 3 proscar tabs
into your minox and shake. apply to your scalp as you would rogaine.
my frontal hairline responded to nothing until I started doing this.
now I have almost all my hair back..”
Click here for details
Feb 07 - Feb 13, 2005
Topical
– Finasteride in topical preparation may be a viable solution for
hair loss.
” I also use topical fin. all you do is crush 2 or 3 proscar tabs
into your minox and shake. apply to your scalp as you would rogaine.
my frontal hairline responded to nothing until I started doing this.
now I have almost all my hair back..”
Click here for details
Feb 07
- Feb 13, 2005
Topical
/ Reference - Retinoic Acid (Retin-A),
a blessing or a curse ?
Recent debate about the merits of Retin-A in treating hair loss. “The
article says that ATRA makes the keratinocytes more sensitive to UV
radiation, that does not mean that it will kill them by itself (do not
go out in the sun when using retin-a it makes your skin more
suseptible to sun burn probably for the same reason as it causes cells
to more easily commit cell death). Also, an upregulation of TGF-beta2
might be necessary for follicular growth as recently demonstrated by
Dr. Fuchs in her article "A signaling pathway involving TGF-beta2
and snail in hair follicle morphogenesis."”
Click here for details
Feb 07
- Feb 13, 2005
Topical
/ Reference - Role of melatonin
receptors in hair biology
“In conclusion, normal murine hair follicles are indeed
a prominent, direct target for melatonin bioregulation, through MT1,
MT2
and RORalpha melatonin receptors and that at least some of these
regulators are functionally active in situ. The observed hair cycle
dependence of melatonin receptor expression suggests a role of
melatonin
in hair cycle control.”
Click here for details
Feb 07
- Feb 13, 2005
Topical
– Remox III results
“It's almost unbelievable what has happened.. Looking in the mirror
every day and seeing my hair get thicker, it's an amazing thing to
experience when you've gone 3 years trying stuff with no regrowth. The
main regrowth is in the top-frontal area and top-middle area.”
Click here for details
Jan 31 - Feb 06, 2005
Topical / References – TGF & T-Flavone Discussion
”The theory is that androgens bind to receptors - go into the middle
of the cell, trigger production of tgf beta which induces a cascade of
caspases that cause cell death. Theory is t-flav inactivates tgf beta.
How can t-flav (simple ring molecule) deactivate TGF Beta? “
Click here for details
Jan 31 - Feb 06, 2005
Topical / References – Adenosine: new hair loss product by
Shiseido
Adenosine triphosphate (ATP) is considered by biologists to be the
energy currency of life. Leading Japanese cosmetic manufacturer
Shiseido announced that it has discovered a hair-growth property
called adenosine, one of the in vivo substances that exist in the
human body. According to Shiseido, studies have shown that
adenosine directly affects hair papillae, a key in hair production;
consequently, the output of FGF-7, a hair-growth factor, is increased.
Click here for details
Jan 31 - Feb 06, 2005
Topical – PS1 debate
Another round of heated debate on PS1, the hair loss treatment that
eluded most forum members.
Click here for details
Jan 24 - Jan 30, 2005
Topical
– Topical DHT inhibitor might be a better solution for hair loss
than internal medications.
” The blood levels of DHT may play a minor role in Androgenetic
Alopecia but it is the locally produced DHT which plays the major
role. If you look at any physiology text book (such as Guyton's
Medical Physiology) you can see that the majority of DHT production
takes place at the site where it exerts its effects,”
Click here for details
Jan 24
- Jan 30, 2005
Topical
- Lee's
Pharm TB4 Postponed to mid 2006
We are at the stage in preparing the protocol of clinical trial for
this product. This product is in a gel form for topical use containing
"Peptide Thymosin Beta 4" for hair promotion. In viewing of
the current development status, the Group is expected to file the
registration in our region at the end of this year, and we are afraid
that we have to postpond launching this product until Mid 2006.
Click here for details
Jan 24 - Jan 30, 2005
Topical – Pollen Extract based Hair Growth Agent
Füll & Recapeen: Two new products formulated using pollen extract
for hair loss.
Click here for details
Jan 24 - Jan 30, 2005
Topical / References – Biodisposition of Liposome-Encapsulated
Active Ingredients Applied on the Skin
The author concluded that liposomes are suitable vehicles for
selective drug delivery. Depending on the type of liposomes and the
physicochemical properties of the active ingredient and of the
auxiliary agents present in the formula, liposomes can be used mainly
for dermal and also in some cases for transdermal drug delivery.
Click here for details
Jan 24 - Jan 30, 2005
Topical – Liposome Minoxidil Study
” The results clearly demonstrated that the liposomal encapsulation
was responsible for the increased minoxidil concentration within the
skin layers. In some cases, both the dermal and transdermal delivery
was increased as a result of liposome encapsulation.”
Click here for details
Jan 17- Jan 23, 2005
Topical – RU results
Discussion of RU results among forum members
Click here for details
Jan 17- Jan 23, 2005
Topical - Permeation of cyproterone acetate through pig skin from
different vehicles with phospholipids
A study which suggests that effectiveness of liposomal formulations
and its permeation was strongly dependent on the lipid content. The
higher the lipid content, the higher was the CPA permeation. Extruding
procedures for decreasing the particle size of the liposomes resulted
in a two-fold increase in CPA permeation compared to the unextruded
liposomes
Click here for details
Jan 10
- Jan 16, 2005
Topical – Minox-Finasteride formula, positive feedback
”For over 3 years now and the results are that it stopped my hair
loss.”
Click here for details
Jan 10 -
Jan 16, 2005
Topical: SLS, Hairloss and Health Concerns.
This is another chapter of the never-ending debate as to whether SLS
in shampoos is causing hairloss and other health problems. Several of
our forum members have posted very informative and well documented
studies to further the debate on this topic. So is it safe to use
shampoos that contain SLS ?
Click
here for details
Jan 10 - Jan 16, 2005
Topical
– Healthier Hair Without Excessive Shampooing
“I have gone from shampooing my hair twice per day to completely
stopping. I have been following this for around 4 weeks now and my
hair is definitely better.”
Click here for details
Jan 10
- Jan 16, 2005
Topical
– Update
from Elsom Research- Laminaria in EquiClear now
"We have come up with two new formulations for EquiClear:
EquiClear + Glutathione and EquiClear + Laminaria (with Laminaria
Digitata). The Laminaria formulation also includes extracts of
cinnamon and turmeric (curcumin), which is not staining though it is
quite colorful. The glutathione formulation also includes superoxide
dismutase (SOD) and cysteine to protect the glutathione,”
Click here for details
Jan 10 - Jan 16, 2005
Topical – Topical Spironolactone & Minoxidil Success Story
“I really think that it is making a difference. The remaining bald
portion of my temples actually have black hairs popping up. The bald
spot is slowly shrinking.”
Click here for details
Jan 10 - Jan 16, 2005
Topical – Fluridil Results
Dr. Dut reported good results on Fluridil
Click here for details
Jan 10 - Jan 16, 2005
Topical – Fluridil Results
Forum members solicited opinions on Fluridil’s effectiveness.
Click here for details
Jan 03 - Jan 09, 2005
Topical – InFlamil + Genistil-R Success Story
“Using it for 4 months now - hairloss almost zero. Scalp very
healthy. Slight regrowth in the thinning areas - none in the complete
balding areas.”
Click here for details
Jan 03 - Jan 09, 2005
Topical
– "The Perricone Promise""
The Perricone Promise introduces the powerful new tools in the
anti-aging arsenal, peptides and neuropeptides. These protein-like
substances can revitalize skin and hair, improve mental clarity and
energy, promote heart health, help decrease the risk of certain forms
of cancer, and strengthen the immune system"
Click here for details
Jan 03 - Jan 09, 2005
Topical
– Is Shampoo Hair Poison ?
A heated discussion about the merits of shampoo and whether it
actually causes hair loss in men and women.
Click here for details
Jan 03 - Jan 09, 2005
Topical – OXICELL
"OXICELL represents a significant breakthrough in the field
of natural medicine, particularly in the area of antioxidant
supplementation. OXICELL is a metabolic cream that transports a
stabilizedform of glutathione (GSH) and superoxide dismutase (SOD)
into the bloodstream via transdermal liposomal delivery methods. The
plasma markers of GSH and SOD are not raised when these are supplied
orally; therefore, effective transport into the bloodstream via
liposomaldelivery as found in OXICELL is preferential.1The transdermal
method of delivery, known as liposomal delivery, is one in which lipid
spheres called liposomes surround GSH and SOD, transporting it through
the skin until it reaches the blood supply"
Click here for details
Dec 27 - Jan 05, 2005
Topical - Tacrolimus
Ineffective for Alopecia Areata Patients
Eleven patients with alopecia areata affecting 10% to 75% of the
scalp, average duration 6 years, had no terminal hair growth in
response to tacrolimus ointment 0.1% applied twice daily for 24 weeks.
Treatment failure may reflect insufficient depth of penetration of the
ointment formulation and less than optimal patient selection.
Click here for details
Dec 27 - Jan 05, 2005
Topical – Hydrocortisone (Scalpicin), more Success Stories
It's nice to see that there is someone else who recognizes the
benefits of topical hydrocortisone! It's always amazed me that more
hair loss guys haven't realized what a powerful medicine
hydrocortisone to fight inflammation. I rub Scalpicin into my scalp
every Sunday night. I use it in the form of extra-strength scalpicin,
which is 1 percent hydrocortisone and is available at any drug store
OTC.
Click here for details
Dec 20 - Dec 26, 2004
Topical - Liquid Topical Hydrocortisone Success Story
”Liquid topical hydrocortisone works FOR ME to reduce my hair loss
dramatically. Some people are very cautious about using it because of
possible side effects, which I would agree... I use it once or twice a
week and it works.”
Click here for details
Dec 20 - Dec
26, 2004
Topical /
Drugs / Natural - Fin/Minox/Nizoral/Beta Sitosterol success story
"The
top and top back of my head has thickened up some, Id say about 125%
of what it was. New growth (vellous hairs finally became terminal and
are about 1/2") on my left temple, especially the front left
corner, even more small dark hairs are on the outer edges of my bald
temple, which look promising.."
Click here for details
Dec 20 -
Dec 26, 2004
Topical: Shiseido To Introduce New Product Containing
ADENOSINE. Leading Japanese cosmetic manufacturer Shiseido
announced that it has discovered a hair-growth property called
adenosine, one of the in vivo substances that exist in the human
body. According to Shiseido, studies have shown that adenosine
directly affects hair papillae, a key in hair production;
consequently, the output of FGF-7, a hair-growth factor, is
increased. The product has received approval as an active
ingredient for medicated cosmetics from the Ministry of Health, Labor
and Welfare. Launch date: March 2005.
Click here for details
Dec 20 -
Dec 26, 2004
Topical: Adenosine Responsible for Minoxidil’s
Effectiveness as a Hairloss Treatment.
Recent studies indicate that the “effect of minoxidil is mediated by
adenosine, which triggers intracellular signal transduction via both
adenosine A1 and A2 receptors, and that the expression of sulfonylurea
receptor 2B in dermal papilla cells might play a role in the
production of adenosine.”
Click here for details
Dec 20 -
Dec 26, 2004
Topical: Should Coal Tar Products Carry Cancer
Warnings?
Many of us use shampoos formulated with coal tar to treat dandruff and
certain scalp inflammatory conditions. There are discussions whether
topical treatments containing coal tar are dangerous. There are in
fact studies which show that coal tar can cause cancer if applied
topically. For example, a study conducted by University Medical Center
Nijmegen, The Netherlands suggested that “because of the potential
carcinogenicity of coal tar, as clearly demonstrated both in animal
studies and from occupational exposure, careful consideration should
be given to the use of coal tar preparations in dermatological
practice.”
Click here for details
Dec 06 - Dec 12, 2004
Topical – Melatonin study.
This pilot study is the first to show that topically applied melatonin
might influence hair growth in humans in vivo. The study involved 40
women suffering from diffuse thinning or androgenetic alopecia.
Click here for details
Nov 22 - Nov
28, 2004
Topical - Topical
Melatonin Study – vehicle used
"The participants applied a 0.1% melatonin-alcohol solution
(melatonin, high-purified; Helsinn Chemicals, Biasca, Switzerland) or
alcohol solution alone topically once daily in the evening for 6
months. The daily amount to be applied was 1 mL given in eight spray
hits (8 X 0.128 mL = 1.024 mL)."
Click here for details
Nov 22 - Nov 28, 2004
Topical – Lasercomb
Before & After Photos.
Lasercomb is featured in NBC Dateline. Read testimonials as well
as before and after photos.
Click here for details
Oct 25 - Oct 31, 2004
Topicals: Is liposomes/nanosomes a superior and cost effective
vehicle for delivering minoxidil ?
A study by AmorePacific R&D Center, Yongin-si, Korea showed that
“there was no significant difference in the activity of anagen
induction of C57BL/6 mouse between 3 % minoxidil solution (propylene
glycol and ethanol) and 0.5 % minoxidil nanoparticle solution.”.
Bryan raised an interesting issue as to whether liposomes/nanosomes
are uniquely able to do anything that ordinary vehicles can't do, when
simply used in larger amounts and/or concentrations. Click here for a
lengthy discussion.
Click here for details
Oct 25 - Oct 31, 2004
Topicals: Ethanol and Caspase-3: revisiting the alcohol
issue in topical
minoxidil products.
Some studies have suggested that ethyl alcohol upregulates caspace-3
and can have a negative effect on hair. The following is a very
informative discussion with numerous useful links and references about
this topic, courtesy of Fred102. Click here to read forum discussion.
Click here for details
Oct 25 - Oct 31, 2004
Topicals: Evidence showing that SOD can penetrate the skin.
SOD (Superoxide Dismutase) are enzymes which destroy superoxide free
radicals and prevent the cellular damage that free radicals cause.
Some studies have shown that SODases can stimulate hair growth and
decrease hair loss. Here is a study which confirms that SOD can
penetrate the skin. Click here to read the abstract.
Click here for details
Oct 25 - Oct 31, 2004
Topicals: Clinical evaluatioin of DH-3923 topical solution in the
treatment of male pattern baldness:
a multi-center open trial. Study conducted by J. Nakayama1, K. Toda2,
S. Harada3 Dep. of Dermatology, Fukuoka University School of Medicine,
Fukuoka1, TODA Dermatology Clinic Councilor, Tokyo2, Kanto Medical
Center NTT EC, Tokyo, Japan3.
A multicenter open trial was conducted in 86 subjects with male
pattern baldness to evaluate the efficacy and safety of DH. Each
subject took 2mL of DH twice daily for 24 weeks in this study. The
results confirmed the efficacy and safety of DH for male pattern
baldness. Click here to read the abstract:
Click here for details
Oct 25 - Oct 31, 2004
Topicals: Connection between Vitamin D3, PTHrP and hair growth.
A lengthy discussion. Some studies have shown that Vitamin D3
downregulates PTHrP and may act as a promising BMP4 inhibitor. Click
here to read forum discussion.
Click here for details
Oct 25 - Oct 31, 2004
Topicals: Ellagic Acid, an anti-oxidative suppressor of TGF-B
and prolongs anagen phase of murine hair follicles. Information
provided by courtesy of Fred102 in the topical forum. Click here for
forum discussion and abstracts of clinical studies.
Click here for details
Oct 25 - Oct 31, 2004
Topicals: Triamcinolone Stimulates bFGF Production and Inhibits
TGF-1 Production by Human Dermal Fibroblasts. Information courtesy of
Fred102 in the Topical Forum. "Basic FGF is mitogenic and
chemotactic for both fibroblasts and endothelial cells and is one of
the most potent stimulators of angiogenesis." Click here for
forum discussion.
Click here for details
Oct 25 - Oct 31, 2004
Topicals: AS101 powerpoint presentation now available online,
courtesy of Jonsy.
“The effects of AS101 in vivo and in vitro as an immunoenhancing
and antiviral agent has been reported and documented in the past few
years of intensive research conducted in Israel and abroad on murine
models and human subjects. In contrast to other drugs now being
researched, AS 101 has no toxicity and
practically no side-effects. AS101 was also found to prevent Alopecia
(hair loss) in cancer patients receiving chemotherapy treatment.”
Click
here for forum discussion.
Click
here for the entire AS101 presentation.
Oct 25 - Oct 31, 2004
Topicals: Super Strength Minoxidil 12.5%.
Dr. Oscar Klein now offers 12.5% Super Strength Minoxidil with 0.025 %
Tretinoin, and 0.1 % Hydrocortisone. To find out if you are a good
candidate for the Super Strength minoxidil formula, please contact Dr.
Oscar Klein for a free
no obligation consultation. During the consultation, Dr. Klein will
work with you to decide the best course of action. Not every case is
the same. Dr. Klein will make decisions that consider your age,
gender, and hair loss history, and other factors. No purchase is
required, so you can feel free to call anytime to see what is best for
you. If you would prefer to contact Dr. Klein on-line, you may do that
as well. In any case, you will have the opportunity to speak with an
expert physician for a free, no obligation consultation before you
decide to get
started.
Physician's Hair Growth
Oscar Klein, M.D. - Medical Director
62 Crosby Street
New York, NY 10012
drklein@physicianshairgrowth.com
Call toll free: 1-800-99HAIR4
Click here to access Dr. Klein’s website: http://www.physicianshairgrowth.com
Oct 25 -
Oct 31, 2004
Topicals & Drugs: 5% Topical Spironolactone found to be an
effective DHT inhibitor. Recent study shows that 5% topical
spironolactone cream acts as an antiandrogen in human sebaceous
glands, competing with DHT receptors and producing a decrease of
labelled DHT. No side effects were noted in this long term study.
Berardesca E, Gabba P, Ucci G, Borroni G, Rabbiosi G. Department of
Dermatology, University of Pavia, Italy.
Click here for details
Oct 25 - Oct 31, 2004
Topical: Lion Corp analyzes 1185 genes in Dermal Papilla Cells.
Innovate is the end product of Lion Corp's study on the expression of
1185 genes. Recent contact with a researcher at Lion Corp. did not
reveal when or where they will publish the results of their clinical
trials with Innovate, but they have made a study on the expression of
1185 genes. It will be in JDS soon (still In Press, not yet on PubMed
or Ingenta). The signal ratio for BMP2 in dermal papilla cells from
balding areas of AGA patients were 0,04 compared to non-balding
non-AGA DPCs. For ephrin A3 the signal ratio was 0,01. Information
courtesy of MartinB in the Topical Forum.
Click here for details
Oct 25 - Oct 31, 2004
Topical: Emu Oil: nature's best anti-inflammatory agent. Emu
oil is a chemical derived from a kind of bird commonly found in
Australia.
Touted as one of nature's best inflammatory agents, research has shown
that emu oil can have positive effects on various kinds of skin, hair
and scalp disorders. Check out the most comprehensive summary for emu
oil and its potentials as a treatment for hairloss.
Click here for details
Oct 25 -
Oct 31, 2004
Topicals / Drugs / Hair Transplant / Hair Multiplication: 4th
Intercontinental Meeting of Hair Research Societies. All those science
buffs should read this. Numerous articles from hair
multiplication research to minoxidil studies. Don't miss this.
Click here for details
Jul 05 -
Jul 11, 2004
Topical: Fluridil overview - drug research development. An all
new topical anti androgen for hair loss.
Click here for details
Jun 28 -
Jul 04, 2004
Topical: "Collagen metabolism is a novel target of the
neuropeptide alpha-melanocyte-stimulating hormone" - a
possible mechanism that works against grey hair and fibrosis and
protects keratinocytes from oxidative stress and UV induced apoptosis.
Click here for details
Jun 07 - Jun 13, 2004
Topical: Peer reviewed study - Minoxidil sulfate is the active
metabolite that stimulates hair follicles. Dr. Lee talks about Minoxidil Sulfate
as a potent hair loss treatment.
Click here for details
Jun 07 - Jun 13, 2004
Topical: NF-kappaB specifically activates BMP-2
gene expression.
Click here for details
Jun 07 -
Jun 13, 2004
Topical: Medicaments comprising relaxin and their use. Relaxin
patent abstract. Invention directed to a method of using relaxing to
treat androgenetic alopecia.
Click here for details
May 24 -
May 30, 2004
Topical: HairMedics to offer free consultation for those
interested in minoxidil and finasteride products.
Click here for details
Apr 19 -
Apr 25, 2004
Topical: Targeting the mitochondrial (powerhouse of cells) when
treating hair loss.
Click here for details
Apr 12 -
Apr 18, 2004
Topical: Cpyroterone acetate in topical liposomal vehicles found
to be equally effective as oral antiandrogen medication.
Click here for details
Apr 12 -
Apr 18, 2004
Topical: Innovate before and after photos.
Click here for details
Apr 05 -
Apr 11, 2004
Topical: Topical spironolactone found to be an effective
antidrogen on human's sebaceous glands.
Click here for details
Mar 22 -
Mar 28, 2004
Topical: Effect of minoxidil on proliferation and apoptosis in
dermal papilla cells of human hair follicle.
Click here for details
Mar 15 -
Mar 21, 2004
Topical: New study shows how minoxidil stimulates hair growth.
Click here for details
Mar 15 -
Mar 21, 2004
Topical & All Natural: New study found topical melatonin
effective in increasing anagen hairs in female pattern baldness
patients.
Click here for details
Mar 15 -
Mar 21, 2004
Topical: New RU58841 summary page where you can find storage and
preservation instructions as well as other relevant information.
Click here for details
Dec 15 - Dec 21, 2003
Topicals: Hair follicle growth factor proteins - new patent
application by Dr. Kim and Dr. Jang in Korea: "The present
invention relates to novel hair follicle growth factor (HFGF)
proteins, genes encoding HFGFs, methods for preparing HFGF proteins
and therapeutic uses of HFGF proteins".
Dec 08 - Dec 14, 2003
Topicals: OsteoScreen December 2003 patent application -
Inhibitors of proteasomal activity for stimulating bone and hair
growth. This invention relates to "compounds that inhibit the
activity of the proteasome or the production of proteasomal proteins
and promote hair growth and the production of hair follicles and are
thus useful in stimulating hair growth, including hair
density."
Nov 17 - Nov 23, 2003
Topicals: WSMR HairSwitch
Peptide, click here to view the latest before and after photos.
Nov 10 - Nov 16, 2003
Topicals: Curis Issued U.S. Patent on Method for
Promoting Hair Growth through the use of agonists (activators) of the
Hedgehog signaling pathway, the patent entitled "Regulation of
Epithelial Tissue by Hedgehog-like Polypeptides and Formulations and
Uses Related Thereto."
Oct 06 - Oct 12, 2003
Topicals: FDA Approved Phase I/II Human Clinical Trials Begin for PTH
7-34 Encapsulated in a Novasome Cream to Treat Chemotherapy-Induced
Alopecia.
(email hairsite@aol.com
if this article is no longer available online).
Sep 15 - Sep 21, 2003
Topicals: Interview with BioPhysica on Eucapil® (fluridil) - "A
Novel Topical Antiandrogen" According to Dermatologic Surgery.
Sep 01 - Sep 07, 2003
Topicals: Check out Remox user Algorithm's before and after
pictures.
Aug 25 - Aug 31, 2003
Topicals: Lion's "Mouhatsuryoku Innovate" hair nourishment
product available in Oct, 2003. New hair product that uses Cytopurine
(6-benzyl aminopurine) to increase the presence of hair growth
promoting signals, and interrupts hair depilation signals.
Jun 16 - Jun 22, 2003
Topical: OsteoScreen's lead compound OSH101 now in Phase I clinical
trials (human toxicology studies with an endpoint in Q3-2003).
OsteoScreen plans to take OSH101 into Phase II trials (dose ranging)
later in 2003. Information courtesy of Jacob in Topical forum.
Apr 14 - Apr 20,
2003
Doctors & Experts:
Doctors & Experts forum now taking questions from the public. Dr.
Bazan, Dr. Campbell, Dr. Cole, Dr. Gho, Dr. Jones, Dr. Woods and many
others will be taking your questions and doing online consultation for
hair transplantation.
Mar 31 - Apr 06, 2003
Topical: BX3.4's pulsed electromagnetic hair
management system now available in the United States. Find out why
this new treatment has recently made major news in Europe.
Feb 24 - Mar 02, 2003
Topical: March 1, 2003: HairSwitch peptide's first
official trialists results brought to us by Trey.
Feb 10 - Feb 16, 2003
Topical: Fluridil information as well as before and
after pictures. Information courtesy of Indy84 and Dave.
Jan 20 - Jan 26, 2003
Topicals: HairSite contacted by three WSMR's
HairSwitch peptide trialists with brief interim results to
report.
Jan 20 - Jan 26, 2003
Topicals: Trey, one of the most trusted names in our
forums, speak up about WSMR's HairSwitch peptide in light of the
flurries of negative press about the company.
Dec 30 - Jan 05, 2003
Topicals: Dr. Kenneth Skinner speaks about WSMR'S
peptide treatment for hair loss.
Dec 30 - Jan 05, 2003
Dr. Kenneth Skinner speaks about WSMR'S peptide treatment for hair
loss.
Patent issued to Dr. Fossel's transdermal hair regrowth system
involving L-Arginine.
Click here.
Prospective test patient request form for WSMR's peptide trials. All
submitted information are forwarded to WSMR for screening
purposes.
Click here.
Peptide frenzy. WSMR's press release and related stories about FLEX
S1, 2 peptide, including evidence of patient results and JTR's
personal opinion about WSMR.
Click here.
S.I. Foote's theory revisited. The Hydraulic Influence in Androgen
Related Hair Growth. Implications in Autoimmune Disease.
Click here.
Dr. Lindenbaum's Follicle Nutrient Serum (FNS) has been available
for a month now. HairSite has compiled all FNS testimonials, good and
bad, in the Personal Journal forum.
Click here.
Bacteria Induced Baldness - 10 HairSite regulars participated in
Growth Response free trial.
Click here.
Bryan offered an excellent hair count analysis between Minoxidil and
Dutasteride in Dutasteride forum 23. Read Bryan's analysis as well as
opposing views.
Click here.
Dr. Holick, Boston University, has agreed to answer PTHrP and Emu Oil
questions in Doctors & Experts Forum.
Click here.
Skin Medica introducing topical skin rejuvenation system TNS
formulated with VEGF: the cell growth factor that has been clinically
proven to maintain follicles in the anagen phase. Posters in Topical
forum (#16) are considering less expensive alternatives to obtain VEGE.
Click here.
Dr. Razack releasing 3rd version of Crinagen with added potency
of Proanthocyanidin.
Click here.
Proanthocyanidins from grape seeds promote proliferation of mouse hair
follicle cells in vitro and convert hair cycle in vivo.
Click here.
Procyanidin Oligomers - all natural minoxidil.
Click here.
Dr.
Razack talks about Tea Tree Oil Shampoo as an anti-inflammatory agent
for hair loss.
Click here.
Nov 04 -
Nov 10, 2002
Patent Issued for Revolutionary Hair Growth System, According
to Strategic Science & Technologies, Inc.
Nov 04 -
Nov 10, 2002
Current Technology Retains Regulatory Consultant To Assist In
ETG Hair Loss Treatment Application To The FDA.
Oct 28 -
Nov 03, 2002
Announcement: WSMR is currently redesigning the entire HairSwitch
website. The site is temporary unavailable. Also, there will be press
release available to the mass media very shortly. The upcoming press
release will supersede the October 1, 2002 version.
Oct 21 -
Oct 27, 2002
Peptide frenzy continues. Prospective test patient's request
form now available online.
Oct 14 -
Oct 20, 2002
JTR, one of the most valuable contributors in HairSite, gives
WSMR's FLEX S peptide seal of approval.
Oct 14 -
Oct 20, 2002
Current Technology Launches New PR Campaign with
Presentation by Professor Arthur Pilla at San Francisco Biotech /
Medtech Conference.
Oct 14 -
Oct 20, 2002
Peptide frenzy @ HairSite - recent press release by WSMR
about a certain peptide has caused a huge commotion in HairSite. We
feel very privileged that WSMR is willing to disclose patient results
to HairSite visitors on a restricted basis.
Sep 30 -
Oct 06, 2002
Dr. Fuchs' article which suggests that follicles can be
created and existing ones can be rejuvenated. Information courtesy of
WB. Contact HairSite for archived copy if link no longer active.
Sep 30 -
Oct 06, 2002
A scientific perspective of why your follicles die.
Information courtesy of NorCal Scott in Dutasteride forum.
