Hair Loss Forum - TOCO-8 - Claims 41% increase in hair count in 5 months
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col

14.02.2008, 04:21
(edited by col, 14.02.2008, 04:41)
 

TOCO-8 - Claims 41% increase in hair count in 5 months (Hair Loss Supplements)

Just posted by "jasonlv" on another BB.

Its a Vitamin E complex containing ALL 8 forms of Vitamin E in a powder form to add to water etc.

It has received a US Patent for hair growth in 2007.

US Patent # 7,211,274
Hair growth formulation
US Patent Issued on May 1, 2007

In this Patent they claim their study showed an "increase in the number of hairs is 42.4 (±40.9%) over 5 months."

Its only $29 for a 60 day supply.

TOCO-8 website:
http://www.primordialperformance.com/toco.cfm




col is located in [NA] and he is available to meet: NO


Post reply
col

14.02.2008, 04:22

@ col

TOCO-8 - Study claims 42% hair growth in 5 months

Here is the actual study they quote above:


United States Patent 7211274
http://www.patentstorm.us/patents/7211274-fulltext.html

DETAILED DESCRIPTION OF THE INVENTION

Effect Of Tocotrienol Supplementation On Hair Growth

Study Design

A randomized, double blind, placebo-controlled two groups parallel study was conducted to compare the effect of a mixture of tocotrienols, comprising α-, γ-, and δ-tocotrienols and alpha-tocopherol, with placebo on hair growth. All volunteers were randomized to receive one capsule comprising either (i) a mixture of tocotrienols and alpha-tocopheral, or (ii) a placebo, twice daily after food over a period of at least 5 months. They were seen for an efficacy evaluation every month throughout the study. The control was a placebo capsule containing 600 mg of soya bean oil, and the tocotrienol formulation consisted of capsules containing a mixture of about 50 mg of tocotrienols and about 23 i.u. alpha-tocopherol. The entire study took 15 months for completion.

Although the preferred embodiment of the formulation is in the form of soft gelatin capsule, other oral pharmaceutical dosage forms are not excluded. The preferred dosage range of tocotrienols for oral consumption is from about 20 mg to about 1500 mg/day. The formulation may also be applied topically and may be in the form of a cream, a lotion, an ointment, a gel, a liquid, or any other topical form. The concentration of tocotrienols used in the topical formulation is about 1.0%, and the minimum concentration of tocotrienols in any formulation is about 0.1%.

Inclusion Criteria

Volunteers of 15 years of age or older and in good general health were recruited into the study. Alopecia must have present for least 2 months and the areas alopecia must not have any visual evidence of new hair growth. Volunteers previously exposed to minoxidil were ineligible to participate in the study, as were patients who have used hair-restorers or systemic drugs like steroids, antihypertensives, cytotoxic compounds, vasodilators, anticonvulsant drugs, β-blockers, spironolactone, cimetidine, ketoconazole, estrogens or progesterons within the previous three months. Patients experiencing hair loss due to thyroid disease, adverse drug reactions, scalp or hair trauma, structural hair shaft abnormalities and lichen planus were excluded from the study.

Efficacy Evaluation

Two parameters were chosen to evaluate the efficacy of tocotrienols and alpha-tocopherol supplementation: i) Hair count--hair count served as the primary efficacy measure. An area of 2×2 cm was selected in the area of hair thinning for each patient, and the two opposing corners of the square were permanently marked (using a 4 cm2 wire template) to ensure that the hair in the same area was counted at each visit. ii) Weight of hair--a small tuft of hair (at least 20 strands) within the demarcated area was clipped horizontally. Twenty strands were randomly chosen and cut into 1 cm in length. The total weight was obtained using a microbalance and the mean weight was recorded.

All of the two parameters were obtained at baseline and every month thereafter during the study. Only the terminal hair growth was recorded and analyzed.

Results of Hair Growth Studies

Nineteen patients (14 men and 5 women) entered the study and completed at least the first 5 months of therapy. Their ages ranged from 23 to 59 years. The mean duration of current alopecia episode was approximately 5 years. The extent of alopecia was as follows: less than 25%, 6 patients; 25 49%, 8 patients; 50 74%, 4 patients; 75 99%, 1 patient.

Eleven volunteers were randomized to receive the tocotrienol formulation supplementation while 8 volunteers were in the placebo group. Comparability of the treatment groups with respect to initial hair counts as well as the weight of hair was assessed. No statistically significant difference between treatment groups was detected for any of the above characteristics.

At the end of the supplementation period, all volunteers in the tocotrienol formulation group had positive results, recording an increase in the number of hairs in the evaluation area. Seven volunteers (64%) showed regrowth of between 10 35% while 3 volunteers (27%) had 50% or greater regrowth. One volunteer had regrowth of more than 100%. The mean percentage of increase in the number of hairs is 42.4±40.9% (mean±SD). (Table 1 and FIG. 1). The increase is statistically significant (p<0.05) when analyzed using paired sample t-test. On the other hand, of the total eight volunteers in the placebo group, two showed hair regrowth, two had hair loss while the other four did not show any significant changes in the number of hairs. The mean percentage of increase was 1.4±13.8%. No statistically significant difference (p>0.05) in the number of hairs was detected between baseline and post-supplementation, thus indicating that the placebo effect did not occur during this study.

However, in terms of the weight of the hair, no statistically significant difference (p>0.05) between pre- and post-supplementation was detected for both groups of volunteers (tocotrienol and placebo). The mean percentage of weight increment was 16.4±42.5% in the tocotrienol formulation group while that of the placebo group had an increase of 5.7±40.1%. (Table 2).

The above-mentioned studies therefore indicate that supplementation with a formulation comprising a mixture of tocotrienol, alpha-tocopherol and pharmaceutically acceptable excipient appears to promote hair growth and increase the number of hair in persons experiencing hair loss. The choice of pharmaceutically acceptable excipients will be obvious to those skilled in the relevant art. Acceptable excipients include any inert, compatible substances added to make the final dosage forms, for the formulations, such as tablets, capsules, or soft gelatin capsules. For example, vegetable oil can be added as an excipient to make up the volume for the encapsulation of soft gelatin capsules. As such, a pharmaceutically acceptable excipient includes any excipients that are approved for use by the relevant authorities and are compatible with tocotrienols.




col is located in [NA] and he is available to meet: NO


Post reply
col

15.02.2008, 05:02
(edited by col, 15.02.2008, 05:34)

@ col

TOCO-8 - Study claims 42% hair growth in 5 months

If you read the MPB RESEARCH article:
CHRONIC INFLAMMATION, HAIR LOSS, AND WHAT YOU CAN DO ABOUT IT
http://www.hairloss-research.org/february1.html

You will see why Toco-8,combined with Curcumin (best form is BCM95/Biocurcumin)along with a DHT inhibitor could be quite useful:

--------------------------------------------------------------------

DHT inhibition- Finasteride, Saw Palmetto, Rivoflavin, Green Tea Extract, Copper, Peptides, and Topical Bayberry Extract.

PKC down regulation - Grape Seed Extract, Resveratrol, Vitamin E, Soy Isoflavones.

TNF-a down regulation- Curcumin, Ginkgo Biloba Extract, Stinging Nettle Extract, Green Tea Extract, Fish Oil, Borage Oil, Perilla Oil, and Topical Perilla leaf extract.

TGF down regulation- Curcumin, and topical Amacha.

--------------------------------------------------------------------




col is located in [NA] and he is available to meet: NO


Post reply
col

15.02.2008, 05:26

@ col

TOCO-8 - Study claims 42% hair growth in 5 months

Italian Patent Details Hair Growth Effects of Resveratrol/Curcumin Combination
http://www.hairloss-research.org/LinkUpdateResveratrol11-07.html

If you read the above article, it further confirms the possibility of using Curcumin for both TNF-a/TGF down regulation and Vitamin E (Toco-8)/Resveratrol for PKC down regulation.

A DHT inhibitor along with Curcumin & Toco-8 is a cheaper alternative to comply with their anti-inflammation protocol.

As Resveratrol can be quite expensive then a combo such as Greens First (a cheaper way of getting Resveratrol), which contains 100mg Resveratrol + 100mg decaff Green Tea, could be used along with Curcumin, in addition to a DHT inhibitor.


--------------------------------------------------------------------

DHT inhibition - Finasteride, Saw Palmetto, Rivoflavin, Green Tea Extract, Copper, Peptides, and Topical Bayberry Extract.

PKC down regulation - Grape Seed Extract, Resveratrol, Vitamin E, Soy Isoflavones.

TNF-a down regulation- Curcumin, Ginkgo Biloba Extract, Stinging Nettle Extract, Green Tea Extract, Fish Oil, Borage Oil, Perilla Oil, and Topical Perilla leaf extract.

TGF down regulation- Curcumin, and topical Amacha.

--------------------------------------------------------------------




col is located in [NA] and he is available to meet: NO


Post reply
col

15.02.2008, 07:30

@ col

TOCO-8 - Study claims 42% hair growth in 5 months

15 Feb 08

Fueling Testosterone and Preventing Hair Loss with Tocotrienols

Primordial Performance introduces Toco-8 -- a natural tocotrienol supplement designed to encourage testosterone production, while preventing hair loss.

http://www.prweb.com/releases/testosterone-boosting/hair-loss-protective/prweb699323.htm




col is located in [NA] and he is available to meet: NO


Post reply
col

15.02.2008, 07:39

@ col

TOCO-8 - Study claims 42% hair growth in 5 months

So TOCO-8 INCREASES Testosterone levels, hence DHT levels.

This has the OPPOSITE effect of Finasteride.

Any comments anyone ?




col is located in [NA] and he is available to meet: NO


Post reply
The Natural

15.02.2008, 11:37

@ col

TOCO-8 - Study claims 42% hair growth in 5 months

Col, great information on TOCO-8. It is something that I would definitely like to try in the near future.

When I posted that information on curcumin, the librarian Pete2 pooh poohed it; but I'll wait and see what he does now.

Have you looked into Maca root, as something to regulate the amount of estrogen in our bodies, thereby potentially increasing the amount of testosterone we can produce?




The Natural is located in [NA] and he is available to meet: NO

---
The Natural Internal Regimen

mornings - vitamin C + aged garlic extract; mid-mornings - curcumin (Meriva) + cayenne pepper/ginger; afternoons - algae extract; bedtime - MSM (OptiMSM)


Post reply
col

15.02.2008, 12:07
(edited by col, 15.02.2008, 12:39)

@ The Natural

TOCO-8 - Study claims 42% hair growth in 5 months

TN,

I already use Indole-3-Carbinol (I3C) very successfully to treat my Estradiol levels. Probably one of the most important products i use.

I have emailed my question about TOCO-8 increasing T, hence DHT, to the TOCO-8 manufacturers Primordial.

I really like the sound of TOCO-8 but the last thing i want is to increase my T levels.

Looking forward to their reply.

As for Curcumin, i am a strong believer in its abilities to treat various diseases although its effectiveness for hair-loss, (other than the Italian study and Hounty saying topical Curcumin completely stopped his hairloss) is still to be proved.

An excellent article regarding Curcumin appeared on LEF's website recently.
http://tinyurl.com/2ahpdo
It makes for very good reading.

I began using both LEF's BioCurcumin and the topical Psoria Gold curcumin cream last week .

I bought it because i thought it was a colourless Curcumin cream as opposed to the yellow HPL curcumin cream used by Hounty.

Unfortunately, its ALSO a yellow cream and almost 3x the price of HPL's cream. I use a soapy flannel to remove any yellow along my hairline immediately afterwards so its not a problem anyway :-)




col is located in [NA] and he is available to meet: NO


Post reply
col

15.02.2008, 13:41

@ col

TOCO-8 reply

Just received this reply from Primordial, manufacturers of TOCO-8, regarding my question on increased T leading to increased DHT:


15 Feb 08

Hello Col,

The main hook of the PR was the fact that you could actually do BOTH with a single natural nutrient. Despite a negligible increase in DHT (from possible T stimulation) the tocotrienols are still capable of protecting the hair and encouraging regrowth. Toco-8 may not be a total cure for all men who have alopecia or hypogonadism, but it is certainly a step in the right direction.

Primordial




col is located in [NA] and he is available to meet: NO


Post reply
The Natural

15.02.2008, 14:45

@ col

TOCO-8 - Study claims 42% hair growth in 5 months

Col,

Some argue that it's the excess estrogen that causes hair loss, and not the testosterone (which, in and of itself, is not a bad thing, right). Men need testosterone.




The Natural is located in [NA] and he is available to meet: NO

---
The Natural Internal Regimen

mornings - vitamin C + aged garlic extract; mid-mornings - curcumin (Meriva) + cayenne pepper/ginger; afternoons - algae extract; bedtime - MSM (OptiMSM)


Post reply
col

15.02.2008, 17:38

@ The Natural

TOCO-8 - Study claims 42% hair growth in 5 months

Yes, any hormonal imbalance can wreak havoc and cause alsorts of problems,including hairloss. For example, excess Estradiol also interferes with normal Thyroid function which can cause Hypothyroid which,in itself, can cause dry/brittle/thinning hair all over the scalp, not just the top.

As my Fin just doesn't work anymore then,logically, DHT is no longer the problem in my case hence my attack on both Estradiol & Inflammation. Once these are under control i believe the Fin will work as it did before. Most people seem to forget that the TWO known main causes for hair-loss are DHT AND Inflammation. BOTH must be kept under control.




col is located in [NA] and he is available to meet: NO


Post reply
Pete2

16.02.2008, 08:43

@ col

TOCO-8 - Study claims 42% hair growth in 5 months

» Yes, any hormonal imbalance can wreak havoc and cause alsorts of
» problems,including hairloss. For example, excess Estradiol also interferes
» with normal Thyroid function which can cause Hypothyroid which,in itself,
» can cause dry/brittle/thinning hair all over the scalp, not just the top.
»
» As my Fin just doesn't work anymore then,logically, DHT is no longer the
» problem in my case hence my attack on both Estradiol & Inflammation. Once
» these are under control i believe the Fin will work as it did before. Most
» people seem to forget that the TWO known main causes for hair-loss are DHT
» AND Inflammation. BOTH must be kept under control.




If you look at some of my older posts I was talking about the imbalance years ago. It is actually important to keep DHT in check as well as Estradiol.







Regards
Pete




Pete2 is located in [NA] and he is available to meet: NO


Post reply
superfred

17.02.2008, 07:47

@ Pete2

This is great regrowth..can we believe it ??

» » Yes, any hormonal imbalance can wreak havoc and cause alsorts of
» » problems,including hairloss. For example, excess Estradiol also
» interferes
» » with normal Thyroid function which can cause Hypothyroid which,in
» itself,
» » can cause dry/brittle/thinning hair all over the scalp, not just the
» top.
» »
» » As my Fin just doesn't work anymore then,logically, DHT is no longer
» the
» » problem in my case hence my attack on both Estradiol & Inflammation.
» Once
» » these are under control i believe the Fin will work as it did before.
» Most
» » people seem to forget that the TWO known main causes for hair-loss are
» DHT
» » AND Inflammation. BOTH must be kept under control.
»
»
»
»
» If you look at some of my older posts I was talking about the imbalance
» years ago. It is actually important to keep DHT in check as well as
» Estradiol.
»
»
»
»
»
»
»
» Regards
» Pete




superfred is located in [NA] and he is available to meet: NO


Post reply
debris

E-mail

17.02.2008, 09:24

@ superfred

This is great regrowth..can we believe it ??

increase in total hair count 42.4±40.9% (mean±SD)

that's a pretty huge sd

also they do not state if it was areata or mpb.

my conclusion is: probably just another scam.



debris has 1 Personal Journal(s). Click here to view
debris is located in [NA] and he is available to meet: NO


Post reply
superfred

17.02.2008, 10:05

@ debris

This is great regrowth..can we believe it ??

hmm...do you think a claim in such a patent is a lie ?




superfred is located in [NA] and he is available to meet: NO


Post reply
skiploss

17.02.2008, 10:09

@ superfred

This is great regrowth..can we believe it ??

» hmm...do you think a claim in such a patent is a lie ?

Scam. Notice the disclaimer at the bottom of their site. You can claim anything you want in a patent - a patent simply protects a product's design, it does not validate its efficacy. That is what the FDA is for.




skiploss is located in [NA] and he is available to meet: NO


Post reply
The Natural

17.02.2008, 12:38

@ skiploss

This is great regrowth..can we believe it ??

The FDA did not conclude that TOCO-8 was a "scam." YOU did.




The Natural is located in [NA] and he is available to meet: NO

---
The Natural Internal Regimen

mornings - vitamin C + aged garlic extract; mid-mornings - curcumin (Meriva) + cayenne pepper/ginger; afternoons - algae extract; bedtime - MSM (OptiMSM)


Post reply
Jtelecom

17.02.2008, 19:06

@ skiploss

This is great regrowth..can we believe it ??

» Scam. Notice the disclaimer at the bottom of their site. You can claim
» anything you want in a patent - a patent simply protects a product's
» design, it does not validate its efficacy. That is what the FDA is for.


You will see this same disclaimer on EVERY supplement. Your logic is a little fuzzy. I am not saying that this is or is not a scam, but the addition of the disclaimer means nothing. In fact, I believe that it may be required by law.




Jtelecom is located in [NA] and he is available to meet: NO

---
Jtelecom


Post reply
Jtelecom

18.02.2008, 00:38

@ Jtelecom

This is great regrowth..can we believe it ??

skiploss:

By the way, the identity of Maneless was posted about ten or eleven YEARS ago on Alt Baldspot. Most of us (unfortunate) veterans knew his identity or name a long, long time ago.




Jtelecom is located in [NA] and he is available to meet: NO

---
Jtelecom


Post reply
HanginInThere

Manila(UwishUrHere),
18.02.2008, 22:34

@ Jtelecom

This is great regrowth..can we believe it ??

» skiploss:
»
» By the way, the identity of Maneless was posted about ten or eleven YEARS
» ago on Alt Baldspot. Most of us (unfortunate) veterans knew his identity
» or name a long, long time ago.

is he a 40 yr old retarded virgin who lives with his mom




HanginInThere is located in MANILA(UWISHURHERE) and he is available to meet: YES
email hairsite@aol.com to arrange a meeting.

---
Recommended Hangin Regimen
Maxi Hair by Country Life 2/day
Saw Palmetto 320mg/day
Beta Sitosterol 125mcg/day
Pygeum 500/day
Nettles 500/day
Kal Amino Max 2/day


Post reply
The Natural

19.02.2008, 10:27

@ col

TOCO-8

As I've read, it seems to be tocotrienols, and not the tocopherols, that were able to produce the results mentioned in the study. There are other companies, like Jarrows, that make similar formulas. One, called TOCO-SORB, comes in capsule form, and contains more tocotrienols.




The Natural is located in [NA] and he is available to meet: NO

---
The Natural Internal Regimen

mornings - vitamin C + aged garlic extract; mid-mornings - curcumin (Meriva) + cayenne pepper/ginger; afternoons - algae extract; bedtime - MSM (OptiMSM)


Post reply
col

21.02.2008, 09:28

@ The Natural

TOCO-8

Interesting article.

Points out you need ALL 8 forms of Vitamin E.It increases sperm motility (good for finasteride users like myself) + "adding Vit E to cancer cells inhibits the production of the androgen receptor (AR)"



Why You Need Vitamin E for Prostate Health
http://www.prostate-massage-and-health.com/Vitamin-E.html

The reason Vitamin E supplements receive such big press is that our common foods are generally deficient in this vitamin. So, when we supplement and finally get enough of it, all kinds of "miraculous" things seem to happen.


A lot of people spend a lot of time and money in laboratories looking for prostate treatments that wouldn't be necessary if men were more properly nourished.

Many common prostate problems would be rare if our diets contained adequate nutritional elements. Prostate health would then be the norm for men of all ages.

Everyone has heard about Vitamin E and all of it's "miraculous" powers. The fact is, all the vitamins have "miraculous" powers. We would literally die without any one of them. They all perform various functions that create the miracle we know as life.

Vitamin E is very important in 2 specific roles in male health. Impotence and prostate cancer.


Let's Look At Impotence First

Deficiency of this vitamin causes loss of fertility in men. It is required for the formation of key sex hormones and enzymes responsible for sperm production. Deficiency inhibits the formation of sperm.

It may also aid in sperm mobility.


Lack of antioxidants (Vit E included) cause free radical damage to the cells of the body. The delicate wall of the sperm cell is highly succeptible to this kind of damage. This can cause infertility.

Vit E is a "free radical scavenger". It can prevent this damage. It increases the ability of sperm to fertilize an egg. The sperm become better able to attach to an egg.

In clinical study, men taking an E supplement for 3 months (400mg per day, natural, not synthetic) had sperm that were 2 1/2 times as potent as before the test began. (R. Bayer, "Treatment of Infertility with Vitamin E", Int J Fertil 1960; 5:70-78)

Another study in Saudi Arabia found that 20% of the men with low fertility, who were previously unable to conceive a child, became fathers!

Vit E is used up more quickly when consuming fish oils and vegetable oils. So, be sure to add Vitamin when using these oils.


Vitamin E and Prostate Cancer

Worldwide research shows the benefits of adding the correct type of Vitamin E to your diet to be amazing!

In a Clinical study by Dr. Demetrius Albanes, daily Vit E supplementation reduced prostate cancer by 32% and the death rate from prostate cancer by 41%. Pretty darn impressive!

In laboratory test by Dr. Qing Jiong, gamma tocopherol (one of the 8 natural forms of the vitamin. And, the form most present in our foods.) was shown to induce death in laboratory grown cancer cells while leaving healthy cells alone. It did this by interrupting spingolipid synthesis.

The study also showed that the anti-cancer effect was enhanced with the use of mixed tocopherols (containing gama tocopherol).

Research team led by Dr. Shuyuan Yeh found that Vit E caused a:


PSA Drop of As Much As 90%

With a decrease of 25% - 50% in the number of cancer cells. They found alpha-tocopherol-succinate to be most effective.

The researchers from New York's University of Rochester found that adding Vit E to cancer cells inhibits the production of the androgen receptor (AR) which is needed in order for prostate cancer cells to grow and develope.





------------------------------------------------------------------------------




The Type of Vitamin E That Is Effective
There are many forms of Vitamin E available in the stores and on line. Be sure to use natural form only. Stay away from all the synthetic forms. They do not give the results and they are all toxic. They are labeled dl-alpha-tocopherol not d-alphatocopherol (dl is synthetic).

It is better to use a Vitamin E Complex rather than a single form. Nature always works with nutrients in combinations. Hundreds of combinations. Never as isolates. Complex combinations is the way nutrients occur in nature.


There are 8 natural forms of Natural Vitamin E. D-alpha-tocopherol is the most common.

The test by Dr. Shuyuan Yeh used alpha-tocopherol-succinate.

The research done by Dr. Qing Jiong used gama-tocopherol. This form is not as commonly known. It was used most effectively in a mixed tocopherol combination.

Vitamin E is also an oil soluable vitamin. It requires fats for absorbtion. You need some fat in your meal to use this vitamin effectively. Fat free and extreme low fat diets deprive you of all the different oil soulable vitamins.

Although we commonly and effectively supplement with vitamins, it is best to make sure you also consume foods that are high in the complete natural nutrients you need. That way you receive the essential nutritional complexes (combinations).


Good and Bad
Natural Sources of Vitamin E
"Vegetable Oils" claim to be a good source of Vit E. You have probabally heard them called "poly-unsaturated" oils. Although these oils contain a small amount of the vitamin, they are dangerous to your health and not a good way to get the vitamin.

All commercial vegetable oils are highly processed. This renders them basically useless.

Cold pressed vegetable oils (with the exception of raw oilve and coconut) are very high in Omega 6 and Omega 9 fats. These "polyunsaturated oils" (Omega 6, and Omega 9) create dangerous amounts of free radicals and can greatly increase your cancer risk.

Raw fresh cold pressed wheat germ oil and fresh raw wheat germ are excellent natural sources of Vitamin E. Whole raw almonds, pecans, sunflower seeds, and avocado (California) are good also.

The best healthy source of natural Vit E and of gama-tocopherol is raw (cooking destroys and alters the vitamin) sesame seeds.



Be Well.....

William




col is located in [NA] and he is available to meet: NO


Post reply
col

21.02.2008, 09:31

@ col

TOCO-8

Vitamin E and Hair Loss
http://www.naturalhairlossremedies.com/vitamin-e-and-hair-loss.html

Vitamin E is important for healthy hair growth and reducing hair loss. Vitamin E can be found in avocados, nuts, seeds, and olive oil. Vitamin E increases oxygen uptake, which improves circulation to the scalp. It improves health and growth of hair. Since hair health is tied to the immune health, vitamin E is believed to stimulate hair growth by enhancing the immune function.

A Canadian physician who started going grey was able to reverse the process by taking 800iu of vitamin E in capsule form daily. At the age of 68 after some 15 years of taking vitamin E he still has a healthy head of thick black hair, and is the envy of men half his age.

Vitamin E has also been shown to retard the ageing process. It has been suggested that grey hair is a symptom of body degeneration so a supplement of vitamin E can only be beneficial whether you have grey hair or not.

The best natural sources of vitamin E are wheat germ, Soya beans, broccoli, brussel sprouts, spinach and eggs.




col is located in [NA] and he is available to meet: NO


Post reply
The Natural

21.02.2008, 10:21

@ col

TOCO-8

http://www.regrowhair.com/non-surgical-hair-loss-treatments/vitamin-e-for-hair-loss/




The Natural is located in [NA] and he is available to meet: NO

---
The Natural Internal Regimen

mornings - vitamin C + aged garlic extract; mid-mornings - curcumin (Meriva) + cayenne pepper/ginger; afternoons - algae extract; bedtime - MSM (OptiMSM)


Post reply
The Natural

01.04.2008, 16:04

@ col

Curcumin w/Bioperine

Quick note on curcumin:

While I have read much to the contrary, I did come across a site (www.turmeric-curcumin.com) that states, "The use of the chemical piperine from pepper, trade-named Bioperine, was a poor attempt at increasing bioavailability at the expense of the epithelial lining of the stomach, small intestine and bowels... If you want to use capsules, make certain they DO NOT contain a pepper extract that is advertised to improve bioavailability."




The Natural is located in [NA] and he is available to meet: NO

---
The Natural Internal Regimen

mornings - vitamin C + aged garlic extract; mid-mornings - curcumin (Meriva) + cayenne pepper/ginger; afternoons - algae extract; bedtime - MSM (OptiMSM)


Post reply
The Natural

01.04.2008, 17:46

@ col

Italian Hair Supplement

Here is where you can buy the Italian hair supplement of Curcumin & Resveratrol, called "Capsures:" http://www.corpo-sano.net/en/hair-supplements.html#Capsures%20-%20Hair%20Supplements

Looks expensive, though.




The Natural is located in [NA] and he is available to meet: NO

---
The Natural Internal Regimen

mornings - vitamin C + aged garlic extract; mid-mornings - curcumin (Meriva) + cayenne pepper/ginger; afternoons - algae extract; bedtime - MSM (OptiMSM)


Post reply
randle20

02.04.2008, 08:10

@ The Natural

Italian Hair Supplement

» Here is where you can buy the Italian hair supplement of Curcumin &
» Resveratrol, called "Capsures:"
» http://www.corpo-sano.net/en/hair-supplements.html#Capsures%20-%20Hair%20Supplements
»
» Looks expensive, though.

The Natural, I have been reading alot about the TOCO -8. How is your regimin working for you? I have been taking SAW P along with some vitamins. I feel as if it maybe helping a little, but im still shedding.

This is a picture of my thinning problem.
http://good-times.webshots.com/photo/2843026360103282845aHyXuY




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Post reply
Goingallout

02.04.2008, 09:46

@ randle20

Italian Hair Supplement

» » Here is where you can buy the Italian hair supplement of Curcumin &
» » Resveratrol, called "Capsures:"
» »
» http://www.corpo-sano.net/en/hair-supplements.html#Capsures%20-%20Hair%20Supplements
» »
» » Looks expensive, though.
»
» The Natural, I have been reading alot about the TOCO -8. How is your
» regimin working for you? I have been taking SAW P along with some
» vitamins. I feel as if it maybe helping a little, but im still shedding.
»
» This is a picture of my thinning problem.
» http://good-times.webshots.com/photo/2843026360103282845aHyXuY

Thanks for providing the picture, Randle. Let me give you my two cents on what you need to do, given your loss situation.

You need to curb your DHT-related hair loss powerfully and quickly. I'd use finasteride or dutasteride. Saw Palmetto and Betasitosterol can work somewhat IMO, but I think you need industrial grade help (and I say this even though I am thinking of stopping using Dutasteride because of the side effects). You also need regrowth to happen before the follicles of hair you've already lost die for good: Minoxidil 5% for that. You need to stop inflammation (which sometimes you can't even feel): avoid sugars, breads, pastas and stick with meat and vegetables. Take plenty of fish oil; several grams a day. Look at posts on this site by Hogan38; he had some advice on which oils to take instead of or perhaps in addition to fish oil.

Good luck. Damn these baldness genes we got from our parents!




Goingallout is located in [NA] and he is available to meet: NO


Post reply
The Natural

02.04.2008, 09:50

@ randle20

Italian Hair Supplement

Randle,

I am not a big fan of multi-vitamins, unless you have a real deficiency. And I do not think that Saw Palmetto, by itself, will prevent further thinning.

The clinical studies provided by Col look promising, indeed, primarily because they are specific to our cause, namely, to stop thinning (and regrow hair). I am going to wait a couple of months before posting my progress with this regimen, just to be sure.

It would be great if we could establish "a control group of posters" here at Hairsite, and then report our findings.




The Natural is located in [NA] and he is available to meet: NO

---
The Natural Internal Regimen

mornings - vitamin C + aged garlic extract; mid-mornings - curcumin (Meriva) + cayenne pepper/ginger; afternoons - algae extract; bedtime - MSM (OptiMSM)


Post reply
The Natural

03.04.2008, 13:51
(edited by The Natural, 03.04.2008, 14:34)

@ col

Curcumin

Note to those using Super-Bio Curcumin: It has been receiving some negative feedback in different forums "unrelated" to hair loss: http://myelomahope.blogspot.com/2008/02/regimen-correction.html




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The Natural Internal Regimen

mornings - vitamin C + aged garlic extract; mid-mornings - curcumin (Meriva) + cayenne pepper/ginger; afternoons - algae extract; bedtime - MSM (OptiMSM)


Post reply
The Natural

03.04.2008, 13:57

@ col

Canadian Herbal Supplement

Here is a herbal supplement with Curcumin, Resveratrol, and other treats: http://www.nationalnutrition.ca/detail.aspx?ID=2795




The Natural is located in [NA] and he is available to meet: NO

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The Natural Internal Regimen

mornings - vitamin C + aged garlic extract; mid-mornings - curcumin (Meriva) + cayenne pepper/ginger; afternoons - algae extract; bedtime - MSM (OptiMSM)


Post reply
randle20

03.04.2008, 23:00

@ The Natural

Canadian Herbal Supplement

» Here is a herbal supplement with Curcumin, Resveratrol, and other treats:
» http://www.nationalnutrition.ca/detail.aspx?ID=2795

THe natural, Thats great. How long have you been taking the TOCO8, and I know you want to wait a few months, but have you noticed anything at all from the start?

Im probably going to drop the SP soon.




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Post reply
The Natural

04.04.2008, 11:33

@ randle20

Canadian Herbal Supplement

Randle,

I have been taking TOCO-SORB by Jarrow for a little over a month. Added the curcumin and resveratrol recently.

Let's wait until June/July before I detail my "results." As you've read, the studies themselves took at least this long. A one or two month assessment will not help you or anyone else, IMHO.




The Natural is located in [NA] and he is available to meet: NO

---
The Natural Internal Regimen

mornings - vitamin C + aged garlic extract; mid-mornings - curcumin (Meriva) + cayenne pepper/ginger; afternoons - algae extract; bedtime - MSM (OptiMSM)


Post reply
The Natural

04.04.2008, 12:11

@ The Natural

Curcumin Absorption

This is from Dr. Ray Sahelian:

Q. It is my understanding, that based on prior research, that curcumin bioavailability is compromised and in turn the absorption and therapeutic blood levels are low. I also understand that various research trials are demonstrating the concurrent use of piperine, which enhances the absorption and bioavailability. I am curious if your research supports this as well and if there is any further information that you might have to support this fact.


A. We have not seen convincing research that indicates piperine is needed for curcumin absorption or bioavailability. Almost all studies with curcumin have not used any piperine, therefore we tend to understand that curcumin works well by itself.




The Natural is located in [NA] and he is available to meet: NO

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The Natural Internal Regimen

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Post reply
The Natural

05.04.2008, 09:16

@ col

KAL herbs Turmeric/Resveratrol

http://www.vitaminshoppe.com/store/en/browse/sku_detail.jsp?id=KA-1973&srccode=cii_10043468&cpncode=12-45825909-2&source=SZKA-1973




The Natural is located in [NA] and he is available to meet: NO

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Post reply
The Natural

13.04.2008, 13:15

@ col

Too Many Antioxidants

I have noticed that the dosage recommended on herbal bottles is twice as much as was used in the aforementioned studies on curcumin/resveratrol. Perhaps there is a reason why the testers used a much lower dosage:


Can you get too many antioxidants?

"When we hear the word "antioxidants," many of us automatically think how good they are for us. In our minds, antioxidants are the good guys. We may not be exactly sure what they do, but the "anti" in their name tells us that they protect us by fighting off something bad. And if they're the good guys fighting the bad guys, how could we possibly get too many?

On top of the good guys versus bad guys perspective, we also know that many antioxidants are vitamins - vitamins as familiar to us as A and C and E - and minerals such as zinc and selenium. And that these are nutrients that we know are of benefit to our health (There are other antioxidants, though, that are not nutrients at all, but rather compounds in our bodies with various physiological function; for example, uric acid and ceruloplasmin are two of the key antioxidants found in our bloodstream.)

Yet, it turns out that it is just the black and white story that if antioxidants are good for us, then more is better. Like an orchestra that needs the correct representation of instruments to make a beautiful symphony, our bodies need an array of antioxidants, not just this one or that one, to create harmony in our health."




The Natural is located in [NA] and he is available to meet: NO

---
The Natural Internal Regimen

mornings - vitamin C + aged garlic extract; mid-mornings - curcumin (Meriva) + cayenne pepper/ginger; afternoons - algae extract; bedtime - MSM (OptiMSM)


Post reply
The Natural

13.04.2008, 13:22

@ col

High Doses of Antioxidants

"During the 1990's, researchers began to conduct very large-scale studies (involving tens of thousands of participants) to determine the benefits of antioxidants in fairly high doses. The Alpha-Tocopherol, Beta-Carotene, and Cancer prevention study (ATBC), the Physicians' Health Study (PHS), the Beta-Carotene and Retinol Efficacy Trial (CARET), and the Skin Cancer Prevention Study (SCPS) were among these large-scale studies. One very unexpected result in several of these studies was the fact that antioxidant dietary supplements actually increased the risk of disease instead of lowering it. In fact, some studies were abruptly canceled, with letters being sent to participants, explaining that antioxidant supplementation seemed to be putting them at greater health risk. While many of these studies have been criticized, and their results debated among scientists, this decade of research changed our thinking about antioxidants and their health role. What we are now realizing is that it is not just antioxidants working in isolation that have benefits but that antioxidants need each other to function optimally and promote our optimal health.

The problem with thinking about antioxidants as "good guys" is that every antioxidant can become a prooxidant, i.e., it can reverse its role in our metabolism. In chemical terms, when a substance functions as an antioxidant, what it does it give away an electron. Electron-give-away is what antioxidants do. (This potential power for giving away electrons is called reduction potential).

What's so good about a compound that gives away electrons is that it can donate it to a "reactive" substance that is in need of one since substances in our body can become far too reactive when they are left with an uneven number of electrons. (Electrons like to exist in pairs, and don't like being "unpaired";). One leftover electron is enough to cause trouble.

When a substance has a leftover electron and becomes too reactive, it can damage anything nearby, including the wall of a blood vessel or the membrane of a cell. (Highly reactive substances that cause damage to body parts include a group of substances you may already be familiar with, called free radicals). If these highly reactive substances can just get hold of one additional electron, they can be quieted and potential damage can be avoided. That's what's so good about antioxidants that give away electrons.

However, when an antioxidant gives away an electron, another problem occurs. The antioxidant itself becomes a radical, because it now has a leftover electron. When vitamin C (ascorbic acid) acts as an antioxidant and gives away an electron, it becomes vitamin C radical (ascorbyl radical). It's no longer helpful to us as an antioxidant (or a vitamin) in this form. Like all radicals, we don't want excessive amounts of ascorbyl radical in our body. But what's the solution?"




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The Natural Internal Regimen

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Post reply
The Natural

14.04.2008, 14:30

@ The Natural

Too Many Antioxidants

Antioxidants by Ray Sahelian, M.D.,

Q: Is it possible to take too many antioxidants?

A. Yes, it is possible to take too many antioxidants. Free radicals may be needed for certain functions, such as fighting certain germs or infections.


www.raysahelian.com/antioxidant.html




The Natural is located in [NA] and he is available to meet: NO

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The Natural Internal Regimen

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Post reply
The Natural

14.04.2008, 14:32

@ The Natural

Too Many Antioxidants

Some Good Things to Say About Free Radicals



Copyright ©1995 by Jack Challem
Reproduced from The Nutrition Reporter™ newsletter.
All rights reserved.





"I've been taking vitamin supplements since 1969 -more than a quarter-century- and writing about them for health magazines since 1974. I interview some of the best vitamin docs in the world, read medical journals and nutrition books, and have even written a couple, too. Though I succumb to an occasional cheeseburger, my diet has been generally good, with the overall emphasis on wholesome foods.


You could say I was an "early adopter" of the antioxidant craze. Until a year ago, I included in my daily regimen 1,600 IU of vitamin E, 100,000 IU of mixed beta- and alpha-carotene, and about 15 grams of vitamin C. High doses-but after all, I should know what I'm doing. Right?


Not necessarily. With all the attention given to antioxidants, a lot of questions still remain unanswered. How much is enough? How much is too much? And are free radicals really all that bad?


I began asking these questions in 1994 because the vitamins I took should have left me feeling absolutely energized. That's what the research says. And what the advertising for antioxidant supplements often suggests. But over the past 10 years or so, I've felt far more fatigued than I should have. Tired in the morning. Tired in the afternoon. Tired in the evening but, I should note, not suffering from crippling Chronic Fatigue Syndrome.


It wasn't easy finding the answers. But I eventually tracked down the person who would know them: Denham Harman, M.D., Ph.D. He's the fellow who conceived the free radical theory of aging back in November 1954.


To my surprise, I discovered that I was doing too good of a job quenching those dangerous free radicals we all hear about. I was taking too many antioxidants. I imagined myself at a meeting of Antioxidants Anonymous and confessing, "My name is Jack C. and I began taking antioxidants at the age of nineteen..."


With all the talk about the anti-aging and anti-disease benefits of antioxidants, we too easily forget about the essential role of free radicals. That's right-free radicals are essential for health. Of course, many people (like me) reasonably argue that most people are exposed to far too many free radicals and need to boost their antioxidant intake for protection. But there are dangers, I found, in simplifying the issue of free radicals and antioxidants to one of a biochemical gunfight at the OK Corral.


Free radicals, of course, are molecules with unpaired electrons aggressively looking for a mate. Oxygen free radicals are particularly dangerous because they react readily with other molecules. When they find a mate-just about anything will do-they can oxidize cell membranes and cholesterol and disrupt deoxyribonucleic acid (DNA) in ways that accelerate aging and lead to cancer.


Cigarette smoke, air pollution, exposure to sunlight, radiation, pesticides, some drugs, and chemotherapic agents produce free radicals. So do polyunsaturated fats. If you live at a high altitude or fly frequently, you have to deal with large numbers of free radicals because of the higher levels of gamma-ray radiation. (Thicker air at lower altitudes absorbs the radiation and reduces exposure.) Even over-exercising generates extra free radicals.


But the biggest source of free radicals is our own bodies. Why on Earth would we produce the very seeds of our destruction? There are some very good reasons that you generally don't hear about. White blood cells use free radicals to destroy bacteria and virus-infected cells. According to Bruce Ames, Ph.D., of the University of California, Berkeley, these free radicals prevent immediate death from infection. In addition, with the help of other free radicals, the liver's cytochrome P-450 enzymes detoxify harmful chemicals, again, protecting us from a quick death.


Free radicals are also a normal byproduct of everyday respiration-breathing-in which our bodies use oxygen and generate energy. The process of creating energy, called bioenergetics or oxidative phosphorylation, is reminiscent of the childhood game "hot potato." Molecules get passed around, as the cell tries to keep the good ones and getting rid of the bad ones.


The sheer scale of this activity is a mind-blower. Ames has estimated that each cell in the body suffers 10,000 free radical "hits" each day. The body's own antioxidants, such as superoxide dismutase and glutathione, form the foundation of an exquisit defense against free radicals. But this defense isn't perfect. That's why free radical damage-oxidation-accumulates. It turns good cholesterol bad, causes cataracts, contributes to Alzheimer's disease, and leads to cancer. Underscoring all of these changes, free radicals age us, sometimes gracefully, sometimes not.


In talking with Harman, I learned that the relationship between free radicals and antioxidants was really one of balance. Now "retired" and professor emeritus of medicine at the University of Nebraska, Omaha, Harman spends at least five full days each week in his office and regularly publishes articles in medical journals. He has a lot of energy for a man about to turn 80.


Harman's scientific papers are a joy to read, and he can explain complex processes clearly to non-scientists. His early papers on free radicals and antioxidants have an almost religious or metaphysical quality. Harman was, after all, discussing life and death, though on molecular and cellular levels. He also pointed out that free radical chemical reactions likely led to the first life on Earth and, subsequently, to the evolution of species by prompting DNA mutations. Pretty heady stuff.


In one of our phone conversations, I asked Harman which supplements he took. Unlike a lot of doctors who don't want to go on record revealing this information, Harman was forthright: 400 IU. vitamin E, 2,000 mg. vitamin C, 100 mcg. selenium, and 30 mg. coenzyme Q10 each day and 25,000 IU of beta-carotene every other day.
"I'd take more," he said, "but I can't afford to be fatigued."


My ears perked up. "Fatigued?" I asked.


Harman explained that excessive antioxidants could cause fatigue and muscle weakness. Several years ago, in an experiment, Harman and his colleagues found that large amounts of butylated hydroxytoluene (BHT), a synthetic antioxidant, interfered with the ability of mice to produce energy. Although the amount was of BHT was equivalent to 7.5 pounds in a human adult, Harman feels that people can still overdo antioxidants.


"Too many antioxidants can leave you feeling very weak," Harman said. "BHT decreases ATP and mitochondria function." ATP, or adenosine triphosphate, is essential for energy production in the mitochondria, the part of the cell biologists describe as the "energy factory."


I asked Harman whether too many natural antioxidants could also cause fatigue. I was thinking about the 1,600 IU of vitamin E and 100,000 IU of beta-carotene I had been taking for at least 10 years.


Harman was unequivocal. Yes. Just as some experiments have shown that vitamin E supplements increase stamina, there's a point of diminishing returns. And I had inadvertently hit that point.


Over the years I had upped my vitamin E and beta-carotene intake a little at a time. Like other people, I don't relish the though of cancer and I want to do everything reasonably possible to protect myself. Antioxidants provide some of that protection. I also knew that our bodies become less efficient metabolically as we age and that our need for micronutrients increases with age.


But after weighing what Harman told me, I decided to reduce my vitamin E supplements from 1,600 IU to 800 IU daily and my mix of beta- and alpha-carotene to 50,000 IU. Within a day or two, my energy levels were up-way up-an almost anti-climactic ending to my story. I still don't like getting up in the morning, but I do get up without feeling fatigued. Nor do I need a nap in the afternoon or early evening.


Now that I've sacrileged the shrine of antioxidants, the inevitable questions arise. First, should you take antioxidants? Unquestionably, yes. How much vitamin E and other antioxidants should you take? There's no simple answer. The traditional, and low, Recommended Dietary Allowances (RDAs) are in a state of flux and will probably be revised upward. Last year, the nonprofit Alliance for Aging Research, based in Washington, D.C., recommended that generally healthy people take antioxidant supplements in the following daily ranges:



vitamin E, 100-400 IU,

vitamin C, 200-1,000 mg., and

beta-carotene, 17,500-50,000 IU.

To decide how much of these antioxidants you should take, weigh the free radical stresses you face. Do you live in a large, polluted city? Do you smoke or live with a smoker? Do you live at a high altitude or spend a lot of time in the sun? Do you eat refined foods with polunsaturated fats (from which the vitamin E has been removed)? The more of these questions you say "yes" to, the higher your antioxidant intake should probably be.


Ultimately, of course, you have to listen to your body and determine the dose you feel better at, or worse, and adjust it accordingly. By all means, take more if you feel better-or if a physician suggests that you do so. However, if you're really studious about your diet, eat organic foods, are relatively young, and in good health, you may not need a lot of supplemental antioxidants. One more point to consider: Harman contends that the downward slide begins at age 27, meaning this is when you really need to start protecting yourself against the growing free radical cascade in your body.


The key, as I learned from Harman, is to take enough antioxidants to slow the aging process and stave off degenerative diseases, but not so much that you're fatigued. To a certain extent, you have to trust that what you're doing is right because the consequences of not taking antioxidants may take years to appear. It's sort of like brushing your teeth; you do it because you don't want to face the consequences of not brushing.


There are other important lessons here, and they relate to how antioxidants have become the 20th century's embodiment of the age-old fountain of youth. From time to time, I think of a conversation I had with Hal Huggins, D.D.S., a nutritionally oriented dentist in Colorado Springs, Colo. In the early 1980s, after working with him on a magazine article, I asked him to comment on a blood analysis obtained by my regular doctor. Based on my cholesterol level, the computerized analysis stated that I had a 6 percent risk of dying from heart disease over the next few years. Huggins looked at the risk assessment and though for a moment. "You know, Jack, there's no way you're going to get out of this life alive," he said. "Odds are that you'll eventually die of heart disease or cancer. But you're going to die of something."


Some of the ads for antioxidants may leave you thinking that you'll manage to get out of this life alive. Antioxidants can help you live longer and healthier-Harman, Ames, and many other scientists are convinced of this. But antioxidants won't grant you immortality. And very high intake of antioxidants, apparently, can sometimes sap enough energy to prevent you from enjoying those extra years.


In my mid 40s, I now have more energy than I've had in years. Striking a balance between free radicals and antioxidants has made good sense for my health. It has also helped me recognize my fundamental mortality. It's an important lesson, and I'll remember it."


All the best to you,
Jack Challem
The Nutrition Reporter™





The information provided by Jack Challem and The Nutrition Reporter™ newsletter is strictly educational and not intended as medical advice. For diagnosis and treatment, consult your physician.




The Natural is located in [NA] and he is available to meet: NO

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The Natural Internal Regimen

mornings - vitamin C + aged garlic extract; mid-mornings - curcumin (Meriva) + cayenne pepper/ginger; afternoons - algae extract; bedtime - MSM (OptiMSM)


Post reply
The Natural

21.04.2008, 14:00

@ col

The dosage

500 mg. of curcumin (concentrate)
100 mg. of resveratrol
60 mg. of tocotrienols (high absorption)

For me, this means only three capsules per day (though the bottles may recommend twice as much).




The Natural is located in [NA] and he is available to meet: NO

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The Natural Internal Regimen

mornings - vitamin C + aged garlic extract; mid-mornings - curcumin (Meriva) + cayenne pepper/ginger; afternoons - algae extract; bedtime - MSM (OptiMSM)


Post reply
cal

22.04.2008, 22:56

@ The Natural

The dosage

about Circumin & ARs in general:


How is any of the systemic stuff gonna target the scalp skin alone?

Wouldn't all these systemic method of reducing AR activity (the Vitamin E thing for example) just be a more roundabout way of functionally decreasing all your androgens in your system?

Popping pills to affect ARs in some way . . . it all sounds kind of like just a different way to get the effects of oral Spiro to me. No thanks.




cal is located in [NA] and he is available to meet: NO


Post reply
HairSite Admin

Homepage

24.04.2008, 15:02

@ The Natural

The 5AR inhibitor and other effects of curcumin

C urcumin has a number of biological actions in addition to being an anti-oxidant. It also inhibits 5a-reductase, which converts testosterone
to 5a-dihydrotestosterone.

The other actions -

Antibacterial
Antiprotozoan
Antiviral
Hypolipemic
Hypoglycemic
Anticoagulant
Antioxidant
Antitumour
Anticarcinogenic

www.ias.ac.in/currsci/jul102004/44.pdf









» 500 mg. of curcumin (concentrate)
» 100 mg. of resveratrol
» 60 mg. of tocotrienols (high absorption)
»
» For me, this means only three capsules per day (though the bottles may
» recommend twice as much).




HairSite Admin is located in [NA] and he is available to meet: NO

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email: hairsite@aol.com for free consultations
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Post reply
The Natural

24.04.2008, 18:08

@ cal

The dosage

» a...way of functionally decreasing all your androgens in your system?

All? Not all.

» Popping pills to affect ARs in some way . . . it all sounds kind of like
» just a different way to get the effects of oral Spiro to me. No thanks.

Oral Spiro? Heaven forbid!

No thanks? That just means more wine, curry, and fruit for the rest of us!

;-)




The Natural is located in [NA] and he is available to meet: NO

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mornings - vitamin C + aged garlic extract; mid-mornings - curcumin (Meriva) + cayenne pepper/ginger; afternoons - algae extract; bedtime - MSM (OptiMSM)


Post reply
The Natural

30.04.2008, 08:52

@ col

One month results: Scalp condition

I am no longer experiencing any dandruff.




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Post reply
The Natural

06.05.2008, 08:41

@ The Natural

Curcumin Absorption: The Tragedy of Tumeric

The Tragedy of Tumeric For Hairloss




From: The New Straits Times
04-28-08

TUMERIC is a very important in Ayurvedic medicine, the 5,000- year-old Indian healing system. It has been used through the ages as an "herbal aspirin" and "herbal steroid" to relieve swelling and pain.

The Materia Medica, a standard Ayurdevic reference, cites dozens of conditions in which turmeric can be helpful as an add on therapy for many ailments, including tissue injury and pain.

According to Mark Blumenthal, executive director of the American Botanical Council based in Austin, Texas, "The high degree of reverence for turmeric is evidenced by the fact that it is used in nearly all Asian cultures".

Turmeric is a very powerful, anti-inflammatory agent. It would be useful for any condition that is accompanied by pain and swelling. Taken orally, turmeric inhibits the response of the body to inflammation and pain causing agents both directly and indirectly.

It stimulates the production of natural steroid (corticosteroids) from the adrenal glands. They also make the cortisone receptor sites on cells more sensitive and prevent the breakdown of cortisol (the body's own natural steroid). This has a powerful effect on reducing swelling and reducing pain.

In fact, curcumin (one of the active molecules of turmeric) has been found to be every bit as effective as the pharmaceutical drugs cortisone, indometacin and phenylbutazone in clinical trials.

The anti-inflammatory effects are comparable in effectiveness to pharmaceutical drugs (such as phenylbutazone and indomethacin) but without the serious side effects.

Turmeric extracts prevented the synthesis of inflammatory chemicals in the body in a clinical trial of patients with rheumatoid arthritis.

Turmeric lowered concentration of the hormone-like substances responsible for the inflammation in arthritis and lessened the severity of morning stiffness, joint pain, and walking difficulty.

Despite all this good news, there is one very big tragedy with turmeric. It is poorly absorbed. In fact, less than one per cent of the oral dose actually gets into the blood.

"Nearly, all the effect of turmeric are on the walls of the intestines as hardly anything gets absorbed," said Dr Gulam Nabi Qazi, director of the Indian Institute of Integrative Medicine.

However, new extraction technology and the use of an oligosaccharide molecule now makes it possible for the turmeric extracts to be absorbed by up to 1,000 times.

The new technology increases solubility. This makes it possible to obtain fast action on inflammatory symptoms by guaranteeing bio equivalence of 1,200 mg/day (therapeutic daily dosage).

The new high blood levels of turmeric represents an advance over steroids, analgesics (paracetamol), non-steroidal anti-inflammatory drugs and painful Intra articular injection with steroids, and hyaluronic acids.

Sufficient dose levels can now be introduced into the blood. This allows for high level of composition in curcuminoids - vital to the anti-inflammatory effects. The new turmeric extract has an activity comparable to non-steroidal anti-inflammatory drugs without any side effects.

More importantly, it helps prevent cartilage degeneration - the cost of long term pain, disability and disfigurement in arthritis.

The Australian Therapeutic Goods Administration allows a claim of "may be used for the treatment of acute and chronic arthritic pain".

Professor Yves Henrotin, who is the Director of the Bone and Cartilage Research Unit at the University of Liege, Belgium sees this as a big new possibility, especially since there has been no real new innovation in the non-steroidal anti-inflammatory drug market globally.

The professor, who is in Malaysia now to meet opinion leaders and deliver a series of public lectures, said the turmeric extract delivers complete inflammatory mediators inhibition in the following ways and comparable to the most sophisticated pharmaceutical drugs:

* Inhibition of Cyclooxygenase and PE 2 production
* No inhibition of prostacyclines
* Inhibition of NO (Oxidative stress)
* Inhibition of pro-inflammatory cytokine
* Datuk Dr Rajen M. is a pharmacist with a doctorate in holistic medicine



Editor’s Note:

Curcumin has such potent therapeutic properties that even the miniscule absorption of whole tumeric, such as that used in the patented oral hair loss treatment, “Capsures” (Resveratrol Curcumin combination) was found to have hair growth promoting effects. This hair growth promoting effect, while not definitively known, is likely due to the release of Substance P.

Most commercially available preparations of curcumin have very poor bioavailability, impairing their ability to confer hair growth properties. Scientists have recently discovered a novel curcumin preparation with exceptional bioavailability. In a human study, this advanced curcumin preparation—termed BCM-95®—delivered up to seven times more curcumin to the bloodstream than a standard curcumin product. This increased bioavailability should greatly enhance curcumin’s benefits.

At MPB Research we utilize BCM-95, called “Super Bio-Curcumin” mentioned above , which results in higher and longer sustained blood levels. In fact each 400 mg capsule contains the equivilant of 2772 mg of commercially available 95% Curcumin extracts.

Capsures, the patented Resveratrol/Curcumin combo from Italy uses 82.4mg of a 95% Extract of Curcumin per capsule, 4 times a day, for a total of 350mg. Super Bio-Curcumin gives you their equivilant of 2772mg , which gives more benefits and is far more cost effective.




The Natural is located in [NA] and he is available to meet: NO

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The Natural Internal Regimen

mornings - vitamin C + aged garlic extract; mid-mornings - curcumin (Meriva) + cayenne pepper/ginger; afternoons - algae extract; bedtime - MSM (OptiMSM)


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p_rry

Homepage E-mail

06.05.2008, 13:34

@ The Natural

toco-8

I tried to order some of it, but it costs $20 to ship to Thailand. Maybe I'll wait until I'm in the states again.




p_rry is located in [NA] and he is available to meet: NO


Post reply
The Natural

06.05.2008, 13:57

@ p_rry

toco-8

Perry, I am using Jarrow's TOCO-SORB. It's very good.




The Natural is located in [NA] and he is available to meet: NO

---
The Natural Internal Regimen

mornings - vitamin C + aged garlic extract; mid-mornings - curcumin (Meriva) + cayenne pepper/ginger; afternoons - algae extract; bedtime - MSM (OptiMSM)


Post reply
p_rry

Homepage E-mail

06.05.2008, 14:31

@ The Natural

toco-8

oh cool, I'll have to check out the shipping on that company. Thanks.




p_rry is located in [NA] and he is available to meet: NO


Post reply
The Natural

06.05.2008, 15:59

@ p_rry

toco-8

» oh cool, I'll have to check out the shipping on that company. Thanks.

Yes, please do. And iHerb.com sells TOCO-SORB at almost half the price as my local nutrition store.




The Natural is located in [NA] and he is available to meet: NO

---
The Natural Internal Regimen

mornings - vitamin C + aged garlic extract; mid-mornings - curcumin (Meriva) + cayenne pepper/ginger; afternoons - algae extract; bedtime - MSM (OptiMSM)


Post reply
helpme23

07.05.2008, 07:30

@ The Natural

toco-8

Hi Guys

I have just ordered TOCO-8, I have a receeding hairline and I am desperate to stop it going any further, I have tried fin but got sides after just two weeks so I have decided to quit it. I was also using rogain foam but that only seemed to make my hairline worse. I am looking for a natural alternative. Judging by the above comments on curcumin and reservatol would this be the right product to take along with TOCO-8?

http://www.tattvasherbs.com/turmericplus.htm

Thanks




helpme23 is located in [NA] and he is available to meet: NO


Post reply
The Natural

07.05.2008, 18:49

@ helpme23

toco-8

» Hi Guys
»
» I have just ordered TOCO-8, I have a receeding hairline and I am desperate
» to stop it going any further, I have tried fin but got sides after just two
» weeks so I have decided to quit it. I was also using rogain foam but that
» only seemed to make my hairline worse. I am looking for a natural
» alternative. Judging by the above comments on curcumin and reservatol would
» this be the right product to take along with TOCO-8?
»
» http://www.tattvasherbs.com/turmericplus.htm
»
» Thanks

Helpme23, that's a good find. It's cheaper than Life Extension's:

http://www.iherb.com/ProductDetails.aspx?c=1&pid=1991456822181762381

I am using Jarrow's now, but I may switch to one these.




The Natural is located in [NA] and he is available to meet: NO

---
The Natural Internal Regimen

mornings - vitamin C + aged garlic extract; mid-mornings - curcumin (Meriva) + cayenne pepper/ginger; afternoons - algae extract; bedtime - MSM (OptiMSM)


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