Hair Loss - Dutasteride versus finasteride

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HairSite Admin

09.05.2008, 22:57

Dutasteride versus finasteride (Propecia, Avodart, Spiro, DHT & hormones ...)
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J Am Acad Dermatol. 2006 Dec;55(6):1014-23

The importance of dual 5alpha-reductase inhibition in the treatment of male pattern hair loss: results of a randomized placebo-controlled study of dutasteride versus finasteride

BACKGROUND:
Male pattern hair loss (MPHL) is a potentially reversible condition in which dihydrotestosterone is an important etiologic factor.

OBJECTIVE:
Our aim was to evaluate the efficacy of the type 1 and 2 5alpha-reductase inhibitor dutasteride in men with MPHL.

METHODS:
Four hundred sixteen men, 21 to 45 years old, were randomized to receive dutasteride 0.05, 0.1, 0.5 or 2.5 mg, finasteride 5 mg, or placebo daily for 24 weeks.

RESULTS:
Dutasteride increased target area hair count versus placebo in a dose-dependent fashion and dutasteride 2.5 mg was superior to finasteride at 12 and 24 weeks. Expert panel photographic review and investigator assessment of hair growth confirmed these results. Scalp and serum dihydrotestosterone levels decreased, and testosterone levels increased, in a dose-dependent fashion with dutasteride.

LIMITATIONS: The study was limited to 24 weeks.

CONCLUSION: Dutasteride increases scalp hair growth in men with MPHL. Type 1 and type 2 5alpha-reductase may be important in the pathogenesis and treatment of MPHL.

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brm

his room,
11.05.2008, 23:10

@ HairSite Admin
Dutasteride versus finasteride
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Total testosterone may not be the real stake. rather free T. And they say nothing about this.

brm is located in HIS ROOM and he is available to meet: YES
email hairsite@aol.com to arrange a meeting.

HairSite Admin 09.05.2008, 22:57	Dutasteride versus finasteride (Propecia, Avodart, Spiro, DHT & hormones ...) Post reply
	J Am Acad Dermatol. 2006 Dec;55(6):1014-23 The importance of dual 5alpha-reductase inhibition in the treatment of male pattern hair loss: results of a randomized placebo-controlled study of dutasteride versus finasteride BACKGROUND: Male pattern hair loss (MPHL) is a potentially reversible condition in which dihydrotestosterone is an important etiologic factor. OBJECTIVE: Our aim was to evaluate the efficacy of the type 1 and 2 5alpha-reductase inhibitor dutasteride in men with MPHL. METHODS: Four hundred sixteen men, 21 to 45 years old, were randomized to receive dutasteride 0.05, 0.1, 0.5 or 2.5 mg, finasteride 5 mg, or placebo daily for 24 weeks. RESULTS: Dutasteride increased target area hair count versus placebo in a dose-dependent fashion and dutasteride 2.5 mg was superior to finasteride at 12 and 24 weeks. Expert panel photographic review and investigator assessment of hair growth confirmed these results. Scalp and serum dihydrotestosterone levels decreased, and testosterone levels increased, in a dose-dependent fashion with dutasteride. LIMITATIONS: The study was limited to 24 weeks. CONCLUSION: Dutasteride increases scalp hair growth in men with MPHL. Type 1 and type 2 5alpha-reductase may be important in the pathogenesis and treatment of MPHL. HairSite Admin is located in [NA] and he is available to meet: NO --- I offer research assistance for HairSite. email: hairsite@aol.com for free consultations ===================================== reminder: 1. Help China Earthquake Victims 2. Free hair replacement system for men & women
brm his room, 11.05.2008, 23:10 @ HairSite Admin	Dutasteride versus finasteride Post reply
	Total testosterone may not be the real stake. rather free T. And they say nothing about this. brm is located in HIS ROOM and he is available to meet: YES email hairsite@aol.com to arrange a meeting.