col
27.04.2009, 10:23 |
ADERANS RESEARCH Launches Second Phase of Hair Loss Study - 27 Apr 2009 (Hair Loss Research & Clinical Trials) |
ADERANS RESEARCH Launches Second Phase of Hair Loss Study
http://www.prweb.com/releases/pattern_hair_loss_study/hair_restoration_research/prweb2358404.htm
27 Apr 2009
Aderans Research Institute Inc. (ARI) announced today it has launched Phase 2 of its clinical study on cell-based hair regeneration for men and women. Structured around the findings of the recently completed Phase 1 of the study, this second phase will continue to evaluate the impact of its novel cell treatment process on pattern hair loss, also known as androgenetic alopecia.
Phase 2 of the study is being conducted in six U.S. cities: Atlanta, Boston, New York, Raleigh, Houston, and Washington DC. Phase 1 was conducted exclusively in the United Kingdom.
"The second phase of this study is another step in our efforts to truly understand the impact of regenerative cell therapy on pattern hair loss. It's a tremendous opportunity," says Kurt Stenn, MD, Vice President and Chief Scientific Officer. The company's research is focused on developing a state-of-the-art tissue engineering solution to the regeneration of hair, taking actual hair cells--fibroblasts and keratinocytes, the two primary cell types within hair follicles--and promoting their growth in controlled laboratory environments. The research teams then recombine them and these "combined hair cells" are then placed in the patient's skin, where they are expected to elicit hair growth. "This is research the industry has always wanted to do, and ARI has combined the support, the market, and the scientific wherewithal to do it," says Vern Liebmann, Vice President, Operations.
More information on study outcomes will be released as our studies conclude. To see ARI's latest clinical updates, please visit
http://www.aderansresearch.com/ari_clinicupdates.html
With offices in Atlanta and Philadelphia, the Aderans Research Institute is a subsidiary of Aderans Company, Ltd, the world's largest wig manufacturer, and an affiliate of Bosley, a global leader in medical hair restoration.
Additional information on ARI can be found at http://www.aderansresearch.com
col is located in [NA] and he is available to meet: NO |
benji
27.04.2009, 12:35
@ col
|
ADERANS RESEARCH Launches Second Phase of Hair Loss Study - 27 Apr 2009 |
great news, thanks col
lets all keep our fingers crossed for a successful trial, aderans has been at it for years......
benji is located in [NA] and he is available to meet: NO |
fckhrls
27.04.2009, 15:00
@ benji
|
ADERANS RESEARCH Launches Second Phase of Hair Loss Study - 27 Apr 2009 |
» great news, thanks col
»
» lets all keep our fingers crossed for a successful trial, aderans has been
» at it for years......
Even if it fails, there seems to be a number of exciting things going on in the field. I really do think we'll see a much more effective therapy within the next 10 years or so.
fckhrls is located in [NA] and he is available to meet: NO |
Sceptic
27.04.2009, 15:20
@ fckhrls
|
ADERANS RESEARCH Launches Second Phase of Hair Loss Study - 27 Apr 2009 |
» ... within the next 10 years or so ...
OMG, do you want Baldlatino to suffer a heart attack ? It's 10 months !!
Sceptic is located in [NA] and he is available to meet: NO |
Spanish Dude
27.04.2009, 15:25
@ Sceptic
|
ADERANS RESEARCH Launches Second Phase of Hair Loss Study - 27 Apr 2009 |
» » ... within the next 10 years or so ...
»
» OMG, do you want Baldlatino to suffer a heart attack ? It's 10 months !!
LOOOL. Well, if it is 10 years, I am also going to have a hart attack.
Spanish Dude is located in [NA] and he is available to meet: NO |
Spanish Dude
27.04.2009, 15:28
@ col
|
ADERANS RESEARCH Launches Second Phase of Hair Loss Study - 27 Apr 2009 |
Ok, nothing about the specifics of the trial:
-Number of trialists.
-Use of scaffolds or not.
-Duration of the trial.
We will see...
They are being quite silent about it. this means that they are not using these trials for propaganda purposes, which is a good sign.
» ADERANS RESEARCH Launches Second Phase of Hair Loss Study
» http://www.prweb.com/releases/pattern_hair_loss_study/hair_restoration_research/prweb2358404.htm
» 27 Apr 2009
»
» Aderans Research Institute Inc. (ARI) announced today it has launched
» Phase 2 of its clinical study on cell-based hair regeneration for men and
» women. Structured around the findings of the recently completed Phase 1 of
» the study, this second phase will continue to evaluate the impact of its
» novel cell treatment process on pattern hair loss, also known as
» androgenetic alopecia.
»
» Phase 2 of the study is being conducted in six U.S. cities: Atlanta,
» Boston, New York, Raleigh, Houston, and Washington DC. Phase 1 was
» conducted exclusively in the United Kingdom.
»
» "The second phase of this study is another step in our efforts to truly
» understand the impact of regenerative cell therapy on pattern hair loss.
» It's a tremendous opportunity," says Kurt Stenn, MD, Vice President and
» Chief Scientific Officer. The company's research is focused on developing a
» state-of-the-art tissue engineering solution to the regeneration of hair,
» taking actual hair cells--fibroblasts and keratinocytes, the two primary
» cell types within hair follicles--and promoting their growth in controlled
» laboratory environments. The research teams then recombine them and these
» "combined hair cells" are then placed in the patient's skin, where they are
» expected to elicit hair growth. "This is research the industry has always
» wanted to do, and ARI has combined the support, the market, and the
» scientific wherewithal to do it," says Vern Liebmann, Vice President,
» Operations.
»
» More information on study outcomes will be released as our studies
» conclude. To see ARI's latest clinical updates, please visit
» http://www.aderansresearch.com/ari_clinicupdates.html
»
» With offices in Atlanta and Philadelphia, the Aderans Research Institute
» is a subsidiary of Aderans Company, Ltd, the world's largest wig
» manufacturer, and an affiliate of Bosley, a global leader in medical hair
» restoration.
»
» Additional information on ARI can be found at
» http://www.aderansresearch.com
Spanish Dude is located in [NA] and he is available to meet: NO |
fckhrls
27.04.2009, 15:31
@ Sceptic
|
ADERANS RESEARCH Launches Second Phase of Hair Loss Study - 27 Apr 2009 |
» » ... within the next 10 years or so ...
»
» OMG, do you want Baldlatino to suffer a heart attack ? It's 10 months !!
LOL
I'm assuming Aderans fails. If it works, then it would be inside 5 year.
Either way, I think the field is zeroing in on the problem. The more they fail, the closer they get.
fckhrls is located in [NA] and he is available to meet: NO |
debris
27.04.2009, 15:32
@ col
|
Finally something that could finish trials in 5 years (if everything goes well) |
And if it actually works.
debris has 1 Personal Journal(s). Click here to view
debris is located in [NA] and he is available to meet: NO |
MuscleBoy2
27.04.2009, 17:00
@ debris
|
Finally something that could finish trials in 5 years (if everything goes well) |
I think we will have some sort of advancement in the HM field with the use of stem cells pretty soon. A lot of doctors and scientists are studying this and know that it works-- it's just a matter of perfecting it. In the end, I don't think HT doctors would lose business because of this because I'm sure it's still going to involve carefully creating hairlines and such? All in all, I'm optimistic about what the future holds 
MuscleBoy2 is located in [NA] and he is available to meet: NO |
fckhrls
27.04.2009, 17:14
@ MuscleBoy2
|
Finally something that could finish trials in 5 years (if everything goes well) |
» In the end, I don't think HT doctors would lose business because of this because
» I'm sure it's still going to involve carefully creating hairlines and such?
» All in all, I'm optimistic about what the future holds
The conspiracy theories make no sense. HM will increase the volume of patients, while its cost will increase their gross revenues. Very few are willing to have HTs because the results generally suck and its fairly invasive. If a proceadure was developed that produced excellent results with minimal pain and downtime, many, many more people would be willing to have it done. The fact that Bosely is involved underscores this market reality; they see potential, not drawbacks.
fckhrls is located in [NA] and he is available to meet: NO |
MuscleBoy2
27.04.2009, 17:46
@ fckhrls
|
Finally something that could finish trials in 5 years (if everything goes well) |
I agree with you.. Bosley going after HM is a sign that something's still in it for them
MuscleBoy2 is located in [NA] and he is available to meet: NO |
cal
27.04.2009, 17:51
@ MuscleBoy2
|
Finally something that could finish trials in 5 years (if everything goes well) |
The horse industry didn't keep the automobile off the market.
The VCR/VHS tape cartel didn't keep DVDs out of our hands.
The HT industry will not pose any major roadblock for HM.
cal is located in [NA] and he is available to meet: NO |
MuscleBoy2
27.04.2009, 19:54
@ cal
|
Finally something that could finish trials in 5 years (if everything goes well) |
By the way, it's great to see ARI is finally moving forward. Seven years ago they saw a lot of promise in the field. I haven't followed them enough to know what hurdles they faced during those seven years, but it's great to see that they're finally starting phase 2.
MuscleBoy2 is located in [NA] and he is available to meet: NO |
cal
27.04.2009, 20:14
@ MuscleBoy2
|
Finally something that could finish trials in 5 years (if everything goes well) |
They've been quiet because they just haven't really needed anything from the public (or investors) for several years. They've had no incentive to make news.
They might actually be making quite a lot of progress for all we know. Their basic plan seems like a more elaborate version of the ICX-TRC program that also probably has a better shot at working well.
cal is located in [NA] and he is available to meet: NO |
sphlanx2006
27.04.2009, 22:10
@ cal
|
Finally something that could finish trials in 5 years (if everything goes well) |
Since aderans and ICX are related (Bosley and others) i believe that aderans has also information on the TRC protocol. The timing of their trials looks like they waited for TRC to conclude. If that is the case i guess they have much more chances to create something that works.
sphlanx2006 is located in [NA] and he is available to meet: NO |
pauly
27.04.2009, 22:45
@ col
|
phase 1 results???? |
no details on phase 1 results?
pauly is located in [NA] and he is available to meet: NO |
Max
28.04.2009, 05:52
@ pauly
|
phase 1 results???? |
Can somone conact the Compeny and ask,when they want to go on the marked?
Max is located in [NA] and he is available to meet: NO |
Spanish Dude
28.04.2009, 07:48
@ pauly
|
phase 1 results???? |
» no details on phase 1 results?
I have the same question. They must be satisfactory, otherwise they would not launch a multicenter phase II trial with 100 trialists (number to be confirmed).
Again, the secrecy of these trials is a good sign. They are not being used as propaganda.
Spanish Dude is located in [NA] and he is available to meet: NO |
goata007
28.04.2009, 11:51
@ Max
|
phase 1 results???? |
» Can somone conact the Compeny and ask,when they want to go on the marked?
I remember someone quoted Washnik saying "end of this decade". If FDA allows them to launch their product after phase-II then they could do it by the end of 2010 or start of 2011.
goata007 is located in [NA] and he is available to meet: NO ---
"If we knew what it was that we were doing, it wouldn't be called research, would it?" - Albert Einstein |
Max
28.04.2009, 12:14
@ goata007
|
phase 1 results???? |
» » Can somone conact the Compeny and ask,when they want to go on the
» marked?
»
» I remember someone quoted Washnik saying "end of this decade". If FDA
» allows them to launch their product after phase-II then they could do it by
» the end of 2010 or start of 2011.
Thiiiiiisssssssssss Chhhhhhhhhhhhhhhhriiiiiiiiiiiiiismmmmmmmmmmmasssssssssss,i
gave you your hhhhhaaaaaaaaaaaaaair,and the very next dayyyyyyyyyy,you are back in liiiiiiiiiiiiiiiiiiveeeeeeeeeeeeee
Max is located in [NA] and he is available to meet: NO |
topcat611
28.04.2009, 13:58
@ goata007
|
phase 1 results???? |
» » Can somone conact the Compeny and ask,when they want to go on the
» marked?
»
» I remember someone quoted Washnik saying "end of this decade". If FDA
» allows them to launch their product after phase-II then they could do it by
» the end of 2010 or start of 2011.
If it is just entering phase 2, then approval is about 5-7 years away if everything goes well. Biotech companies in general have to be careful what they say, and the amount of informaiton they release. Too much, and they are at a high risk for lawsuits from investors. Reputable companies don't pump.
The FDA does not allow approval after phase 2. It is only when people are dying and a treatment shows efficacy very early on that the process has a chance for a quicker review or a limited use.
Even if the process is approved it can be removed from the market at a later date if safety becomes a problem. So you don't necessarily want to be the first one in the water.
topcat611 has 1 Personal Journal(s). Click here to view
topcat611 is located in [NA] and he is available to meet: NO ---
I recently won a pro bono offer for repair work with BHR. I will keep everyone updated on my progess after the procedure.
I am not a HT doctor, I am a HT victim.
http://hairsite.com/serendipity/authors/19-Topcat611
http://hairtransplantrepair.blogspot.com/ |
ixan
28.04.2009, 14:16
@ col
|
money talks |
Aderans is a large organization, if you have money you can make things happen more easily.
ixan is located in [NA] and he is available to meet: NO |
goata007
28.04.2009, 14:23
@ topcat611
|
phase 1 results???? |
» If it is just entering phase 2, then approval is about 5-7 years away if
» everything goes well. Biotech companies in general have to be careful what
» they say, and the amount of informaiton they release. Too much, and they
» are at a high risk for lawsuits from investors. Reputable companies don't
» pump.
I just mentioned what washnik's statement, what's their latest estimate - I have no idea.
» The FDA does not allow approval after phase 2. It is only when people are
» dying and a treatment shows efficacy very early on that the process
» has a chance for a quicker review or a limited use.
I'm not really sure if FDA is regulating this or not, so I really won't comment on this matter.
goata007 is located in [NA] and he is available to meet: NO ---
"If we knew what it was that we were doing, it wouldn't be called research, would it?" - Albert Einstein |
mjones
28.04.2009, 14:48
@ goata007
|
phase 1 results???? |
» » If it is just entering phase 2, then approval is about 5-7 years away if
» » everything goes well. Biotech companies in general have to be careful
» what
» » they say, and the amount of informaiton they release. Too much, and
» they
» » are at a high risk for lawsuits from investors. Reputable companies
» don't
» » pump.
»
» I just mentioned what washnik's statement, what's their latest estimate -
» I have no idea.
»
» » The FDA does not allow approval after phase 2. It is only when people
» are
» » dying and a treatment shows efficacy very early on that the
» process
» » has a chance for a quicker review or a limited use.
»
» I'm not really sure if FDA is regulating this or not, so I really won't
» comment on this matter.
HAHHAHAHAHHAHHHHAHAAHAH...SAME CRAP!!!! I will be happy when i see someone walking out of a Bosley Clinic with all his hair back..until then 5yr 10 yrs 1000 yrs dinosaurs come back..whatever..lol
mjones is located in [NA] and he is available to meet: NO |
fckhrls
28.04.2009, 19:15
@ topcat611
|
phase 1 results???? |
» » » Can somone conact the Compeny and ask,when they want to go on the
» » marked?
» »
» » I remember someone quoted Washnik saying "end of this decade". If FDA
» » allows them to launch their product after phase-II then they could do it
» by
» » the end of 2010 or start of 2011.
»
» If it is just entering phase 2, then approval is about 5-7 years away if
» everything goes well. Biotech companies in general have to be careful what
» they say, and the amount of informaiton they release. Too much, and they
» are at a high risk for lawsuits from investors. Reputable companies don't
» pump.
»
» The FDA does not allow approval after phase 2. It is only when people are
» dying and a treatment shows efficacy very early on that the process
» has a chance for a quicker review or a limited use.
»
» Even if the process is approved it can be removed from the market at a
» later date if safety becomes a problem. So you don't necessarily want to be
» the first one in the water.
The average length of trials (1 through 3) is 8 years, so I don't think it will take 7 years to get to market. Of course, that's IF it works, which is a huge "if". I'd say 5 years to market if it actually works. If they've just started recruiting cohorts for Phase II, there is NO way its getting to market before 2012.
fckhrls is located in [NA] and he is available to meet: NO |
damraak
28.04.2009, 19:37
@ fckhrls
|
how many years to complete phase 1 |
» The average length of trials (1 through 3) is 8 years, so I don't think it
» will take 7 years to get to market. Of course, that's IF it works, which
» is a huge "if". I'd say 5 years to market if it actually works. If
» they've just started recruiting cohorts for Phase II, there is NO way its
» getting to market before 2012.
Does anyone know how many years it took them to complete phase 1? This will give us an idea how fast they are moving with this.
damraak is located in [NA] and he is available to meet: NO |
MuscleBoy2
28.04.2009, 22:09
@ damraak
|
how many years to complete phase 1 |
» Does anyone know how many years it took them to complete phase 1? This
» will give us an idea how fast they are moving with this.
I do know they were in their research phase at the end of 2002. Not sure when Phase 1 officially began. I'm also not sure what hurdles they may have faced during those 6-7 years. The fact they're moving onto phase 2 though is a good thing. I read somewhere that they would be finished with phase 2 by the end of this year. So if all goes well, phase 3 could start next year I'm assuming.
MuscleBoy2 is located in [NA] and he is available to meet: NO |
Slime707
29.04.2009, 00:00
@ MuscleBoy2
|
how many years to complete phase 1 |
Didn't Aderans conduct their phase I trials in the UK? Does that not mean they weren't going through the FDA at that point? Sure, the procedure (if it works) will require FDA approval to be made available in the US, but it's a possibility we could see something in another country before then.
Slime707 is located in [NA] and he is available to meet: NO |
debris
29.04.2009, 03:03
@ damraak
|
how many years to complete phase 1 |
» » The average length of trials (1 through 3) is 8 years, so I don't think
» it
» » will take 7 years to get to market. Of course, that's IF it works,
» which
» » is a huge "if". I'd say 5 years to market if it actually works. If
» » they've just started recruiting cohorts for Phase II, there is NO way
» its
» » getting to market before 2012.
»
» Does anyone know how many years it took them to complete phase 1? This
» will give us an idea how fast they are moving with this.
I think there were talks about aderans being in phase I two or three years ago.
debris has 1 Personal Journal(s). Click here to view
debris is located in [NA] and he is available to meet: NO |
cal
29.04.2009, 03:45
@ debris
|
how many years to complete phase 1 |
Well, regardless of when & where & all that, it's probably the phase#2 that matters most.
Phase#1 just proves it won't hurt anyone. Phase#3 is mostly the finer-tuning of the effectiveness. It's phase#2 that most directly proves the whole stupid procedure is capable of working.
If they finish phase#2 and announce it worked well enough to proceed with phase#3, THEN I'll start getting excited about this really happening soon.
cal is located in [NA] and he is available to meet: NO |
pauly
29.04.2009, 10:20
@ damraak
|
since 2004, 5 years |
i hve been coming here for about 5 years now, i remember it was about 2004 when aderans first talked about doing their trials, so it took 5 years to finish phase 1 ? is that possible? 5 friggn years for phase 1?
pauly is located in [NA] and he is available to meet: NO |
topcat611
29.04.2009, 13:34
@ pauly
|
since 2004, 5 years |
» i hve been coming here for about 5 years now, i remember it was about 2004
» when aderans first talked about doing their trials, so it took 5 years to
» finish phase 1 ? is that possible? 5 friggn years for phase 1?
The probably didn't have a set protocol to test.
Overall it takes 10 years. You have the actual trials and the time in between to raise funds. Usually after a successful phase 2 most companies will partner with an even larger company with deeper pockets in order to spread the risk. If a company is really greedy they will attempt to fund a phase 3 on their own. If they fail, which is more apt to happen without that bigger partner, they go out of business and the technology is sold off.
You see the system is corrupt. I know it's hard to believe that big business and government are corrupt. But without that bigger partner that has the FDA connections, approval is extremely difficult. Especially if you are stepping on too many toes.
At this point, it truly is at least 5 years away.
topcat611 has 1 Personal Journal(s). Click here to view
topcat611 is located in [NA] and he is available to meet: NO ---
I recently won a pro bono offer for repair work with BHR. I will keep everyone updated on my progess after the procedure.
I am not a HT doctor, I am a HT victim.
http://hairsite.com/serendipity/authors/19-Topcat611
http://hairtransplantrepair.blogspot.com/ |
James Bond
02.05.2009, 20:19
@ col
|
ADERANS RESEARCH Launches Second Phase of Hair Loss Study - 27 Apr 2009 |
Due to technical issues with HM consistency, ARI's technique has a far greater chance of success than Gho's or ICX'. Gho was the early pioneer and actually used CD34+ stem cells from the patient's blood to fortify the nutrient mix and enhance the hair follicle stem cells ability to multiply and remain viable. But despite his brilliant pioneering idea, he could never develop a consistent protocol.
Gho had done some early research into ICX' technique and abandoned it in favor of using hair follicle stem cells mixed with blood stem cell aggregates and kerotinocyte growth factors. Thus, unless ICX could figure out some new way to culture viable DP cells in 2-D suspensions, their research was bound to come up against (and did) similar consistency issues as Gho encountered.
ARI has spent a great deal of time in the lab studying these issues and outcomes, and they're very familiar with the problems other researchers have encountered. Their emphasis is on 3-D environments using a multi-cell approach. IOW, they specialize in creating a self-contained environment that relies less on the patient's existing cells interacting with the injected cells. What separates this from previous companies' trials is this has never been tried before in humans. So it should prove to be quite exciting.
ARI's approach is not a backyard approach. Kurt Stenn is a world-class hair follicle researcher and has assembled a team of researchers with impeccable credentials. ARI has taken its time in the lab (mostly because the issues are so difficult to solve), but I see this a good thing. The earlier attempts by other companies have been thwarted more than anything by lack of developing a consistent protocol prior to moving into human research. ARI's approach is different on many different levels and stands a high chance of commercial success. The amount of time and experiments they performed in the lab leading up to human trials is unprecedented. In many ways, this is the real deal this time. However, despite this, I expect the product will be clunky when it's first released (if it makes it that far).
Phase II trials are typically 20-300 people, so ARI's effort can be thought of as a legitimate mid-level attempt (quite expensive). If they have success, most likely the phase III trials will be quite a bit bigger than phase II. Phase III trials typically involve 300-3000 people and cost an arm and a leg. So if we see a failure, it will most likely play out in phase II with a reluctance to continue funding.
Technically ARI could finishes phase II in a year, enter and finish phase III in another year, and then submit the product for FDA review and get it on the shelf. However, that is not likely to happen. 2.5 years is possible, but "5 years" is more likely. LOL
James Bond is located in [NA] and he is available to meet: NO |
fckhrls
02.05.2009, 20:59
@ James Bond
|
ADERANS RESEARCH Launches Second Phase of Hair Loss Study - 27 Apr 2009 |
» Due to technical issues with HM consistency, ARI's technique has a far
» greater chance of success than Gho's or ICX'. Gho was the early pioneer and
» actually used CD34+ stem cells from the patient's blood to fortify the
» nutrient mix and enhance the hair follicle stem cells ability to multiply
» and remain viable. But despite his brilliant pioneering idea, he could
» never develop a consistent protocol.
»
» Gho had done some early research into ICX' technique and abandoned it in
» favor of using hair follicle stem cells mixed with blood stem cell
» aggregates and kerotinocyte growth factors. Thus, unless ICX could figure
» out some new way to culture viable DP cells in 2-D suspensions, their
» research was bound to come up against (and did) similar consistency issues
» as Gho encountered.
»
» ARI has spent a great deal of time in the lab studying these issues and
» outcomes, and they're very familiar with the problems other researchers
» have encountered. Their emphasis is on 3-D environments using a multi-cell
» approach. IOW, they specialize in creating a self-contained environment
» that relies less on the patient's existing cells interacting with the
» injected cells. What separates this from previous companies' trials is this
» has never been tried before in humans. So it should prove to be quite
» exciting.
»
» ARI's approach is not a backyard approach. Kurt Stenn is a world-class
» hair follicle researcher and has assembled a team of researchers with
» impeccable credentials. ARI has taken its time in the lab (mostly because
» the issues are so difficult to solve), but I see this a good thing. The
» earlier attempts by other companies have been thwarted more than anything
» by lack of developing a consistent protocol prior to moving into human
» research. ARI's approach is different on many different levels and stands a
» high chance of commercial success. The amount of time and experiments they
» performed in the lab leading up to human trials is unprecedented. In many
» ways, this is the real deal this time. However, despite this, I expect the
» product will be clunky when it's first released (if it makes it that far).
»
» Phase II trials are typically 20-300 people, so ARI's effort can be
» thought of as a legitimate mid-level attempt (quite expensive). If they
» have success, most likely the phase III trials will be quite a bit bigger
» than phase II. Phase III trials typically involve 300-3000 people and cost
» an arm and a leg. So if we see a failure, it will most likely play out in
» phase II with a reluctance to continue funding.
»
» Technically ARI could finishes phase II in a year, enter and finish phase
» III in another year, and then submit the product for FDA review and get it
» on the shelf. However, that is not likely to happen. 2.5 years is possible,
» but "5 years" is more likely. LOL
Excellent post. Win, lose or draw, ARI's research should be very useful for future study.
fckhrls is located in [NA] and he is available to meet: NO |
MuscleBoy2
03.05.2009, 10:31
@ fckhrls
|
ADERANS RESEARCH Launches Second Phase of Hair Loss Study - 27 Apr 2009 |
I agree with you James. ARI did state that funding was not an issue. Hopefully things will go well this year and they will move onto phase 3 in a year or so.
MuscleBoy2 is located in [NA] and he is available to meet: NO |
chipper
08.05.2009, 04:50
@ col
|
ADERANS RESEARCH Launches Second Phase of Hair Loss Study - 27 Apr 2009 |
» ADERANS RESEARCH Launches Second Phase of Hair Loss Study
» http://www.prweb.com/releases/pattern_hair_loss_study/hair_restoration_research/prweb2358404.htm
» 27 Apr 2009
»
» Aderans Research Institute Inc. (ARI) announced today it has launched
» Phase 2 of its clinical study on cell-based hair regeneration for men and
» women. Structured around the findings of the recently completed Phase 1 of
» the study, this second phase will continue to evaluate the impact of its
» novel cell treatment process on pattern hair loss, also known as
» androgenetic alopecia.
»
» Phase 2 of the study is being conducted in six U.S. cities: Atlanta,
» Boston, New York, Raleigh, Houston, and Washington DC. Phase 1 was
» conducted exclusively in the United Kingdom.
»
» "The second phase of this study is another step in our efforts to truly
» understand the impact of regenerative cell therapy on pattern hair loss.
» It's a tremendous opportunity," says Kurt Stenn, MD, Vice President and
» Chief Scientific Officer. The company's research is focused on developing a
» state-of-the-art tissue engineering solution to the regeneration of hair,
» taking actual hair cells--fibroblasts and keratinocytes, the two primary
» cell types within hair follicles--and promoting their growth in controlled
» laboratory environments. The research teams then recombine them and these
» "combined hair cells" are then placed in the patient's skin, where they are
» expected to elicit hair growth. "This is research the industry has always
» wanted to do, and ARI has combined the support, the market, and the
» scientific wherewithal to do it," says Vern Liebmann, Vice President,
» Operations.
»
» More information on study outcomes will be released as our studies
» conclude. To see ARI's latest clinical updates, please visit
» http://www.aderansresearch.com/ari_clinicupdates.html
»
» With offices in Atlanta and Philadelphia, the Aderans Research Institute
» is a subsidiary of Aderans Company, Ltd, the world's largest wig
» manufacturer, and an affiliate of Bosley, a global leader in medical hair
» restoration.
»
» Additional information on ARI can be found at
» http://www.aderansresearch.com
big whoopdy do...it only took like 5 yrs to get past the first phase. By the time it comes out, i'll be to old enough to give a crap anymore. I'm betting the results won't be what we expect either.
chipper is located in [NA] and he is available to meet: NO |
BALDIE-IS-BACK-GO
08.05.2009, 05:28
@ chipper
|
ADERANS RESEARCH Launches Second Phase of Hair Loss Study - 27 Apr 2009 |
» » ADERANS RESEARCH Launches Second Phase of Hair Loss Study
» »
» http://www.prweb.com/releases/pattern_hair_loss_study/hair_restoration_research/prweb2358404.htm
» » 27 Apr 2009
» »
» » Aderans Research Institute Inc. (ARI) announced today it has launched
» » Phase 2 of its clinical study on cell-based hair regeneration for men
» and
» » women. Structured around the findings of the recently completed Phase 1
» of
» » the study, this second phase will continue to evaluate the impact of
» its
» » novel cell treatment process on pattern hair loss, also known as
» » androgenetic alopecia.
» »
» » Phase 2 of the study is being conducted in six U.S. cities: Atlanta,
» » Boston, New York, Raleigh, Houston, and Washington DC. Phase 1 was
» » conducted exclusively in the United Kingdom.
» »
» » "The second phase of this study is another step in our efforts to truly
» » understand the impact of regenerative cell therapy on pattern hair
» loss.
» » It's a tremendous opportunity," says Kurt Stenn, MD, Vice President and
» » Chief Scientific Officer. The company's research is focused on
» developing a
» » state-of-the-art tissue engineering solution to the regeneration of
» hair,
» » taking actual hair cells--fibroblasts and keratinocytes, the two
» primary
» » cell types within hair follicles--and promoting their growth in
» controlled
» » laboratory environments. The research teams then recombine them and
» these
» » "combined hair cells" are then placed in the patient's skin, where they
» are
» » expected to elicit hair growth. "This is research the industry has
» always
» » wanted to do, and ARI has combined the support, the market, and the
» » scientific wherewithal to do it," says Vern Liebmann, Vice President,
» » Operations.
» »
» » More information on study outcomes will be released as our studies
» » conclude. To see ARI's latest clinical updates, please visit
» » http://www.aderansresearch.com/ari_clinicupdates.html
» »
» » With offices in Atlanta and Philadelphia, the Aderans Research
» Institute
» » is a subsidiary of Aderans Company, Ltd, the world's largest wig
» » manufacturer, and an affiliate of Bosley, a global leader in medical
» hair
» » restoration.
» »
» » Additional information on ARI can be found at
» » http://www.aderansresearch.com
»
»
» big whoopdy do...it only took like 5 yrs to get past the first phase. By
» the time it comes out, i'll be to old enough to give a crap anymore. I'm
» betting the results won't be what we expect either.
If you do not like your hairloss,when your younger,I'm guessing that feeling never goes away whatever age.It might become more acceptable,as you age,as others around are getting balder,as well!
I'm now 44.I hate my hairloss.Luckily I never took much notice until a couple of years ago,or not so lucky which ever way you look at it.
I just hate having to shave my damn head every day - I think the totally shaved look is better than thinning hair.I really wish I could just get over it.
BALDIE-IS-BACK-GO is located in [NA] and he is available to meet: NO |
gladietor20
08.05.2009, 17:32
@ col
|
ADERANS RESEARCH Launches Second Phase of Hair Loss Study - 27 Apr 2009 |
[color=red][/color]how many times you write this old article as a new
announcement!!!!!!!!!!!!!????????????????????
gladietor20 is located in [NA] and he is available to meet: NO |
Max
18.05.2009, 10:47
@ gladietor20
|
When is this trail finished |
And can we get the results after that?
Max is located in [NA] and he is available to meet: NO |
MuscleBoy2
25.05.2009, 10:47
@ Max
|
When is this trail finished |
Should take about a year to finish phase 2 of the trials.
MuscleBoy2 is located in [NA] and he is available to meet: NO |
thegreek
25.05.2009, 11:11
@ MuscleBoy2
|
phase 3 means they did it |
» Should take about a year to finish phase 2 of the trials.
Well phase 2 is the most important part. It will prove how well it works, noone should get excited now, we have seen these phase 1 and 2 trials all the time.I remember even tricomin finished phase 2 and that was it, it wasn't that good for investors to through in money for a phase 3 trial. So they skipped phase 3 and started selling it, but i am sure noone has more hair from tricomin than propecia or rogaine. Phase 3 separates the "i think i see a new hair on my temple that wasnt there before" from "propecia slowed my hairloss, i have rogrowth on the crown and my hair look so healthy and alive again"
The main point is if you see something going into phase 3, then there is 99% chance we have a REAL WORKING SOLUTION, a solution that is expected to bring profit to the investors.
All these phase 1 and phase 2 are relatively cheap trials to perform so its not such big news that these companies do them. They are hoping that the results are so good that the product will sell. And if it isn't... well at least they tried, its not as if they lost millions. Dont get excited just because they go to phase 2, no-one stops at phase 1 unless there are serious side-effects
ICX-trc didn't impress anyone,so the phase 3 is highly unlikely... why Aderans should be different?...i honestly dont know... but for sure they are gonna try to see if they get it better than ICX, why not? they have the funding ready they have to at least try it. but just because they are trying it doesn't mean they gonna do it....
keep a very very small basket... many tried before and didn't do it, Aderans is a long shot as well...a shot that they have to take anyhow since all these years money was poured into this effort all because the hype was great with stem cells and many people wanted to invest there so these companies took off and gathered all the necessary money for... taking long shots. But the money needed for phase 3 is a whole new ball game, there is no long shots there... investors will want to see if the long shot did it to invest many more so that they can get back even more...so if they get that money we will all have far more donor than before
thegreek has 1 Personal Journal(s). Click here to view
thegreek is located in [NA] and he is available to meet: NO |
MuscleBoy2
25.05.2009, 22:13
@ thegreek
|
phase 3 means they did it |
Keep in mind, Aderans is affiliated with Bosley and Aderans has claimed that funding is not an issue. Hopefully we'll see successful results with phase 2.
MuscleBoy2 is located in [NA] and he is available to meet: NO |
thegreek
26.05.2009, 08:26
@ MuscleBoy2
|
phase 3 means they did it |
» Keep in mind, Aderans is affiliated with Bosley and Aderans has claimed
» that funding is not an issue. Hopefully we'll see successful results with
» phase 2.
muscle boy it doesnt matter where funding comes from, it can be outside investors or investors that negotiated the rights of first offer like bosley did. That doesn't change anything from what i said the only difference is that Bosley-aderans have priority if they decide to invest further since its aproduct from within the company
Bosley as a business awaits for the result to decide if it is worth investing more...just like outside investors would want.
for me there are three scenarios
1. The product works very well, bosley funds the phase 3 trials and every thing is nice and good.(dream scenario )
2. the product doesn't work so well and have some minimal sideeffects, they either skip phase 3 or proceed with it and Bosley hopes that with good marketing and advertising they will promote and bring more customers to the doors. We stay here and some of us are happy others have some sides or lack of growth and complain and curse the product(bad scenario becuse they will give us hope and propably many people will loose money and still fight with hairloss)
3.The product works minimal, bosley doesn't want to invest and they try to sell the research to someone else in hope that he can do better (the worst scenario)
thegreek has 1 Personal Journal(s). Click here to view
thegreek is located in [NA] and he is available to meet: NO |
Max
26.05.2009, 08:41
@ thegreek
|
phase 3 means they did it |
Will ARI publised the results(Phase 2)
Max is located in [NA] and he is available to meet: NO |
thegreek
26.05.2009, 09:06
@ Max
|
phase 3 means they did it |
» Will ARI publised the results(Phase 2)
they will publish the results once the phase 2 finishes...we just have to wait and see.
I am very optimistic that we will see something new that will change the field of hair restoration to the better, i dont think it will be a cure but it will help hair transplants overcome their nemesis(not enough donor). there are so many companies involved. Me i wouldnt think of a transplant if you are 30 and under...something will come and its better to be a virgin scalp when it gets here.
You know what many of us hate hair transplants but if density is available and donor is not an issue we will see transplants-HM of 15000 grafts as a norm. Put some gel in hair with that much density and if someone can tell you had a transplant you can come and kick me in the butt
right now there are some kick ass resuts on people with many native hair, the main problem is how and if you can hold on to that hair and what happens if you cant hold on to them.
thegreek has 1 Personal Journal(s). Click here to view
thegreek is located in [NA] and he is available to meet: NO |
MuscleBoy2
26.05.2009, 16:40
@ thegreek
|
phase 3 means they did it |
TheGreek, I agree that we will most likely have something to help restore hair in combination with traditional hair transplants pretty soon. Whatever comes out will take away the issue of insufficient donor hair. Might it produce 100,000 hairs? I don't know. Will the hair fall out in another 18-25 years after it begins to feel the impacts of DHT? Who knows? But it would provide an infinite number of hairs that would not have been possible with traditional transplants. And even if the hairs become susceptible to DHT in 18 years, you can still create more hair at that point.
Going back to Aderans, the company has spent over 5 years researching hair regeneration. Their phase 1 was very extensive and they tried to get the best possible experimental product before starting up. They had all the thinking laid out over 5 years ago, but are just starting phase 2 this year. This to me says that they obviously had hurdles to overcome, but that they also did a lot of extensive research, perhaps more than any other company has up until this point. This doesn't guarantee success in phase 2, but it at least raises the potential for success.
MuscleBoy2 is located in [NA] and he is available to meet: NO |
krapok
24.07.2009, 05:53
@ col
|
ADERANS RESEARCH Launches Second Phase of Hair Loss Study - 27 Apr 2009 |
Seems that these guys has troubles cloning hair and they don't bring nothing to the market any recent years.
I read their website fully several times and there were written before:
“We anticipate that patients will have access to hair multiplication technology by the end of the decade, and will enjoy the convenience of same-day office visits, much like the most common cosmetic procedures.”
And now i checked their website again and they have changed this sentence:
We anticipate that patients will in coming years have access to hair regeneration technology, and will enjoy the convenience of same-day office visits, much like the most common cosmetic procedures.
This can mean only that they don't have any ideas exactly when hair cloning can became available. They have delayed several times before (the last time when they promised to bring HM on the market was 2007?) and seems they are doing this again. "In coming years" can mean 10, 20, 50, ... years.
What do you think guys?
krapok is located in [NA] and he is available to meet: NO |
FightingFalcon
24.07.2009, 11:36
@ krapok
|
ADERANS RESEARCH Launches Second Phase of Hair Loss Study - 27 Apr 2009 |
» I read their website fully several times and there were written before:
» “We anticipate that patients will have access to hair multiplication
» technology by the end of the decade, and will enjoy the
» convenience of same-day office visits, much like the most common cosmetic
» procedures.”
»
» And now i checked their website again and they have changed this
» sentence:
» We anticipate that patients will in coming years
» have access to hair regeneration technology, and will enjoy the convenience
» of same-day office visits, much like the most common cosmetic
» procedures.
»
» This can mean only that they don't have any ideas exactly when hair
» cloning can became available. They have delayed several times before (the
» last time when they promised to bring HM on the market was 2007?) and seems
» they are doing this again. "In coming years" can mean 10, 20, 50, ...
» years.
»
» What do you think guys?
Obviously if they are finishing up phase II in a few months (around the end of this year) then they're not going to market by the end of the decade. If phase II finishes on time, with one more phase to go that means they'll have something out in about 4 years. Unless Aderans runs out of money (unlikely) or their technology doesn't grow ANYTHING (unlikely) they'll have something that grows some hair out by then.
So far, progress on their clinical trials has been good, especially as compared to ICX. They got stuck a little getting the science squared away in the pre-clinical phase, and hence the delay from "by the end of the decade" to "in coming years". I think this is encouraging since it shows they wanted to get things right before going into clinical trials, unlike ICX.
FightingFalcon is located in [NA] and he is available to meet: NO |
cms
24.07.2009, 11:53
@ FightingFalcon
|
ADERANS RESEARCH Launches Second Phase of Hair Loss Study - 27 Apr 2009 |
» » I read their website fully several times and there were written before:
» » “We anticipate that patients will have access to hair multiplication
» » technology by the end of the decade, and will enjoy
» the
» » convenience of same-day office visits, much like the most common
» cosmetic
» » procedures.”
» »
» » And now i checked their website again and they have changed this
» » sentence:
» » We anticipate that patients will in coming years
» » have access to hair regeneration technology, and will enjoy the
» convenience
» » of same-day office visits, much like the most common cosmetic
» » procedures.
» »
» » This can mean only that they don't have any ideas exactly when hair
» » cloning can became available. They have delayed several times before
» (the
» » last time when they promised to bring HM on the market was 2007?) and
» seems
» » they are doing this again. "In coming years" can mean 10, 20, 50, ...
» » years.
» »
» » What do you think guys?
»
» Obviously if they are finishing up phase II in a few months (around the
» end of this year) then they're not going to market by the end of the
» decade. If phase II finishes on time, with one more phase to go that means
» they'll have something out in about 4 years. Unless Aderans runs out of
» money (unlikely) or their technology doesn't grow ANYTHING (unlikely)
» they'll have something that grows some hair out by then.
»
» So far, progress on their clinical trials has been good, especially as
» compared to ICX. They got stuck a little getting the science squared away
» in the pre-clinical phase, and hence the delay from "by the end of the
» decade" to "in coming years". I think this is encouraging since it shows
» they wanted to get things right before going into clinical trials, unlike
» ICX.
if you read the mens health article that was posted in this forum, what there are doing did NOT work on a mouse. So I dont think they got there pre trails right.
Thats what makes follica technique more impressive. Human hair on human skin. Yes it was on a mouse, but they understand that the immune system has to be suppressed. I don’t think these other companies understand this.
cms is located in [NA] and he is available to meet: NO |
cal
24.07.2009, 12:42
@ cms
|
ADERANS RESEARCH Launches Second Phase of Hair Loss Study - 27 Apr 2009 |
Lucy holds the football on the ground in kicking position. Charlie Brown believes maybe this time she won't yank it when he tries to kick it, and makes a run at it.
A company makes a prediction of getting through the FDA trials in much less than a decade. People believe it will really happen that way instead of taking the decade that it always does.
cal is located in [NA] and he is available to meet: NO |
Spanish Dude
24.07.2009, 16:36
@ krapok
|
ADERANS RESEARCH Launches Second Phase of Hair Loss Study - 27 Apr 2009 |
Thanks krapok for tracking ARI's website evolution.
Its ovious that ARI is having delays.
But in spite of this, they are launching phaseII trials. And unlike ICX crappy trials, ARI'S trial is a multicenter trial with approx 100 trialists. They must have something solid, IMO.
In the meantime, I don't have any reason to think that Follica has something solid. At least not yet. They lied about that blazing fast "proof of concept trial", and that is no good.
My hopes are on ARI now.
» Seems that these guys has troubles cloning hair and they don't bring
» nothing to the market any recent years.
»
» I read their website fully several times and there were written before:
» “We anticipate that patients will have access to hair multiplication
» technology by the end of the decade, and will enjoy the
» convenience of same-day office visits, much like the most common cosmetic
» procedures.”
»
» And now i checked their website again and they have changed this
» sentence:
» We anticipate that patients will in coming years
» have access to hair regeneration technology, and will enjoy the convenience
» of same-day office visits, much like the most common cosmetic
» procedures.
»
» This can mean only that they don't have any ideas exactly when hair
» cloning can became available. They have delayed several times before (the
» last time when they promised to bring HM on the market was 2007?) and seems
» they are doing this again. "In coming years" can mean 10, 20, 50, ...
» years.
»
» What do you think guys?
Spanish Dude is located in [NA] and he is available to meet: NO |
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