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jarjarbinx

10.02.2012, 15:43
 

It looks like 2014 is the year a hair loss cure hits the market. (Hair Multiplication & Stem Cells Treatment)

We will likely be able to fly to some other country in 2014 to get our hair back via Histogen's treatment. That will likely be the soonest it will be released outside of the US. The US will take longer because FDA takes longer than regulatory bodies in some other countries.

There is a chance that follica is doing something besides the scenes that we don't know about but I doubt it because if they were doing something it would have been in the news by now. Most likely they have ended their baldness cure ambitions. There is a chance that generic high dose bimatoprost will be on the market late this year or early 2013 but it may only be somewhat better than minoxidil rather than a huge breakthrough. Acell docs could find a way to tweak acell but I doubt it since every time I talk to an acell doctor about adding key growth factors they stop the line of communication.

I think we are most likely looking at 2014 for a baldness cure unless we catch a break from somewhere.




jarjarbinx is located in [NA] and he is available to meet: NO


Post reply
2020

10.02.2012, 21:34

@ jarjarbinx

It looks like 2014 is the year a hair loss cure hits the market.

» We will likely be able to fly to some other country in 2014 to get our hair
» back via Histogen's treatment. That will likely be the soonest it will be
» released outside of the US. The US will take longer because FDA takes
» longer than regulatory bodies in some other countries.
»
» There is a chance that follica is doing something besides the scenes that
» we don't know about but I doubt it because if they were doing something it
» would have been in the news by now. Most likely they have ended their
» baldness cure ambitions. There is a chance that generic high dose
» bimatoprost will be on the market late this year or early 2013 but it may
» only be somewhat better than minoxidil rather than a huge breakthrough.
» Acell docs could find a way to tweak acell but I doubt it since every time
» I talk to an acell doctor about adding key growth factors they stop the
» line of communication.
»
» I think we are most likely looking at 2014 for a baldness cure unless we
» catch a break from somewhere.



are you being sarcastic again?

Histogen mentioned year 2015 but I doubt it... their previous study wasn't that much of a success




2020 is located in [NA] and he is available to meet: NO


Post reply
jarjarbinx

11.02.2012, 13:26

@ 2020

It looks like 2014 is the year a hair loss cure hits the market.

» » We will likely be able to fly to some other country in 2014 to get our
» hair
» » back via Histogen's treatment. That will likely be the soonest it will
» be
» » released outside of the US. The US will take longer because FDA takes
» » longer than regulatory bodies in some other countries.
» »
» » There is a chance that follica is doing something besides the scenes
» that
» » we don't know about but I doubt it because if they were doing something
» it
» » would have been in the news by now. Most likely they have ended their
» » baldness cure ambitions. There is a chance that generic high dose
» » bimatoprost will be on the market late this year or early 2013 but it
» may
» » only be somewhat better than minoxidil rather than a huge breakthrough.
» » Acell docs could find a way to tweak acell but I doubt it since every
» time
» » I talk to an acell doctor about adding key growth factors they stop the
» » line of communication.
» »
» » I think we are most likely looking at 2014 for a baldness cure unless we
» » catch a break from somewhere.
»
»
»
» are you being sarcastic again?
»
» Histogen mentioned year 2015 but I doubt it... their previous study wasn't
» that much of a success


1. No I'm not being sarcastic. Their previous study was great. They got 73% more new hair plus thickened the existing hair strands. This equals a homerun.


2. They are in phase 2 now and that will either last 6 months or one year. After phase 2 they will be in phase 3 in 2013. Then they will ask for approval in America and that could take a year so it will likely be avilable in America in 2015 but it could hit the market sooner outside of America so i expect it to be available sooner in other countries in 2014.

3. Our only chance to cure hair loss sooner than that is follica, acell, bimatoprost. These 3 things are all looking pretty iffy right now though. Follica completed phase 2 studies about 8 months ago and now we have stopped hearing from them. Most likely they have given up on their baldness cure ambitions. acell looks iffy because the acell docs do not appear willing to add the necessary growth factors to improve on it. Bimatoprost is actually looking like the best chance amongst these 3 iffy possibilities and I personally think that high dose bimatoprost will likely result in a significantly better treatment than minoxidil and we might start seeing generic versions of high dose bimatoprost in early 2013.




jarjarbinx is located in [NA] and he is available to meet: NO


Post reply
2020

11.02.2012, 13:37

@ jarjarbinx

It looks like 2014 is the year a hair loss cure hits the market.

» 1. No I'm not being sarcastic. Their previous study was great. They got
» 73% more new hair plus thickened the existing hair strands. This equals a
» homerun.
»

On a REAL HUMAN PATIENT?
I see 20-25% growth:
http://histogen.com/aboutus/news_events.htm#23



»
» 2. They are in phase 2 now and that will either last 6 months or one year.
» After phase 2 they will be in phase 3 in 2013. Then they will ask for
» approval in America and that could take a year so it will likely be
» avilable in America in 2015 but it could hit the market sooner outside of
» America so i expect it to be available sooner in other countries in 2014.
»

aren't they expecting results from their phase2 in december 2012?
If so, 2014 sounds a bit unrealistic...


» 3. Our only chance to cure hair loss sooner than that is follica, acell,
» bimatoprost. These 3 things are all looking pretty iffy right now though.
» Follica completed phase 2 studies about 8 months ago and now we have
» stopped hearing from them. Most likely they have given up on their
» baldness cure ambitions. acell looks iffy because the acell docs do not
» appear willing to add the necessary growth factors to improve on it.
» Bimatoprost is actually looking like the best chance amongst these 3 iffy
» possibilities and I personally think that high dose bimatoprost will likely
» result in a significantly better treatment than minoxidil and we might
» start seeing generic versions of high dose bimatoprost in early 2013.

bimatoprost is just latisse which is a joke.... someone on hair.l0ss.t@lk tried to use it and it made no improvement in his hair....

follica is on phase3 now.


I'd like to be optimistic but those 2014/2015 deadlines for a "cure" just seem waay to early... 2017 maybe?




2020 is located in [NA] and he is available to meet: NO


Post reply
Iron_Man

11.02.2012, 13:49

@ jarjarbinx

It looks like 2014 is the year a hair loss cure hits the market.

» We will likely be able to fly to some other country in 2014 to get our hair back ...
[image]




Iron_Man is located in [NA] and he is available to meet: NO

---
I documented the world’s 1st day-by-day (HST) donor hair regeneration process …


Post reply
jarjarbinx

11.02.2012, 13:52

@ 2020

It looks like 2014 is the year a hair loss cure hits the market.

1. Note that your Histogen study showing 20-25% more hair growth is the effect after just 3 months. Patients were followed for a year and after one year they had 73% more new hair PLUS thickening of their already existing hair.

2. I do not know when Histogen is expecting results from their current study. I don't know if it's a 6 month or one year study. When Merck was studying propecia they did 6 month studies. I think that minoxidil also did 6 month studies when they first did rogaine. If the Histogen studies are 6 month studies then they could complete phase 2 in mid 2012 and start phase 3 in mid 2012 and then be done with phase 2 the end of this year and release in some foreign countries in 2013. But if Histogen's studies are one year then they would complete phase 2 in Dec 2012 and do phase 3 all throughout 2013 and possibly release in other countries in 2014. Again, I am saying other countries not the US because the USFDA will slow things out to 2015 for a US release.

3. There is no evidence whatsoever that follica is in phase 3. You are the first person to state that. Please provide a link to demonstrate that they've moved into phase 3. I have contacted follica but they do not reply and they have said nothing publicly since they completed their phase 2 almost 8 months ago. I think they've quit their baldness cure ambitions.

4. Latisse is not strong enough for scalp hair. That is why latisse did not work on the guy's scalp. Allergan is testing a stronger version for the scalp. Hideo Uno's study shows that Bimatoprost in a higher-than-Latiss-dose is 100 times as effective as potent as minoxidil. I have hopes that it will be a significant improvement over minoxidil because it is much more powerful than minoxidil.

5. Again, please tell me why you think follica is in phase 3 now?









» » 1. No I'm not being sarcastic. Their previous study was great. They
» got
» » 73% more new hair plus thickened the existing hair strands. This equals
» a
» » homerun.
» »
»
» On a REAL HUMAN PATIENT?
» I see 20-25% growth:
» http://histogen.com/aboutus/news_events.htm#23
»
»
»
» »
» » 2. They are in phase 2 now and that will either last 6 months or one
» year.
» » After phase 2 they will be in phase 3 in 2013. Then they will ask for
» » approval in America and that could take a year so it will likely be
» » avilable in America in 2015 but it could hit the market sooner outside
» of
» » America so i expect it to be available sooner in other countries in
» 2014.
» »
»
» aren't they expecting results from their phase2 in december 2012?
» If so, 2014 sounds a bit unrealistic...
»
»
» » 3. Our only chance to cure hair loss sooner than that is follica,
» acell,
» » bimatoprost. These 3 things are all looking pretty iffy right now though.
»
» » Follica completed phase 2 studies about 8 months ago and now we have
» » stopped hearing from them. Most likely they have given up on their
» » baldness cure ambitions. acell looks iffy because the acell docs do not
» » appear willing to add the necessary growth factors to improve on it.
» » Bimatoprost is actually looking like the best chance amongst these 3
» iffy
» » possibilities and I personally think that high dose bimatoprost will
» likely
» » result in a significantly better treatment than minoxidil and we might
» » start seeing generic versions of high dose bimatoprost in early 2013.
»
» bimatoprost is just latisse which is a joke.... someone on hair.l0ss.t@lk
» tried to use it and it made no improvement in his hair....
»
» follica is on phase3 now.
»
»
» I'd like to be optimistic but those 2014/2015 deadlines for a "cure" just
» seem waay to early... 2017 maybe?




jarjarbinx is located in [NA] and he is available to meet: NO


Post reply
jarjarbinx

11.02.2012, 14:02

@ Iron_Man

It looks like 2014 is the year a hair loss cure hits the market.

» » We will likely be able to fly to some other country in 2014 to get
» our hair back ...
» [image]


Hahaha. I got a kick out of that for sure. LOL!!!




jarjarbinx is located in [NA] and he is available to meet: NO


Post reply
gettingthere

11.02.2012, 14:02

@ 2020

It looks like 2014 is the year a hair loss cure hits the market.

» » 1. No I'm not being sarcastic. Their previous study was great. They
» got
» » 73% more new hair plus thickened the existing hair strands. This equals
» a
» » homerun.
» »
»
» On a REAL HUMAN PATIENT?
» I see 20-25% growth:
» http://histogen.com/aboutus/news_events.htm#23
»
»
»
» »
» » 2. They are in phase 2 now and that will either last 6 months or one
» year.
» » After phase 2 they will be in phase 3 in 2013. Then they will ask for
» » approval in America and that could take a year so it will likely be
» » avilable in America in 2015 but it could hit the market sooner outside
» of
» » America so i expect it to be available sooner in other countries in
» 2014.
» »
»
» aren't they expecting results from their phase2 in december 2012?
» If so, 2014 sounds a bit unrealistic...
»
»
» » 3. Our only chance to cure hair loss sooner than that is follica,
» acell,
» » bimatoprost. These 3 things are all looking pretty iffy right now though.
»
» » Follica completed phase 2 studies about 8 months ago and now we have
» » stopped hearing from them. Most likely they have given up on their
» » baldness cure ambitions. acell looks iffy because the acell docs do not
» » appear willing to add the necessary growth factors to improve on it.
» » Bimatoprost is actually looking like the best chance amongst these 3
» iffy
» » possibilities and I personally think that high dose bimatoprost will
» likely
» » result in a significantly better treatment than minoxidil and we might
» » start seeing generic versions of high dose bimatoprost in early 2013.
»
» bimatoprost is just latisse which is a joke.... someone on hair.l0ss.t@lk
» tried to use it and it made no improvement in his hair....
»
» follica is on phase3 now.
»
»
» I'd like to be optimistic but those 2014/2015 deadlines for a "cure" just
» seem waay to early... 2017 maybe?

I'm gonna have to disagree with you there, you aren't thinking about the billions of dollars at stake here for these companies. I think 2014/15 is just about right and also Histogen's early trial was VERY impressive, one shot of the lowest dose and significant hair growth that lasted and cycled... I can't wrap my head around why anyone would think otherwise to be honest. With companies racing for the goldmine ahead I think the race will start to heat up and they'll try to introduce something to the market ASAP, there are HUGE amounts of money at stake for the winner.




gettingthere is located in [NA] and he is available to meet: NO


Post reply
jarjarbinx

11.02.2012, 14:10

@ gettingthere

It looks like 2014 is the year a hair loss cure hits the market.

» » » 1. No I'm not being sarcastic. Their previous study was great. They
» » got
» » » 73% more new hair plus thickened the existing hair strands. This
» equals
» » a
» » » homerun.
» » »
» »
» » On a REAL HUMAN PATIENT?
» » I see 20-25% growth:
» » http://histogen.com/aboutus/news_events.htm#23
» »
» »
» »
» » »
» » » 2. They are in phase 2 now and that will either last 6 months or one
» » year.
» » » After phase 2 they will be in phase 3 in 2013. Then they will ask
» for
» » » approval in America and that could take a year so it will likely be
» » » avilable in America in 2015 but it could hit the market sooner outside
» » of
» » » America so i expect it to be available sooner in other countries in
» » 2014.
» » »
» »
» » aren't they expecting results from their phase2 in december 2012?
» » If so, 2014 sounds a bit unrealistic...
» »
» »
» » » 3. Our only chance to cure hair loss sooner than that is follica,
» » acell,
» » » bimatoprost. These 3 things are all looking pretty iffy right now
» though.
» »
» » » Follica completed phase 2 studies about 8 months ago and now we have
» » » stopped hearing from them. Most likely they have given up on their
» » » baldness cure ambitions. acell looks iffy because the acell docs do
» not
» » » appear willing to add the necessary growth factors to improve on it.
» » » Bimatoprost is actually looking like the best chance amongst these 3
» » iffy
» » » possibilities and I personally think that high dose bimatoprost will
» » likely
» » » result in a significantly better treatment than minoxidil and we might
» » » start seeing generic versions of high dose bimatoprost in early 2013.
» »
» » bimatoprost is just latisse which is a joke.... someone on
» hair.l0ss.t@lk
» » tried to use it and it made no improvement in his hair....
» »
» » follica is on phase3 now.
» »
» »
» » I'd like to be optimistic but those 2014/2015 deadlines for a "cure"
» just
» » seem waay to early... 2017 maybe?
»
» I'm gonna have to disagree with you there, you aren't thinking about the
» billions of dollars at stake here for these companies. I think 2014/15 is
» just about right and also Histogen's early trial was VERY impressive, one
» shot of the lowest dose and significant hair growth that lasted and
» cycled... I can't wrap my head around why anyone would think otherwise to
» be honest. With companies racing for the goldmine ahead I think the race
» will start to heat up and they'll try to introduce something to the market
» ASAP, there are HUGE amounts of money at stake for the winner.



You're the one who's right. And you're right on every issue you asserted. One thing though: do you think follica is still in the race at all? They completed phase 2 mid-2011 - about 8 months ago. And now we hear nothing from them. It seems to me that if they were pressing forward we would hear something from them. Their silence seems to indicate that they have dropped out of the race and faded away. If they are really in phase 3 then that could speed things up quite a bit. But I can't think of any reason they would for them to be silent if they had good phase 2 results and if they are now in phase 3 studies. Indeed, if they had good phase 2 results and they are now in phase 3 studies then they are ahead of everyone else, they have the inside track to win the race, and it seems to me that they would want to publicize those facts. If they had good phase 2 results and if they are in phase 3 studies, then bald patients would stop getting hair transplants at this point and just wait for follica, which would be avail somewhere in the world by mid 2013, maybe even sooner.

Follica's silence = Follica losing today's customers to HT doctors. I think that if Follica was still in the race we would have heard something from them by now. I think they've likely given up on their baldness cure ambitions.




jarjarbinx is located in [NA] and he is available to meet: NO


Post reply
2020

11.02.2012, 14:53

@ jarjarbinx

It looks like 2014 is the year a hair loss cure hits the market.

» 1. Note that your Histogen study showing 20-25% more hair growth is the
» effect after just 3 months. Patients were followed for a year and after
» one year they had 73% more new hair PLUS thickening of their already
» existing hair.

nvm


»
» 2. I do not know when Histogen is expecting results from their current
» study. I don't know if it's a 6 month or one year study. When Merck was
» studying propecia they did 6 month studies. I think that minoxidil also
» did 6 month studies when they first did rogaine. If the Histogen studies
» are 6 month studies then they could complete phase 2 in mid 2012 and start
» phase 3 in mid 2012 and then be done with phase 2 the end of this year and
» release in some foreign countries in 2013. But if Histogen's studies are
» one year then they would complete phase 2 in Dec 2012 and do phase 3 all
» throughout 2013 and possibly release in other countries in 2014. Again, I
» am saying other countries not the US because the USFDA will slow things out
» to 2015 for a US release.

December 12, 2012. That's their phase 2. Who knows how long it will take for them to completely finish their studies.


»
» 3. There is no evidence whatsoever that follica is in phase 3. You are
» the first person to state that. Please provide a link to demonstrate that
» they've moved into phase 3. I have contacted follica but they do not reply
» and they have said nothing publicly since they completed their phase 2
» almost 8 months ago. I think they've quit their baldness cure ambitions.

follica is a private company...they have no obligation to keep us informed.
Let me look for that "phase 3" link...


»
» 4. Latisse is not strong enough for scalp hair. That is why latisse did
» not work on the guy's scalp. Allergan is testing a stronger version for
» the scalp. Hideo Uno's study shows that Bimatoprost in a
» higher-than-Latiss-dose is 100 times as effective as potent as minoxidil.
» I have hopes that it will be a significant improvement over minoxidil
» because it is much more powerful than minoxidil.
»

stronger? you mean "more of it"? I told you, someone on another forum already tried higher doses for hair growth and it didn't work...
Are the Latisse people even trying to get into hair loss market?




2020 is located in [NA] and he is available to meet: NO


Post reply
jarjarbinx

11.02.2012, 15:04

@ 2020

It looks like 2014 is the year a hair loss cure hits the market.

» » 1. Note that your Histogen study showing 20-25% more hair growth is the
» » effect after just 3 months. Patients were followed for a year and after
» » one year they had 73% more new hair PLUS thickening of their already
» » existing hair.
»
» nvm


What does "nvm" mean? I don't know what you are trying to say to me.


»
»
» »
» » 2. I do not know when Histogen is expecting results from their current
» » study. I don't know if it's a 6 month or one year study. When Merck
» was
» » studying propecia they did 6 month studies. I think that minoxidil also
» » did 6 month studies when they first did rogaine. If the Histogen
» studies
» » are 6 month studies then they could complete phase 2 in mid 2012 and
» start
» » phase 3 in mid 2012 and then be done with phase 2 the end of this year
» and
» » release in some foreign countries in 2013. But if Histogen's studies
» are
» » one year then they would complete phase 2 in Dec 2012 and do phase 3 all
» » throughout 2013 and possibly release in other countries in 2014. Again,
» I
» » am saying other countries not the US because the USFDA will slow things
» out
» » to 2015 for a US release.
»
» December 12, 2012. That's their phase 2. Who knows how long it will take
» for them to completely finish their studies.
»


Well that is my point: neither do I. If Histogen's studies are 6 months long then we could see their technology come to market somewehere in the world in 2013 because phase 2 and phase 3 could both complete by the end of this year and some countries have very short regulatory waiting periods before bringing new treatments to market, and a few countries have NO regulatory waiting periods before bringing new treatments to market. So in some countries Histogen could become avail immediately upon completion of phase 2 or phase 3 studies whenever phase 2 and phase 3 studies complete.





»
» »
» » 3. There is no evidence whatsoever that follica is in phase 3. You are
» » the first person to state that. Please provide a link to demonstrate
» that
» » they've moved into phase 3. I have contacted follica but they do not
» reply
» » and they have said nothing publicly since they completed their phase 2
» » almost 8 months ago. I think they've quit their baldness cure ambitions.
»
» follica is a private company...they have no obligation to keep us
» informed.
» Let me look for that "phase 3" link...
»


I would like to see that link if you can find it. I do not think follica is in phase 3; I think they have abandoned their baldness cure agenda, but I do not know that for sure. I agree that there is a chance that they are still moving forward and i hope that you are right because if they are still in the race, and if they are in phase 3, then that means they might have a worthwhile treatment and if it's already in phase 3 then it could hit the market somewhere in the world in 2013.


»
» »
» » 4. Latisse is not strong enough for scalp hair. That is why latisse
» did
» » not work on the guy's scalp. Allergan is testing a stronger version for
» » the scalp. Hideo Uno's study shows that Bimatoprost in a
» » higher-than-Latiss-dose is 100 times as effective as potent as minoxidil.
»
» » I have hopes that it will be a significant improvement over minoxidil
» » because it is much more powerful than minoxidil.
» »
»
» stronger? you mean "more of it"? I told you, someone on another forum
» already tried higher doses for hair growth and it didn't work...
» Are the Latisse people even trying to get into hair loss market?


The "Latisse people" is a company called Allergan (they also make botox) and they are indeed trying to get into the hair loss market. They have high dose bimatoprost (the same as latisse except stronger) in phase 2 clinical studies right now for scalp hair loss. They began phase 2 in September 2011 and it will complete in September 2012. Some hair loss studies are 6 months while other hair loss studies are 12 months. This one is 12 months.




jarjarbinx is located in [NA] and he is available to meet: NO


Post reply
Iron_Man

11.02.2012, 16:47

@ jarjarbinx

It looks like 2014 is the year a hair loss cure hits the market.

» » » 1. Note that your Histogen study showing 20-25% more hair growth is
» the
» » » effect after just 3 months. Patients were followed for a year and
» after
» » » one year they had 73% more new hair PLUS thickening of their already
» » » existing hair.
» »
» » nvm
»
»
» What does "nvm" mean? I don't know what you are trying to say to me.

never mind




Iron_Man is located in [NA] and he is available to meet: NO

---
I documented the world’s 1st day-by-day (HST) donor hair regeneration process …


Post reply
KO

11.02.2012, 19:58

@ Iron_Man

It looks like 2014 is the year a hair loss cure hits the market.

Histogen is in a Phase I/II Study. They'll likely need to do a IIb study (what Replicel is going to do), then a Phase 3 study, and I believe you need 2 Phase 3 studies.


No Histogen will not release next year in 2013.




KO is located in [NA] and he is available to meet: NO


Post reply
jarjarbinx

11.02.2012, 20:57

@ KO

It looks like 2014 is the year a hair loss cure hits the market.

» Histogen is in a Phase I/II Study. They'll likely need to do a IIb study
» (what Replicel is going to do), then a Phase 3 study, and I believe you
» need 2 Phase 3 studies.
»
»
» No Histogen will not release next year in 2013.


I really doubt it but then first need to know how long the phase present phase 1/2 study is. Also, will they go immediately from phase 1/2 to phase 2b or phase 3, or will they spend a lot of time analyzing the data from phase 1/2 before jumping to the next study. When Merck did propecia study they went straight from phase 2 to phase 3 with NO delay for analysis. The were ready to go straight to phase 3 by the time phase 2 completed. Histogen could do the same thing if they prepare the logistics for the next study now beforehand. They have the money because their last round of financing produced enough money to go through all the studies needed to get HSC to market. Also, it is a guess on your part that they need to do a phase 2b; that is not a certainty. Also, after phase 2 it is possible that they could have enough info to release HSC early in some country where regulatory demands are less rigid.

What do you think about follica's silence? Are you starting to think like me that their silence likely means that they have abandoned their baldness cure ambitions?




jarjarbinx is located in [NA] and he is available to meet: NO


Post reply
gettingthere

11.02.2012, 21:33

@ jarjarbinx

It looks like 2014 is the year a hair loss cure hits the market.

» » » » 1. No I'm not being sarcastic. Their previous study was great.
» They
» » » got
» » » » 73% more new hair plus thickened the existing hair strands. This
» » equals
» » » a
» » » » homerun.
» » » »
» » »
» » » On a REAL HUMAN PATIENT?
» » » I see 20-25% growth:
» » » http://histogen.com/aboutus/news_events.htm#23
» » »
» » »
» » »
» » » »
» » » » 2. They are in phase 2 now and that will either last 6 months or
» one
» » » year.
» » » » After phase 2 they will be in phase 3 in 2013. Then they will ask
» » for
» » » » approval in America and that could take a year so it will likely be
» » » » avilable in America in 2015 but it could hit the market sooner
» outside
» » » of
» » » » America so i expect it to be available sooner in other countries in
» » » 2014.
» » » »
» » »
» » » aren't they expecting results from their phase2 in december 2012?
» » » If so, 2014 sounds a bit unrealistic...
» » »
» » »
» » » » 3. Our only chance to cure hair loss sooner than that is follica,
» » » acell,
» » » » bimatoprost. These 3 things are all looking pretty iffy right now
» » though.
» » »
» » » » Follica completed phase 2 studies about 8 months ago and now we have
» » » » stopped hearing from them. Most likely they have given up on their
» » » » baldness cure ambitions. acell looks iffy because the acell docs do
» » not
» » » » appear willing to add the necessary growth factors to improve on it.
»
» » » » Bimatoprost is actually looking like the best chance amongst these 3
» » » iffy
» » » » possibilities and I personally think that high dose bimatoprost will
» » » likely
» » » » result in a significantly better treatment than minoxidil and we
» might
» » » » start seeing generic versions of high dose bimatoprost in early
» 2013.
» » »
» » » bimatoprost is just latisse which is a joke.... someone on
» » hair.l0ss.t@lk
» » » tried to use it and it made no improvement in his hair....
» » »
» » » follica is on phase3 now.
» » »
» » »
» » » I'd like to be optimistic but those 2014/2015 deadlines for a "cure"
» » just
» » » seem waay to early... 2017 maybe?
» »
» » I'm gonna have to disagree with you there, you aren't thinking about the
» » billions of dollars at stake here for these companies. I think 2014/15
» is
» » just about right and also Histogen's early trial was VERY impressive,
» one
» » shot of the lowest dose and significant hair growth that lasted and
» » cycled... I can't wrap my head around why anyone would think otherwise
» to
» » be honest. With companies racing for the goldmine ahead I think the
» race
» » will start to heat up and they'll try to introduce something to the
» market
» » ASAP, there are HUGE amounts of money at stake for the winner.
»
»
»
» You're the one who's right. And you're right on every issue you asserted.
» One thing though: do you think follica is still in the race at all? They
» completed phase 2 mid-2011 - about 8 months ago. And now we hear nothing
» from them. It seems to me that if they were pressing forward we would hear
» something from them. Their silence seems to indicate that they have
» dropped out of the race and faded away. If they are really in phase 3 then
» that could speed things up quite a bit. But I can't think of any reason
» they would for them to be silent if they had good phase 2 results and if
» they are now in phase 3 studies. Indeed, if they had good phase 2 results
» and they are now in phase 3 studies then they are ahead of everyone else,
» they have the inside track to win the race, and it seems to me that they
» would want to publicize those facts. If they had good phase 2 results and
» if they are in phase 3 studies, then bald patients would stop getting hair
» transplants at this point and just wait for follica, which would be avail
» somewhere in the world by mid 2013, maybe even sooner.
»
» Follica's silence = Follica losing today's customers to HT doctors. I
» think that if Follica was still in the race we would have heard something
» from them by now. I think they've likely given up on their baldness cure
» ambitions.

I'm not too sure about Follica, one can only speculate because they are very private about their studies but as for the rest I can only assume that every year the pressure is building to find a cure, it's a race to the finish, if Histogen is compoundable and works these other companies are in big trouble.




gettingthere is located in [NA] and he is available to meet: NO


Post reply
jarjarbinx

11.02.2012, 21:50

@ gettingthere

It looks like 2014 is the year a hair loss cure hits the market.

» » » » » 1. No I'm not being sarcastic. Their previous study was great.
» » They
» » » » got
» » » » » 73% more new hair plus thickened the existing hair strands. This
» » » equals
» » » » a
» » » » » homerun.
» » » » »
» » » »
» » » » On a REAL HUMAN PATIENT?
» » » » I see 20-25% growth:
» » » » http://histogen.com/aboutus/news_events.htm#23
» » » »
» » » »
» » » »
» » » » »
» » » » » 2. They are in phase 2 now and that will either last 6 months or
» » one
» » » » year.
» » » » » After phase 2 they will be in phase 3 in 2013. Then they will
» ask
» » » for
» » » » » approval in America and that could take a year so it will likely
» be
» » » » » avilable in America in 2015 but it could hit the market sooner
» » outside
» » » » of
» » » » » America so i expect it to be available sooner in other countries
» in
» » » » 2014.
» » » » »
» » » »
» » » » aren't they expecting results from their phase2 in december 2012?
» » » » If so, 2014 sounds a bit unrealistic...
» » » »
» » » »
» » » » » 3. Our only chance to cure hair loss sooner than that is follica,
» » » » acell,
» » » » » bimatoprost. These 3 things are all looking pretty iffy right now
» » » though.
» » » »
» » » » » Follica completed phase 2 studies about 8 months ago and now we
» have
» » » » » stopped hearing from them. Most likely they have given up on
» their
» » » » » baldness cure ambitions. acell looks iffy because the acell docs
» do
» » » not
» » » » » appear willing to add the necessary growth factors to improve on
» it.
» »
» » » » » Bimatoprost is actually looking like the best chance amongst these
» 3
» » » » iffy
» » » » » possibilities and I personally think that high dose bimatoprost
» will
» » » » likely
» » » » » result in a significantly better treatment than minoxidil and we
» » might
» » » » » start seeing generic versions of high dose bimatoprost in early
» » 2013.
» » » »
» » » » bimatoprost is just latisse which is a joke.... someone on
» » » hair.l0ss.t@lk
» » » » tried to use it and it made no improvement in his hair....
» » » »
» » » » follica is on phase3 now.
» » » »
» » » »
» » » » I'd like to be optimistic but those 2014/2015 deadlines for a "cure"
» » » just
» » » » seem waay to early... 2017 maybe?
» » »
» » » I'm gonna have to disagree with you there, you aren't thinking about
» the
» » » billions of dollars at stake here for these companies. I think
» 2014/15
» » is
» » » just about right and also Histogen's early trial was VERY impressive,
» » one
» » » shot of the lowest dose and significant hair growth that lasted and
» » » cycled... I can't wrap my head around why anyone would think
» otherwise
» » to
» » » be honest. With companies racing for the goldmine ahead I think the
» » race
» » » will start to heat up and they'll try to introduce something to the
» » market
» » » ASAP, there are HUGE amounts of money at stake for the winner.
» »
» »
» »
» » You're the one who's right. And you're right on every issue you
» asserted.
» » One thing though: do you think follica is still in the race at all?
» They
» » completed phase 2 mid-2011 - about 8 months ago. And now we hear
» nothing
» » from them. It seems to me that if they were pressing forward we would
» hear
» » something from them. Their silence seems to indicate that they have
» » dropped out of the race and faded away. If they are really in phase 3
» then
» » that could speed things up quite a bit. But I can't think of any reason
» » they would for them to be silent if they had good phase 2 results and if
» » they are now in phase 3 studies. Indeed, if they had good phase 2
» results
» » and they are now in phase 3 studies then they are ahead of everyone
» else,
» » they have the inside track to win the race, and it seems to me that they
» » would want to publicize those facts. If they had good phase 2 results
» and
» » if they are in phase 3 studies, then bald patients would stop getting
» hair
» » transplants at this point and just wait for follica, which would be
» avail
» » somewhere in the world by mid 2013, maybe even sooner.
» »
» » Follica's silence = Follica losing today's customers to HT doctors. I
» » think that if Follica was still in the race we would have heard
» something
» » from them by now. I think they've likely given up on their baldness
» cure
» » ambitions.
»
» I'm not too sure about Follica, one can only speculate because they are
» very private about their studies but as for the rest I can only assume that
» every year the pressure is building to find a cure, it's a race to the
» finish, if Histogen is compoundable and works these other companies are in
» big trouble.



The first company to hit the market with a real breakthrough will get most of the business. You see, there are right now a huge number of people waiting for a cure and the first company to hit the market with a real breakthrough will clean house. They will get the huge pent-up demand. We bald people will form long lines outside their door and they will give almost all of us our hair back and then there won't be many bald people left. Other companies will follow that company but those other companies will just get a share of the new people who are just starting to go bald because the first company that came out with the breakthrough treatment already will have gotten all of the pent-up business and they will have made a killing - an absolutely unimaginable amount of money. Since the first company will have done all of the pent-up business they will also have established their treatment because there will be millions and millions and millions of us former bald people giving that first company excellent word of mouth advertising. They will be considered the go-to company/treatment when it comes to getting your hair back. Other breakthrough treatments will have to fight for marketshare from this one company that hit the marketplace first.

It's a mistake to be second into the marketplace with a breakthrough treatment. The company that is first will get all the pent-up demand and will also become entrenched as the market leader with companies that lag behind having to fight for any marketshare.

Since being first is so important if Follica did get good phase 2 results, and really is in phase 3 they should say so publicly because if that is the case then they are in the driver's seat and they can't be overtaken since the closest other companies are is phase 2 and follica may be in phase 3. Even if they can only increase hair counts by 50% that is still revolutionary because the best FDA treatment avail now (minoxidil + propecia/dutasteride) only increases hair counts by maybe 20%. So 50% is a major step forward. Plus if we could increase hair counts by 50% with follica then we might also be able to add minoxidil/dutasteride/propecia and add even more for a better cuulative yield. So if Follica has only a 50% increase in hair counts that may not be as good as Histogen but a 50% increase in hair counts would get us baldies lined up outside their doors clamoring for the Follica treatment so Follica would be wise to get it into the marketplace asap. A 50% increase in hair counts would be a major breakthrough that would get us scrambling for their treatment.




jarjarbinx is located in [NA] and he is available to meet: NO


Post reply
KO

11.02.2012, 22:25

@ jarjarbinx

It looks like 2014 is the year a hair loss cure hits the market.

» I really doubt it but then first need to know how long the phase present
» phase 1/2 study is. Also, will they go immediately from phase 1/2 to phase
» 2b or phase 3, or will they spend a lot of time analyzing the data from
» phase 1/2 before jumping to the next study. When Merck did propecia study
» they went straight from phase 2 to phase 3 with NO delay for analysis. The
» were ready to go straight to phase 3 by the time phase 2 completed.
» Histogen could do the same thing if they prepare the logistics for the next
» study now beforehand. They have the money because their last round of
» financing produced enough money to go through all the studies needed to get
» HSC to market. Also, it is a guess on your part that they need to do a
» phase 2b; that is not a certainty. Also, after phase 2 it is possible that
» they could have enough info to release HSC early in some country where
» regulatory demands are less rigid.
»
» What do you think about follica's silence? Are you starting to think like
» me that their silence likely means that they have abandoned their baldness
» cure ambitions?


The reason Merck could move so quickly because fin had already been approved for BPH and they had a good idea about its safety profile etc. They were merely getting it approved for a new indication rather than it being a NDA. Histogen is developing a biologic, for a totally new treatment with an unknown safety profile. The process will not be as quick as Propecia.


I think Follica has to work on developing a device before they can really go through with Phase 3 trials. You cannot patent a process, so they'll develop a device.




KO is located in [NA] and he is available to meet: NO


Post reply
samt23

12.02.2012, 02:48

@ KO

It looks like 2014 is the year a hair loss cure hits the market.

I love how everybody says Follica is in Phase 3 yet they can't prove it.




samt23 is located in [NA] and he is available to meet: NO


Post reply
Sceptic

14.02.2012, 12:24

@ jarjarbinx

It looks like 2014 is the year a hair loss cure hits the market.

» I think we are most likely looking at 2014 for a baldness cure unless we
» catch a break from somewhere.

Maneless, do yourself a favor and go back to your lunatic asylum, thank you!!




Sceptic is located in [NA] and he is available to meet: NO


Post reply
gettingthere

14.02.2012, 13:14

@ Sceptic

It looks like 2014 is the year a hair loss cure hits the market.

» » I think we are most likely looking at 2014 for a baldness cure unless we
» » catch a break from somewhere.
»
» Maneless, do yourself a favor and go back to your lunatic asylum,
» thank you!!

I'm not gonna stoop to your level and say anything negative about you but there is a good chance that something will be released by 2014... I don't know if it will be an all out cure but if your gonna make useless comments like these, keep it to yourself.




gettingthere is located in [NA] and he is available to meet: NO


Post reply
jarjarbinx

14.02.2012, 13:18

@ Sceptic

It looks like 2014 is the year a hair loss cure hits the market.

» » I think we are most likely looking at 2014 for a baldness cure unless we
» » catch a break from somewhere.
»
» Maneless, do yourself a favor and go back to your lunatic asylum,
» thank you!!


What a peanut-gallery stooge.

You are stupid and ignorant and you belong up in a tree eating bananas.




jarjarbinx is located in [NA] and he is available to meet: NO


Post reply
roger_that

MARYLAND,
14.02.2012, 14:52

@ jarjarbinx

It looks like 2014 is the year a hair loss cure hits the market.

Jarjarbinx, I'd like to think 2014 will be the year, and you make some good points, BUT...

First of all I want to say that I would be among the first to travel anywhere on this globe to get my hair back. I have absolutely no problem going and I would go if I knew there was a real cure. If I have to fly to Singapore, I'll fly to Singapore. Always wanted to go there, anyway!

HOWEVER, while I feel somewhat optimistic now about Histogen's ability to grow some hair, I think technical or logistical problems might prevent a lot of Americans from taking advantage of it, if it's only approved outside North America.

First, we have to be very careful about understanding what Histogen is, and what it is not.

I don't think Histogen is the kind of treatment where you go in, get one dose of injections on one day, and then an abundance of hair sprouts on your head all of a sudden, and you're cured for life. Remember, we're talking about an injectible medication here.

Most people seem to believe Histogen will work something like this: You go to the doctor, he injects the balding areas of your scalp with Histogen.... maybe you get 10-20 or even 30 injections on your head that day. OK, then you wait...

After a few weeks to a month, maybe you'll see some hair growing. After about 3 months, maybe you'll see a substantial amount of hair growing, as in Histogen's widely-published "best case scenario" photo. And then you're set for life, or for a very, very long time, and your worries are over.

But I think it's more likely that you'll have to get a wave of regular injections to grow substantial hair. In other words, optimum results won't come from just getting one treatment. To really grow substantial hair, the optimum treatment regimen for this product will probably be a course of many months of treatments, with patients perhaps having to return to the doctor's clinic maybe once every several weeks. This is more realistic because, remember, Histogen is NOT a live cell-based product, it is an INJECTIBLE MEDICATION which will rapidly degrade in the body once injected, so to keep tissue titers of the medication up to clinically-effective levels, I imagine there will have to be a regular course of repeat therapy with follow-up shots every few weeks for a while, and then regular booster shots thereafter, maybe every 3-6 months.

If the treatment is only available in, say, Singapore or Southeast Asia at first, then how are Americans going to be able to take advantage of that?

I'm just sayin'...




roger_that is located in MARYLAND and he is available to meet: YES
email hairsite@aol.com to arrange a meeting.


Post reply
KO

14.02.2012, 19:09

@ roger_that

It looks like 2014 is the year a hair loss cure hits the market.

No way on earth a 2nd-generation MPB treatment will be out by 2014, a 1st-gen treatment like bimatoprost or perhaps a topical antiandrogen like ASC-J9 may come out, but nothing 2nd-gen, AKA growing new follicles from scratch.


Histogen and Replicel have to do a Phase 2B trial, ARI needs to finish up its Phase 2 trial, and Follica needs to get a device approved. ARI is the furthest ahead when it comes to cell-based solutions, and their P2 doesn't finish till 2013. After which they'll do a Phase 3 trial which shouldn't start till 2014 at the earliest. And we don't know how long the FDA is going to take to approve these things.

Histogen, ARI, and Replicel are doing it under FDA oversight I believe, whereas Follica appears to be doing it through the European pathway, maybe one of them could release it outside the US first, but even then 2014 is too early.




KO is located in [NA] and he is available to meet: NO


Post reply
nsmnyc

14.02.2012, 20:43

@ KO

It looks like 2014 is the year a hair loss cure hits the market.

» I think Follica has to work on developing a device before they can really
» go through with Phase 3 trials. You cannot patent a process, so they'll
» develop a device.

Yes you can, one of the main patent routes is for a "utility" patent, of which "process" falls under. I know this from my own research and the start of filing one, but here is the link to prove it:

http://www.uspto.gov/web/offices/ac/ido/oeip/taf/patdesc.htm




nsmnyc is located in [NA] and he is available to meet: NO


Post reply
roger_that

MARYLAND,
14.02.2012, 20:44

@ KO

It looks like 2014 is the year a hair loss cure hits the market.

» Histogen, ARI, and Replicel are doing it under FDA oversight I believe,
» whereas Follica appears to be doing it through the European pathway, maybe
» one of them could release it outside the US first, but even then 2014 is
» too early.

KO, normally I respect your opinions even though we often disagree, but I'm afraid to say that in your comments in this post (all of them), I'm shocked at how you're just repudiating REALITY... ignoring the facts completely and substituting your own version of the facts.

HISTOGEN AND REPLICEL ARE NOT CONDUCTING THESE TRIALS IN THE U.S.

NOR ARE THEY CONDUCTING THEM UNDER U.S. SUPERVISION.... PERIOD!!!


The Replicel CEO did mention that they are conducting their trials, in the Republic of Georgia, according to FDA STANDARDS... but NOT under the auspices, supervision, or oversight of the FDA, and NOT under an FDA-imposed timeline.

They are simply conforming to FDA standards so that WHEN they submit the results to the FDA in the US, and apply to do US-based trials (which are almost certain to be required, of course), they will be ready with the clinical evidence, and the whole application process will go that much faster and smoother.

I don't know how much more simple I have to make it. THESE TRIALS ARE BEING CONDUCTED OUTSIDE OF U.S. JURISDICTION, UNDER FOREIGN LAWS WHICH ENABLE THEM TO DO EVERYTHING MORE QUICKLY.

Please go back and watch the videos of the Replicel CEO again, and listen closely to what the man is saying.

No, it's no guarantee of any of this becoming available in 2014, but it seems to me you're just blatantly ignoring the facts here, for both companies.

If these companies conduct successful clinical trials in their host countries, then their treatments will almost certainly become available in those host countries MUCH SOONER THAN IN THE U.S. Also, approval in these host countries will "bleed over" into neighboring countries and regions adjacent to the host countries, because countries generally share regional similarities in research and clinical standards and commercial markets.

If these companies wanted to wait and do things according to the FDA timeline, THEN THEY WOULDN'T BE DOING TRIALS IN THESE FOREIGN COUNTRIES IN THE FIRST PLACE.




roger_that is located in MARYLAND and he is available to meet: YES
email hairsite@aol.com to arrange a meeting.


Post reply
KO

14.02.2012, 21:01

@ roger_that

It looks like 2014 is the year a hair loss cure hits the market.

Then why are they registered on a US government website? www.clinicaltrials.gov ?

Histogen, ARI, and Replicel are there. Follica however is not. Follica actually does appear to be conducting outside the auspices of the FDA otherwise they'd show up as well.




KO is located in [NA] and he is available to meet: NO


Post reply
KO

14.02.2012, 21:06

@ nsmnyc

It looks like 2014 is the year a hair loss cure hits the market.

» » I think Follica has to work on developing a device before they can
» really
» » go through with Phase 3 trials. You cannot patent a process, so they'll
» » develop a device.
»
» Yes you can, one of the main patent routes is for a "utility" patent, of
» which "process" falls under. I know this from my own research and the start
» of filing one, but here is the link to prove it:
»
» http://www.uspto.gov/web/offices/ac/ido/oeip/taf/patdesc.htm

I'm pretty confident that in medicine, patents on processes are no longer tenable since the early 90s.

Now assuming they were, how on earth can you patent it? It's basically surgery. You can go get dermabrasion on your scalp at the derm's office, come home and then apply lithium yourself. Where would be the profit in that?




KO is located in [NA] and he is available to meet: NO


Post reply
KO

14.02.2012, 21:11

@ KO

It looks like 2014 is the year a hair loss cure hits the market.

You might be right actually, I think some tests are patented, but I don't believe surgical procedures are.




KO is located in [NA] and he is available to meet: NO


Post reply
roger_that

MARYLAND,
14.02.2012, 21:19
(edited by roger_that, 14.02.2012, 21:48)

@ KO

It looks like 2014 is the year a hair loss cure hits the market.

» Then why are they registered on a US government website?
» www.clinicaltrials.gov ?
»
» Histogen, ARI, and Replicel are there. Follica however is not. Follica
» actually does appear to be conducting outside the auspices of the FDA
» otherwise they'd show up as well.


Histogen is there. But their MAIN trials location is Singapore. It's to their interest to also register in the US, but the trials in Singapore have nothing to do with any trials being conducted, or planned, in the US. The US has ZERO jurisdiction or influence over clinical trials in Singapore. There is no administrative connection. Singapore is a sovereign country.

I don't see Replicel there, but even if they were, the exact same thing I wrote above about Histogen applies. Plus, Replicel is not even a U.S.-based company, like Histogen is.

It would make sense for Histogen to be on that database, after all, it is a U.S.-based company. Even if they're not conducting trials now in the U.S., it looks like they've applied to do so, at least. The Histogen entry says their trial is "active, not recruiting". Who knows what that means? Who knows where in the US their trail is really being held, or if it is even being held. However, they're making a lot of fanfare about their trial in Singapore. That one, at least, we KNOW is real.

ARI isn't an issue at all because we know they're currently conducting clinical trials in the US.

Plus -- and this applies to all 3 of the above -- making trials public on clinicaltrials.gov is optional, not mandatory. I think that the appearance of trials on the database means very little -- trials can be conducted without them appearing on the database, and conversely, just because trials are mentioned on the database doesn't mean they're actually being conducted right now.




roger_that is located in MARYLAND and he is available to meet: YES
email hairsite@aol.com to arrange a meeting.


Post reply
KO

14.02.2012, 23:04

@ roger_that

It looks like 2014 is the year a hair loss cure hits the market.

That's a fair point, it may be registered in the US with the intention of complying with US standards but done outside US jurisdiction.

»
» Plus -- and this applies to all 3 of the above -- making trials public on
» clinicaltrials.gov is optional, not mandatory. I think that the appearance
» of trials on the database means very little -- trials can be conducted
» without them appearing on the database, and conversely, just because trials
» are mentioned on the database doesn't mean they're actually being conducted
» right now.

I don't believe this is true, but could be.




KO is located in [NA] and he is available to meet: NO


Post reply
Anomaly

19.02.2012, 01:46

@ jarjarbinx

It looks like 2014 is the year a hair loss cure hits the market.

The thing I'm most concerned about is why you chose jarjarbinx as your forum name?




Anomaly is located in [NA] and he is available to meet: NO


Post reply
jarjarbinx

20.02.2012, 18:08

@ roger_that

It looks like 2014 is the year a hair loss cure hits the market.

» Jarjarbinx, I'd like to think 2014 will be the year, and you make some good
» points, BUT...
»
» First of all I want to say that I would be among the first to travel
» anywhere on this globe to get my hair back. I have absolutely no problem
» going and I would go if I knew there was a real cure. If I have to fly to
» Singapore, I'll fly to Singapore. Always wanted to go there, anyway!
»
» HOWEVER, while I feel somewhat optimistic now about Histogen's ability to
» grow some hair, I think technical or logistical problems might prevent a
» lot of Americans from taking advantage of it, if it's only approved outside
» North America.
»
» First, we have to be very careful about understanding what Histogen is, and
» what it is not.
»
» I don't think Histogen is the kind of treatment where you go in, get one
» dose of injections on one day, and then an abundance of hair sprouts on
» your head all of a sudden, and you're cured for life. Remember, we're
» talking about an injectible medication here.
»
» Most people seem to believe Histogen will work something like this: You go
» to the doctor, he injects the balding areas of your scalp with Histogen....
» maybe you get 10-20 or even 30 injections on your head that day. OK, then
» you wait...
»
» After a few weeks to a month, maybe you'll see some hair growing. After
» about 3 months, maybe you'll see a substantial amount of hair growing, as
» in Histogen's widely-published "best case scenario" photo. And then
» you're set for life, or for a very, very long time, and your worries are
» over.
»
» But I think it's more likely that you'll have to get a wave of regular
» injections to grow substantial hair. In other words, optimum results
» won't come from just getting one treatment. To really grow substantial
» hair, the optimum treatment regimen for this product will probably be a
» course of many months of treatments, with patients perhaps having to return
» to the doctor's clinic maybe once every several weeks. This is more
» realistic because, remember, Histogen is NOT a live cell-based product, it
» is an INJECTIBLE MEDICATION which will rapidly degrade in the body once
» injected, so to keep tissue titers of the medication up to
» clinically-effective levels, I imagine there will have to be a regular
» course of repeat therapy with follow-up shots every few weeks for a while,
» and then regular booster shots thereafter, maybe every 3-6 months.
»
» If the treatment is only available in, say, Singapore or Southeast Asia at
» first, then how are Americans going to be able to take advantage of that?
»
» I'm just sayin'...




And you have raised an excellent point. I know it's an excellent point because I myself have been concerned about the same thing. I think we have to wait to see their phase 2 results before we can figure out exactly what we will do. One thing I was thinking is that I would go to Singapore for a month (take a paid one month leave from work) and get an injection when I get there and another injection on my last day there. What do you think?




jarjarbinx is located in [NA] and he is available to meet: NO


Post reply
jarjarbinx

20.02.2012, 18:11

@ KO

It looks like 2014 is the year a hair loss cure hits the market.

» No way on earth a 2nd-generation MPB treatment will be out by 2014, a
» 1st-gen treatment like bimatoprost or perhaps a topical antiandrogen like
» ASC-J9 may come out, but nothing 2nd-gen, AKA growing new follicles from
» scratch.
»
»
» Histogen and Replicel have to do a Phase 2B trial, ARI needs to finish up
» its Phase 2 trial, and Follica needs to get a device approved. ARI is the
» furthest ahead when it comes to cell-based solutions, and their P2 doesn't
» finish till 2013. After which they'll do a Phase 3 trial which shouldn't
» start till 2014 at the earliest. And we don't know how long the FDA
» is going to take to approve these things.
»
» Histogen, ARI, and Replicel are doing it under FDA oversight I believe,
» whereas Follica appears to be doing it through the European pathway, maybe
» one of them could release it outside the US first, but even then 2014 is
» too early.


I disagree. Even if phase two is a full year long it would still be done by the end of this year. Then they would do phase 3 next year (2013)and release the following year (2014) someplace like Singapore. And keep in mind that the phase 2 and phase 3 studies may only be 6 months instead of a full year and if they are only 6 months that could speed things up dramatically.




jarjarbinx is located in [NA] and he is available to meet: NO


Post reply
jarjarbinx

20.02.2012, 18:16

@ KO

It looks like 2014 is the year a hair loss cure hits the market.

» That's a fair point, it may be registered in the US with the intention of
» complying with US standards but done outside US jurisdiction.
»
» »
» » Plus -- and this applies to all 3 of the above -- making trials public
» on
» » clinicaltrials.gov is optional, not mandatory. I think that the
» appearance
» » of trials on the database means very little -- trials can be conducted
» » without them appearing on the database, and conversely, just because
» trials
» » are mentioned on the database doesn't mean they're actually being
» conducted
» » right now.
»
» I don't believe this is true, but could be.


Now you understand.

Histogen is doing their studies outside the United States but they are conducting their studies in a manner that is acceptable to the US so that they can use those studies in their submission to the FDA for marketing in the United States. They are allowed to do this.




jarjarbinx is located in [NA] and he is available to meet: NO


Post reply
Iron_Man

20.02.2012, 18:22

@ jarjarbinx

It looks like 2014 is the year a hair loss cure hits the market.

» And keep in
» mind that the phase 2 and phase 3 studies may only be 6 months instead of a
» full year and if they are only 6 months that could speed things up
» dramatically.

hmmmm, I think your calculation (or call it "wet dream calculation";) is a litte bit wrong - because for all these types of procedures ("cell-based procedures" or "serum-stuff" whatever), you need A MINIUM of at least ~18 month to make clear final conclusions and facts about success or failure - especially for hair growth medications. You simply can't make any hard facts conclusions just after 6 month - not even 12 month. The problem are not any medical trails organizations or something, the problem is rather the nature/biology of hair growth - so to speak.




Iron_Man is located in [NA] and he is available to meet: NO

---
I documented the world’s 1st day-by-day (HST) donor hair regeneration process …


Post reply
jarjarbinx

20.02.2012, 18:35

@ Iron_Man

It looks like 2014 is the year a hair loss cure hits the market.

» » And keep in
» » mind that the phase 2 and phase 3 studies may only be 6 months instead of
» a
» » full year and if they are only 6 months that could speed things up
» » dramatically.
»
» hmmmm, I think your calculation (or call it "wet dream calculation";) is a
» litte bit wrong - because for all these types of procedures ("cell-based
» procedures" or "serum-stuff" whatever), you need A MINIUM of at least
» ~18 month to make clear final conclusions and facts about success or
» failure - especially for hair growth medications. You simply can't make any
» hard facts conclusions just after 6 month - not even 12 month. The problem
» are not any medical trails organizations or something, the problem is
» rather the nature/biology of hair growth - so to speak.


Give me a break Iron_man. Propecia went straight from phase 2 to phase 3 with no time in between. It can be done. And Merck was compiling evidence all along so Merck submitted to FDA for approval immediatly upon completion.




jarjarbinx is located in [NA] and he is available to meet: NO


Post reply
KO

20.02.2012, 19:44

@ jarjarbinx

It looks like 2014 is the year a hair loss cure hits the market.

»
» Give me a break Iron_man. Propecia went straight from phase 2 to phase 3
» with no time in between. It can be done. And Merck was compiling evidence
» all along so Merck submitted to FDA for approval immediatly upon
» completion.


Propecia had already been approved for BPH, much easier to approve for a secondary indication rather than going the new route. Now, being in Singapore may totally speed everything up, but who knows. I'll believe it when Phase 3 starts...




KO is located in [NA] and he is available to meet: NO


Post reply
jarjarbinx

21.02.2012, 10:26

@ KO

It looks like 2014 is the year a hair loss cure hits the market.

» »
» » Give me a break Iron_man. Propecia went straight from phase 2 to phase
» 3
» » with no time in between. It can be done. And Merck was compiling
» evidence
» » all along so Merck submitted to FDA for approval immediatly upon
» » completion.
»
»
» Propecia had already been approved for BPH, much easier to approve for a
» secondary indication rather than going the new route. Now, being in
» Singapore may totally speed everything up, but who knows. I'll believe it
» when Phase 3 starts.


bimatprost for hair loss just went from phase 1 to phase 2 with no lag time in between. It depends on the company. It the company is efficient and if they are on the ball and if they are collecting, analyzing, and compiling data as they go along then they can go from one study to the next with little or no lag time. So far Histogen's operations have not been impressive but they may be hunkering down. I think they will likely go from phase 2 to 3 with little or no lag time. That's just my feel for the situation. I think there is competition to be the first out with a new breakthrough treatment and I think they are going to stop wasting time here shortly.




jarjarbinx is located in [NA] and he is available to meet: NO


Post reply
moawk

Germany,
02.03.2012, 22:23

@ jarjarbinx

It looks like 2014 is the year a hair loss cure hits the market.

» We will likely be able to fly to some other country in 2014 to get our hair
» back via Histogen's treatment. That will likely be the soonest it will be
» released outside of the US. The US will take longer because FDA takes
» longer than regulatory bodies in some other countries.
»
» There is a chance that follica is doing something besides the scenes that
» we don't know about but I doubt it because if they were doing something it
» would have been in the news by now. Most likely they have ended their
» baldness cure ambitions. There is a chance that generic high dose
» bimatoprost will be on the market late this year or early 2013 but it may
» only be somewhat better than minoxidil rather than a huge breakthrough.
» Acell docs could find a way to tweak acell but I doubt it since every time
» I talk to an acell doctor about adding key growth factors they stop the
» line of communication.
»
» I think we are most likely looking at 2014 for a baldness cure unless we
» catch a break from somewhere.

Lol at this post, you are very optimistic. I believe in 2014 we will laugh at this post, the only difference some of us will be norwood 7s by that time.




moawk is located in GERMANY and he is available to meet: NO

---
1. Predicted the failure of replicel, months in advance.
2. Predicted how their stock would rise/drop even with exact numbers.
3. Predicted the wild claims and crazyness that gc83uk's donor regeneration will cause among the HT industry during this summer. Including rassman's opinion, Dr. Woods special patients and Pro hair clinic photos.
4. Predicted Gho will open up a clinic in asia.
5. No prediction on Histogen. Looks promising if they didn't fake results.
6. Predicted the only viable HM technique other than Gho would surface when hairs are: "generated through the appropriate cell populations" -Team Tokyo 2012


[image]
- Moawk

Advice for patients: If you are considering a hair transplant, only consider Gho's HST and nothing else. First HT treatment in the world that offers: zero scarring, small downtime and donor regrowth.
http://www.hasci.com

Advice for Investors in HM: Invest in Team Tokyo.
http://www.tsuji-lab.com/en/research/organ/hair.html
Ditch replicel, aderans. They are done for and have no future.


Post reply
Freddie555

03.03.2012, 06:25

@ moawk

It looks like 2014 is the year a hair loss cure hits the market.

» Lol at this post, you are very optimistic. I believe in 2014 we will laugh
» at this post, the only difference some of us will be norwood 7s by that
» time.

i've seen these time lines come & go sadly.

people enthusiastically wait for a cure year after year only to find the company goes under, the stuff does not work or it was all hype.

meanwhile they watch their life tick by.

maybe we are like people in the 1960s who thought the cure was just 5 years away. Imagine their horror if they were told that even half a century later, there would be no cure and they would die bald.




Freddie555 is located in [NA] and he is available to meet: NO

---
"When true Hair Multiplication comes, it will arise out of the East." - John The Revelator, Feb. 18, 2001


Post reply
cal

03.03.2012, 23:49

@ Freddie555

It looks like 2014 is the year a hair loss cure hits the market.

Nobody was in human clinical trials in the 1960s. Nobody was even there in the 1990s for that matter.

Now several operations are roughly near the end of stage#2. That's a pretty big difference.




cal is located in [NA] and he is available to meet: NO


Post reply
Freddie555

04.03.2012, 05:30

@ cal

It looks like 2014 is the year a hair loss cure hits the market.

Consider the number of companies & researchers doing cancer research. Its gotta be many thousands and this has been going on since the 1950s. Tons of donations & fund raisers pour in every year, tons of big name pharma companies researching it, tons of govt money channeled towards it.

Yet there is no cure.

You will however on any given week read news on how a breakthrough in cancer research has occured. But still no cure.

Now consider how FEW companies & researchers are doing hair loss research. Not a single big name pharma here. Zero govt funding and anemic academic research. No global fund raisers or big donors. You can literally count them on your hands. I quickly get a sense of how LOW the odds are that we will be cured within our lifetimes, nevermind 10 to 15 years.

As if that weren't enough, the FEW researchers who volunteer their time & energy towards helping us find a treatment/cure end up being attacked by wild monkeys (refer to the Astressin-B Norma trials). That makes the LOW odds of finding a cure even lower.

I hate to be a wet blanket but sometimes i feel we are hoping against hope here. We are shipwrecked in the middle of the Atlantic ocean and swimming in strong current hoping that an island is just over the horizon. The reality is the island may well be a 1000 miles away and we will be fish food by dawn. No matter what the f&ck we do we are going to drown. The only good news is that the monkeys will hopefully drown with us.




Freddie555 is located in [NA] and he is available to meet: NO

---
"When true Hair Multiplication comes, it will arise out of the East." - John The Revelator, Feb. 18, 2001


Post reply
rev

your nightmares,
04.03.2012, 07:16

@ Freddie555

It looks like 2014 is the year a hair loss cure hits the market.

I get your point - I truly do, but there's no need to be so dramatic.
Besides, I rather be losing my hair than to be facing down cancer.

I'm in my 30s, and lately I've seen quite a few folks in my age group drop like flies - from stroke, cancer, or work related accidents. Suddenly hairloss doesn't seem quite so bad.

Don't get me wrong, I still want to see a cure(that's why I'm here afterall), but I refuse to obsess over the small details and turn into another spanish-dud, ironsp*m or jarjar/stevie dee/ leroy jenkins/ schizo.


» Consider the number of companies & researchers doing cancer research. Its
» gotta be many thousands and this has been going on since the 1950s. Tons
» of donations & fund raisers pour in every year, tons of big name pharma
» companies researching it, tons of govt money channeled towards it.
»
» Yet there is no cure.
»
» You will however on any given week read news on how a breakthrough in
» cancer research has occured. But still no cure.
»
» Now consider how FEW companies & researchers are doing hair loss research.
» Not a single big name pharma here. Zero govt funding and anemic academic
» research. No global fund raisers or big donors. You can literally count
» them on your hands. I quickly get a sense of how LOW the odds are that we
» will be cured within our lifetimes, nevermind 10 to 15 years.
»
» As if that weren't enough, the FEW researchers who volunteer their time &
» energy towards helping us find a treatment/cure end up being attacked by
» wild monkeys (refer to the Astressin-B Norma trials). That makes the LOW
» odds of finding a cure even lower.
»
» I hate to be a wet blanket but sometimes i feel we are hoping against hope
» here. We are shipwrecked in the middle of the Atlantic ocean and swimming
» in strong current hoping that an island is just over the horizon. The
» reality is the island may well be a 1000 miles away and we will be fish
» food by dawn. No matter what the f&ck we do we are going to drown. The
» only good news is that the monkeys will hopefully drown with us.




rev is located in YOUR NIGHTMARES and he is available to meet: NO

---
Shittin on shills since 08.01.2008.


Post reply
jarjarbinx

04.03.2012, 11:14

@ rev

It looks like 2014 is the year a hair loss cure hits the market.

» I get your point - I truly do, but there's no need to be so dramatic.
» Besides, I rather be losing my hair than to be facing down cancer.
»
» I'm in my 30s, and lately I've seen quite a few folks in my age group drop
» like flies - from stroke, cancer, or work related accidents. Suddenly
» hairloss doesn't seem quite so bad.
»
» Don't get me wrong, I still want to see a cure(that's why I'm here
» afterall), but I refuse to obsess over the small details and turn into
» another spanish-dud, ironsp*m or jarjar/stevie dee/ leroy jenkins/ schizo.



What makes you think you aren't already worse than any of those posters you mentioned? You are definitely worse. You are definitely worse.

To hear you tell it, taking into account all the facts/details is a bad thing. Spoken like the true peanut-gallery, stupid, ignorant chimp that you are. Only a total moron doesn't get it that the details are key. I'm glad you're not like me too. If you and I were alike that would mean that I'm a dumbass.




jarjarbinx is located in [NA] and he is available to meet: NO


Post reply
gutted2

04.03.2012, 12:11

@ Freddie555

It looks like 2014 is the year a hair loss cure hits the market.

» Consider the number of companies & researchers doing cancer research. Its
» gotta be many thousands and this has been going on since the 1950s. Tons
» of donations & fund raisers pour in every year, tons of big name pharma
» companies researching it, tons of govt money channeled towards it.
»
» Yet there is no cure.
»
» You will however on any given week read news on how a breakthrough in
» cancer research has occured. But still no cure.
»
» Now consider how FEW companies & researchers are doing hair loss research.
» Not a single big name pharma here. Zero govt funding and anemic academic
» research. No global fund raisers or big donors. You can literally count
» them on your hands. I quickly get a sense of how LOW the odds are that we
» will be cured within our lifetimes, nevermind 10 to 15 years.
»
» As if that weren't enough, the FEW researchers who volunteer their time &
» energy towards helping us find a treatment/cure end up being attacked by
» wild monkeys (refer to the Astressin-B Norma trials). That makes the LOW
» odds of finding a cure even lower.
»
» I hate to be a wet blanket but sometimes i feel we are hoping against hope
» here. We are shipwrecked in the middle of the Atlantic ocean and swimming
» in strong current hoping that an island is just over the horizon. The
» reality is the island may well be a 1000 miles away and we will be fish
» food by dawn. No matter what the f&ck we do we are going to drown. The
» only good news is that the monkeys will hopefully drown with us.

there will be no such thing and there is no such thing as a cure for cancer, a cure will only exist in the form of a super treatment.

The UK goverment did invest money into intercytex, but thats about it as far as im aware.




gutted2 is located in [NA] and he is available to meet: NO


Post reply
cal

04.03.2012, 14:22
(edited by cal, 04.03.2012, 14:39)

@ gutted2

It looks like 2014 is the year a hair loss cure hits the market.

The clinical trials system basically amounts to a 10-15-year warning system about what is coming ahead of time.

It does not always agree with what MPB researchers are saying but it has a 40-year track record of complete accuracy.

Ignore its current indications if you want.




cal is located in [NA] and he is available to meet: NO


Post reply
rev

your nightmares,
04.03.2012, 14:49

@ jarjarbinx

It looks like 2014 is the year a hair loss cure hits the market.

posted by jarjarbinx, 04.03.2012, 11:14
What makes you think you aren't already worse than any of those posters you mentioned? You are definitely worse. You are definitely worse.

To hear you tell it, taking into account all the facts/details is a bad thing. Spoken like the true peanut-gallery, stupid, ignorant chimp that you are. Only a total moron doesn't get it that the details are key. I'm glad you're not like me too. If you and I were alike that would mean that I'm a dumbass.


...but you're doing such a great job being a dumbass without anyone's assistance.





» Rev
» I get your point - I truly do, but there's no need to be so dramatic.
» Besides, I rather be losing my hair than to be facing down cancer.
»
» I'm in my 30s, and lately I've seen quite a few folks in my age group drop
» like flies - from stroke, cancer, or work related accidents. Suddenly
» hairloss doesn't seem quite so bad.
»
» Don't get me wrong, I still want to see a cure(that's why I'm here
» afterall), but I refuse to obsess over the small details and turn into
» another spanish-dud, ironsp*m or jarjar/stevie dee/ leroy jenkins/ schizo.




rev is located in YOUR NIGHTMARES and he is available to meet: NO

---
Shittin on shills since 08.01.2008.


Post reply
KO

04.03.2012, 16:12

@ cal

It looks like 2014 is the year a hair loss cure hits the market.

This is true, there were no clinical trials for 2nd Gen MPB treatments 10 years ago, much less in the 60s. Right now we have 4 treatments in the clinical trial process, of which at least 2 are serious and legit (Follica and ARI).

Most startups take 10-15 years to go from startup to drug, and ARI has been around for 10 years now and has a decent amount of institutional knowledge built up.

However, the only thing that matters is if they continue on the clinical trial path, and that will be judged whether any of these treatments starts a Phase 3 trial. That will be THE turning point. Passing a Phase 2 trial is a big deal, and by that point they know if a treatment works. So if P3 starts we can start getting optimistic.




KO is located in [NA] and he is available to meet: NO


Post reply
Iron_Man

04.03.2012, 16:40

@ Freddie555

It looks like 2014 is the year a hair loss cure hits the market.

» Consider the number of companies & researchers doing cancer research. Its
» gotta be many thousands and this has been going on since the 1950s. Tons
» of donations & fund raisers pour in every year, tons of big name pharma
» companies researching it, tons of govt money channeled towards it.

Check out these few pages (just read what you can find in English on page 1-10) ...

http://www.haarweb.nl/forum/showthread.php?t=1931

... and tell me what finally happend concerning the promising hair loss cure (initially) versus a cancer cure (later on).

They still have patents for this type of hair loss cure (what in my opinion could be one) - but they do absolutely nothing.




Iron_Man is located in [NA] and he is available to meet: NO

---
I documented the world’s 1st day-by-day (HST) donor hair regeneration process …


Post reply
2020

04.03.2012, 17:21

@ Iron_Man

It looks like 2014 is the year a hair loss cure hits the market.

WE DON'T NEED A CURE!!!! Some sort of injection that boosts your hair count will work just as well. Oh and btw, cancer TREATMENTS have advanced A LOT during the past 40 years...




2020 is located in [NA] and he is available to meet: NO


Post reply
moawk

Germany,
04.03.2012, 18:09

@ KO

It looks like 2014 is the year a hair loss cure hits the market.

» This is true, there were no clinical trials for 2nd Gen MPB treatments 10
» years ago, much less in the 60s. Right now we have 4 treatments in the
» clinical trial process, of which at least 2 are serious and legit (Follica
» and ARI).
»
» Most startups take 10-15 years to go from startup to drug, and ARI has been
» around for 10 years now and has a decent amount of institutional knowledge
» built up.
»
» However, the only thing that matters is if they continue on the clinical
» trial path, and that will be judged whether any of these treatments starts
» a Phase 3 trial. That will be THE turning point. Passing a Phase 2 trial is
» a big deal, and by that point they know if a treatment works. So if P3
» starts we can start getting optimistic.

to be honest i think a cure will be found 20 years from now or so, by cure i mean curing a chrome bald monkey with hardcore shiny bald plates.

sure these treatments coming up will be beneficial but if you're Norwood 5 and above or heading there in the next 6 years, just learn to live with it. It's the best advice I can give. Some of us just regret having a HT and wish we could have just shaved it.

Just Keeping it real guys.




moawk is located in GERMANY and he is available to meet: NO

---
1. Predicted the failure of replicel, months in advance.
2. Predicted how their stock would rise/drop even with exact numbers.
3. Predicted the wild claims and crazyness that gc83uk's donor regeneration will cause among the HT industry during this summer. Including rassman's opinion, Dr. Woods special patients and Pro hair clinic photos.
4. Predicted Gho will open up a clinic in asia.
5. No prediction on Histogen. Looks promising if they didn't fake results.
6. Predicted the only viable HM technique other than Gho would surface when hairs are: "generated through the appropriate cell populations" -Team Tokyo 2012


[image]
- Moawk

Advice for patients: If you are considering a hair transplant, only consider Gho's HST and nothing else. First HT treatment in the world that offers: zero scarring, small downtime and donor regrowth.
http://www.hasci.com

Advice for Investors in HM: Invest in Team Tokyo.
http://www.tsuji-lab.com/en/research/organ/hair.html
Ditch replicel, aderans. They are done for and have no future.


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