Hair Loss - Question about DSC cells...

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Question about DSC cells... (Hair Regrowth Research & Clinical Trials)

posted by KO, 25.04.2012, 22:59

» You're correct Moawk, Ironman doesn't know. But, we shouldn't be too hard
» on him, there is alot that is unknown.
»
» Control of thrombin signaling through PI3K is a mechanism underlying
» plasticity between hair follicle dermal sheath and papilla cells
» J. Cell Sci. 2008 121:1435-1443
»
» "Overall, this points to a significant level of cell plasticity and
» suggests that change in the differentiation status of DP and DS cells might
» play a physiological role during the hair cycle. However, it is unclear
» whether variation in tissue size, cell renewal and cross-reconstitution of
» DP and DS rely on the presence of common undifferentiated precursors (Lako
» et al., 2002; Jahoda et al., 2003; Fernandes et al., 2004) and/or on the
» transdifferentiation of mature mesenchymal cells. Despite the
» fundamental and the practical interest in understanding how two very
» specialized cell types can regenerate cells of the alternate phenotype,
» nothing is known about the molecular mechanisms or
» factors involved."

Good find...although we should keep in mind both DP and DS cells are essentially fibroblasts, so i think they are not that different.




KO is located in [NA] and he is available to meet: NO

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