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Study: licorice and peppermint decrease alpha five, sebum (Hair Loss Supplements)

posted by Pete2, 16.09.2007, 05:34
(edited by Pete2 on 16.09.2007, 05:50)

http://sciencelinks.jp/j-east/article/200408/000020040804A0230063.php



Activity of herbal extracts on the control of sebum secretion.Accession
number;04A0230063
Title;Activity of herbal extracts on the control of sebum secretion.
Author;UCHIUMI YOICHIRO(Maruzen Pharm. Co., Ltd., JPN) YAMAMOTO
SUSUMU(Maruzen Pharm. Co., Ltd., JPN) MIZUTANI KENJI(Maruzen Pharm. Co.,
Ltd., JPN)
Journal Title;Fragr J

Journal Code:G0987B

ISSN:0288-9803

VOL.32;NO.3;PAGE.53-57(2004)
Figure&Table&Reference;TBL.4, REF.13
Pub. Country;Japan
Language;Japanese
Abstract;Potential activity of herbal extracts on sebum secretion was
studied. Among the herbal extracts tested, polyol-soluble licorice extract
P-U (product name) derived from Glycyrrhiza inflata showed the most potent
testosterone 5 .ALPHA.-reductase inhibition, androgen receptor binding
inhibition and antimicrobial activities, which are closely related to
sebum secretion. In addition to the findings on polyol-soluble licorice
extract P-U, clove extract and peppermint extract showed testosterone 5
.ALPHA.-reductase inhibition, arnica extract and rose fruit extract showed
androgen receptor binding inhibition, alpinia speciosa root extract and
scutellaria root extract showed estrogen receptor agonists, and sophora
root extract showed antimicrobial activity. (author abst.)


I dont believe an androgen blockade topically will have any noticeable results with the substances that have been mentioned ie regrowth. Keep us updated.







This is interesting because its HUMAN sebum secretions and HUMAN alpha
five reductase being inhibited, as well as HUMAN androgen receptors being
blocked.
Ive been using peppermint oil mixed with PURIFIED water topically for a
while now, and am happy with the results after an initial shed a month or
so into it. I tested peppermint oil/purified water on one half of my chin
for a few months, and it reduced beard hair pretty impressively compared
with the other side. Peppermint oil is very cheap, and costs about four
bucks an ounce. One ounce mixed with fifty or so ounces of purified water
should last a good year.

Some of the other herbals mentioned in this article like arnica root (a
type of sunflower) and rose fruit (rose hips oil) can also be had very
cheaply. Licorice might have a strong smell, but it was the most
anti-androgenic of the lot.


I became interested in mints as anti-androgens after reading about the
spearmint tea hirsutism study from Turkey, and the men who complained of
no libidio or low libidio after drinking peppermint tea, and the
anti-androgenic effects of peppermint on lab rats. Ive noted that
peppermint extract or peppermint oil is in the following shampoos: Paul
Mitchel LemonSage Thickeing, Paul Mitchell Tea Tree, American Crew
Thickeing (in the form of mint leaves), Jasons Tea Tree, Tricomin Shampoo,
Tricomin Conditioner, its in one of HairCycle's products, and various
"menthols" (which can be and often are synthetics) are in other shampoos
also.


Menthol increases bloodflow and may help to stimulate the scalp.
However you dont want to over stimualte the scalp and make inflammation worse( unless you are using a Dual shampoo to lower inflammation and increase bloodflow). The key is to "drive down" inflammation first topically and then to improve the health/condition of the scalp before stimulating bloodflow (alone).




I think it might be an effective ADDITION to taking our finasteride or
dutasteride. I would not risk going off a proven treatment however, but
think this would/should be quite helpful. I'd love to see further testing
for alopecia, but realize that probably wont ever happen.

If you google "peppermint and hair removal" or "licorice and hair removal"
or "rose hips and hair removal" you will see that many compaines are
obviously aware of the anti-androgenic properties of these substances.


My current regimine...........finasteride, peppermint oil/purified water
mix, prox-n, I use nizoral a couple of times a week also.





Hope someone else can be helped by this for all my pals in the HM forum.






Regards
Pete




Pete2 is located in [NA] and he is available to meet: NO


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