Hair Loss - Vellus hairs and Donora area hairs equal when transplanted to mice
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Vellus hairs and Donora area hairs equal when transplanted to mice (Hair Loss Research & Clinical Trials)

posted by benji, 23.03.2008, 02:47

»
» for one thing i do not recommend niz shampoo, it has hydrochloric acid in
» it, as well as the chemical for embalming fluid, neither of which are in
» the nizoral cream. the shampoo is way too harsh, and only stays on your
» head for about a minute,
» I had way more success with the cream

THERE ARE THREE INDEPENDENT STUDIES SHOWING NIZORAL SHAMPOO INCREASES HAIR COUNT, HAIR SIZE IN CIRCUMFERENCE, AND HAIR WEIGHT WHILE REDUCING SEBUM SECRETIONS, AND EVEN SEBACEOUS GLAND SIZE (19.4%) AT SIX MONTHS--DESPITE ANYTHING ELSE THAT MIGHT BE IN THE SHAMPOO»

» if you can find a dht 5 ar inhibitor that works on you, such as fin, it
» helps a lot but for some reason it stops working after a few years,
» perhaps the body develops an immunity to it
FINASTERIDE NEVER "STOPS WORKING", IT CHEMICALLY BINDS WITH THE FIVE ALPHA REDUCTASE TYPE TWO ENZYMES IN THE VARIOUS LOCATIONS IN THE BODY THAT IT CAN BE FOUND---BUT SINCE DHT IS 'BOUND' BY GLOBULIN IN THE BLOOD STREAM ABOUT 98% OF THE TIME, THE ALPHA FIVE IN QUESTION IS THE TYPE 2 ENZYME THAT IS LOCATED IN THE INNERMOST PORTION OF THE HAIR FOLLICLE'S OUTER ROOT SHEATH THAT ALMOST ASSUREDLY DOES MOST OF THE DAMAGE IN ANDROGENIC ALOPECIA. FINASTERIDE INHIBITS ROUGHLY 85% OF TYPE TWO ALPHA FIVE REDUCTASE ACTIVITY, AND THEREFORE DOESN'T INHIBIT ALL DHT FROM BEING MADE.......ONE STILL HAS ABOUT 15% OF IT. DR. MARTY SAWAYA NOTED AN ANDROGEN RECEPTOR UPREGULATION IN USERS OF FINASTERDIE, BUT ANY KIND OF ANTI-ANDROGEN MIGHT PRODUCE THIS EFFECT. HER RESULTS HAVE, HOWEVER, NEVER BEEN DUPLICATED


»
» I also think that it depends on if you are thinning or bald in that area,
» also for how long you have been thinning, Thinnng hair has , in my opinion
» about 1000 times more chance of coming back to life than bald areas. I
» think that hair in slick bald areas is next to impossible to revive
»
» I liken it, to leaving for vacation you come back your yard is brown from
» lack of water, you can water the grass and it comes back to
» life........thats thinning hair
»
» If you leave for 2 yrs you come back there is dirt there instead of grass,
» good luck watering it and having it come back to life. the grass is dead.
» To me this is the same with slick bald scalp
»
» nothing i have ever tried has gotten my slick bald spot in the crown back,
» whereas my DHT blockers have totally reversed my thinning hair to where it
» is semi normal no longer see through, and about 4 times as thick as it was
» before i started all my dht blockers

IF YOU LOOK CLOSE AT YOUR 'SLICK' BALD AREA, VERY VERY CLOSE, YOU WILL NOTE THAT IT WILL BE COVERED IN VELLUS HAIRS. GUESS WHAT???? THESE USED TO BE YOUR FULL-SIZED FOLLICES YEARS AGO. THEY DONT DIE. THEY CAN BE 'SCARRED UP' AND SURROUNDED IN COLLAGEN---BUT THIS STUDY SHOWS THAT IF THEY ARE TRANSPLANTED TO IMMUNODEFICIENT MICE THAT THEY CAN RE-ENLARGE JUST LIKE OTHER HAIRS TRANSPLANTED FROM THE DONOR AREA.


Its been pointed out in research that balding hairs lose a molecule........CD200 that tells the immune system not to attack a particular organ. This might be what causes the immune system to never stop suppressing balding hairs, for once this molecule is lost.............it keeps inflaming the follicle at the uppper portion near the infidulum, and possibly keeping the arrector pilli muscle from being able to supply the necessary stem cells to the papilla to initiate a new anagen phase--------keeping it small forever.



The question is what prostaglandin, peptide, cytokine, whatever keeps telling the body not to put CD200 back at the follicle site. Why doesnt the follicle become immuno-priveleged again after one gets on dutasteride (stops 98% of type two alpha five and 52% of type one). There has got to be some other substance stopping the hairs from re-enlarging----or castrates would grow back ALL their hair. Anybody have any EDUCATED guesses or ideas
»
» if you are not on a super hair vitamin you should try it, makes a huge
» difference---- its probably pretty good. It has lysine, arginine, the same amino acids that are in the triamino polypeptide formula of tricomin and a few other hair-healthy nutrients like biotin, msm, silica, manganese...........but I take a very good multivatimin packet that has alot of this stuff in it plus fish oil and saw palmetto are also in my vitamin. I figure its pretty "decent" in the healthy hair department. Ive been stuck at the same place for about five years...........no more hair or less.


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