Hair Loss - Let's focus on the FUNDAMENTALS, not the little details

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Let's focus on the FUNDAMENTALS, not the little details (Topicals)

posted by haroldo, 16.04.2008, 03:59

ť ť OK just wrote and lost a large reply...
ť
ť Sounds like you took so long that the "posting timer" timed-out on you,
ť and you lost everythign you had written! That's a PISSER when that
ť happens, isn't it?? :angry:

Oh man I thought that must have been what happened - it asked me to login again. Yeah that was super annoying.

ť David (hairsite admin)!! Get this problem fixed once and for all!!!
ť
ť ť ...but basically - those various factors
ť ť you are talking about are in themselves the fundamental difference that
ť you
ť ť are looking for. One may prove to be upstream of the others or more
ť ť important but there is no reason for scalp hairs to behave differently
ť to
ť ť body hairs beyond the fact that they are different cell types and thus
ť ť express different genes just as skin cells and muscle cells do. On the
ť ť other hand all may be equally important or some may only play a part in
ť ť balding white men, others in Asian men etc. But at the end of the day
ť ť theres no reason behind it other than the reality of which genes get
ť ť transcribed when the androgen binds to the androgen receptor and
ť travels
ť ť into the nucleus.
ť
ť I'm not entirely sure what your overall point is. I don't really disagree
ť with anything you said.

I guess from your earlier post it seemed like you felt the study of and worrying about stuff like TGF-Beta etc was not important because there was a fundamental difference that would explain WHY scalp hairs produced growth inhibitors when exposed to DHT and why beard hairs produced growth promoters. Whereas I was trying to say that there is no reason behind the difference - it just is. Maybe I misunderstood you in that you were saying that it is a waste of our time now to worry about it when we still dont know exactly how much of a role each of these new factors plays in the balding process and what needs to be done to stop them but it sounded like you wanted to know why they were produced at all.
At any rate I do think that whole alphabet soup stuff is really important and exciting and that is where any breakthrough in understanding and treatment effectiveness is going to come from in this whole thing. If every study since the first TGF-Beta/IGF had reported the same central importance of TGF-Beta 1 I would be betting the hair on trying to find some topical to inhibit TGF-Beta 1 activity right now.
hh

haroldo is located in [NA] and he is available to meet: NO

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Complete thread:

My "theory" of baldness..................... - benji, 08.04.2008, 20:33 (Topicals)
- My "theory" of baldness..................... - Goingallout, 09.04.2008, 00:20
  - My "theory" of baldness..................... - benji, 09.04.2008, 00:46
- My "theory" of baldness..................... - Bryan, 09.04.2008, 03:59
  - My "theory" of baldness..................... - benji, 09.04.2008, 20:21
    - Let's focus on the FUNDAMENTALS, not the little details - Bryan, 09.04.2008, 21:41
      - Let's focus on the FUNDAMENTALS, not the little details - goata007, 09.04.2008, 21:52
        Let's focus on the FUNDAMENTALS, not the little details - Bryan, 09.04.2008, 22:14
        Let's focus on the FUNDAMENTALS, not the little details - benji, 09.04.2008, 22:27
        Let's focus on the FUNDAMENTALS, not the little details - goata007, 10.04.2008, 18:40
        Let's focus on the FUNDAMENTALS, not the little details - Bryan, 10.04.2008, 21:03
        Let's focus on the FUNDAMENTALS, not the little details - goata007, 13.04.2008, 16:56
        for Goata - benji, 10.04.2008, 21:46
      - Let's focus on the FUNDAMENTALS, not the little details - haroldo, 15.04.2008, 01:45
        Let's focus on the FUNDAMENTALS, not the little details - Bryan, 15.04.2008, 15:35
        Let's focus on the FUNDAMENTALS, not the little details - haroldo, 16.04.2008, 03:59
        Let's focus on the FUNDAMENTALS, not the little details - Bryan, 16.04.2008, 05:44
        Let's focus on the FUNDAMENTALS, not the little details - haroldo, 16.04.2008, 14:42
        Let's focus on the FUNDAMENTALS, not the little details - Bryan, 16.04.2008, 22:25
        Let's focus on the FUNDAMENTALS, not the little details - benji, 16.04.2008, 22:56
        Let's focus on the FUNDAMENTALS, not the little details - Bryan, 16.04.2008, 23:16
        Let's focus on the FUNDAMENTALS, not the little details - haroldo, 17.04.2008, 05:37
        Let's focus on the FUNDAMENTALS, not the little details - Bryan, 17.04.2008, 22:46
        Let's focus on the FUNDAMENTALS, not the little details - Bryan, 17.04.2008, 23:02
        Let's focus on the FUNDAMENTALS, not the little details - benji, 18.04.2008, 01:07
        Let's focus on the FUNDAMENTALS, not the little details - haroldo, 18.04.2008, 10:32
        Let's focus on the FUNDAMENTALS, not the little details - Bryan, 19.04.2008, 16:36
        Let's focus on the FUNDAMENTALS, not the little details - Bryan, 19.04.2008, 17:39
        Let's focus on the FUNDAMENTALS, not the little details - haroldo, 21.04.2008, 02:19
      - Let's focus on the FUNDAMENTALS, not the little details - JamesJ, 03.06.2008, 00:13
        Let's focus on the FUNDAMENTALS, not the little details - Ignatius, 01.07.2008, 05:03
        Let's focus on the FUNDAMENTALS, not the little details - Bryan, 02.07.2008, 12:18
        Let's focus on the FUNDAMENTALS, not the little details - Bryan, 02.07.2008, 12:29
        Let's focus on the FUNDAMENTALS, not the little details - JamesJ, 05.07.2008, 19:14
        Let's focus on the FUNDAMENTALS, not the little details - Bryan, 05.07.2008, 19:47
        Let's focus on the FUNDAMENTALS, not the little details - JamesJ, 09.07.2008, 22:47
        Let's focus on the FUNDAMENTALS, not the little details - Bryan, 10.07.2008, 04:09
  - My "theory" of baldness..................... - UWbio, 10.07.2008, 17:28
    - My "theory" of baldness..................... - benji, 10.07.2008, 21:34
- My "theory" of baldness..................... - HanginInThere, 09.04.2008, 07:09
- The genetics of MPB - TAGOHL, 09.04.2008, 10:50
  - TAGHL, Ectodysplasin and wreath shape?? (study) - benji, 09.04.2008, 19:59
    - TAGOHL, .....Ectodysplasin and "skin, hair, nails, teeth, sweat glands" - benji, 09.04.2008, 20:34
      - TAGOHL, ..... - TAGOHL, 09.04.2008, 23:37
        TAGOHL, ..... - Jtelecom, 10.04.2008, 19:19
        TAGOHL, ..... - TAGOHL, 11.04.2008, 10:42
        TAGOHL, ..... - TAGOHL, 11.04.2008, 10:43
        TAGOHL, ..... - Bryan, 11.04.2008, 19:42
        TAGOHL, ..... - Jtelecom, 11.04.2008, 18:36
        TAGOHL, ..... (Follica and new genetic information) - benji, 10.04.2008, 21:27
        TAGOHL, ..... (Follica and new genetic information) - Bryan, 11.04.2008, 19:46
        TAGOHL, ..... (Follica and new genetic information) - HanginInThere, 01.07.2008, 14:32