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follow up question (Topicals)

posted by HairSite Admin , 01.05.2008, 07:25

Present evidence suggests that minoxidil acts mainly on the hair cycle; it may also increase hair diameter ...............................
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The results of histological studies in humans are less conclusive than in the macaque. Abell[10] found a trend towards an increase in anagen/telogen ratios after 12 months of minoxidil treatment in balding men, but the main change was an increase in mean hair diameter. This was most apparent at 4 months and mean diameter had declined at 12 months. He suggested this might be due to later recruitment of small diameter hairs into anagen. Headington and Novak[11] reported that minoxidil treatment caused hypertrophy of follicles but, although there was an increase in mean hair diameter in minoxidil-treated balding men after 12 weeks, a similar increase occurred in control subjects......................................................
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This does not necessarily imply that individual hair follicles become larger, as an increase in mean diameter may also occur through preferential recruitment of large diameter hairs in a latent phase of the hair cycle.

http://www.medscape.com/viewarticle/470297_2


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