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Nizoral Shampoo (Topicals)

posted by HairSite Admin , 06.05.2008, 08:39

Med Hypotheses. 2004;62(1):112-5

Ketocazole as an adjunct to finasteride in the treatment of androgenetic alopecia in men.

Dihydrotestosterone (DHT) binding to androgen receptors (AR) in hair follicles is commonly accepted as the first step leading to the miniaturizing of follicles associated with androgenetic alopecia (AGA).

Testosterone is converted to DHT by the enzyme 5alpha-reductase. Finasateride a 5alpha-reducase inhibitor blocks the production of DHT and is currently used to treat AGA. The inhibition is not complete but a reduction of DHT systemically and in the scalp is accomplished. Ketoconazole has been clinically shown to be effective in the treatment of AGA.

In this paper, evidence is presented to support the hypothesis that ketoconazole 2% shampoo has a local disruption of the DHT pathway. It is proposed that using ketoconazole 2% shampoo as an adjunct to finasteride treatment could lead to a more complete inhibition of DHT and thus better treat AGA.







» What do you people think about the effectiveness of adding 1% or 2% Nizoral
» Shampoo to Propacia?
» (not for hair growth, but for the halting or the reduction of hair loss)


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Complete thread:

• Nizoral Shampoo - Wiskers, 06.05.2008, 02:55 (Topicals)
  • Nizoral Shampoo - HanginInThere, 06.05.2008, 06:01
    • Nizoral Shampoo - louis9, 09.05.2008, 20:28
  • Nizoral Shampoo - HairSite Admin, 06.05.2008, 08:35
  • Nizoral Shampoo - HairSite Admin, 06.05.2008, 08:39
    • The shampoo is too harsh, use the cream - HanginInThere, 06.05.2008, 08:46
      • The shampoo is too harsh, use the cream - rev, 06.05.2008, 17:12
        • The shampoo is too harsh, use the cream - HanginInThere, 07.05.2008, 04:35
          • The shampoo is too harsh, use the cream - rev, 07.05.2008, 05:19
            • The shampoo is too harsh, use the cream - HanginInThere, 07.05.2008, 06:11
              • The shampoo is too harsh, use the cream - rev, 07.05.2008, 06:14
                • The shampoo is too harsh, use the cream - HanginInThere, 07.05.2008, 13:37
                  • The shampoo is too harsh, use the cream - rev, 07.05.2008, 17:57
  • Nizoral Shampoo - checkingin, 08.05.2008, 10:16
  • PTO Shampoo - Pete2, 08.05.2008, 13:34