Hair Loss - Robotic Expansion of Cells for Use in Tissue

IHTI Newsletter, Summer 2008 - The Cole Hair Transplant Group
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Robotic Expansion of Cells for Use in Tissue (Hair Multiplication & Research)

posted by HanginInThere, 07.05.2008, 04:40

ť just quickly skimming through the document, I found some stuff from Dr
ť Kemp
ť
ť Page 113
ť Robotic Expansion of Cells for Use in Tissue
ť Engineering of Hair
ť Kemp, Paul D.; Intercytex, Manchester, UK
ť In order for hair multiplication by follicular cell implantation to be a
ť practical proposition, the number of cells returned to the patient must be
ť significantly greater than the number harvested. Moreover, for this process
ť to be commercially successful and cover the high costs of cell culture,
ť amanufacturing facility must have the capacity to expand the cells of many
ť patients simultaneously. For safety reasons, each culture must be
ť maintained in total isolation from the others to ensure that no
ť cross-contamination can occur between the various patients cells. This has
ť been a long standing issue with organisations involved in tissue
ť engineering, especially those involved in autologous therapies. Three basic
ť approaches have been employed to deal with the issues, and all three will
ť be presented and their advantages and disadvantages discussed. Intercytex
ť is following a strategy based on a robotic cell culture system that was
ť previously developed and proven in the area of high throughput screening.
ť This system uses standard tissue culture vessels and dispensers to feed and
ť passage mammalian cells although they are net yet approved by regulators
ť for use in tissue engineering. The adoption of a robotic system will impact
ť research decisions made early in the development of a cell culture process
ť so that the process will be made robot friendly. The system will be
ť presented and the route to regulatory approval discussed.
ť
ť
ť Large Scale Manufacturing of Cell Therapy
ť For Hair Regeneration
ť Kemp, Paul D.; Intercytex, Manchester, UK
ť The implantation of follicular cells, expanded in culture, to induce
ť potentially unlimited amounts of hair has been suggested ever since the
ť work of Oliver and Jahoda. Companies are currently in Phase I and II
ť studies to test preparations of cells for hair induction. It seems from the
ť long history of research in this area that processes will soon be developed
ť to successfully achieve this long sought after treatment. But how will
ť these processes be translated into an industry whereby thousands or
ť hundreds of thousands of people could be treated annually? Tissue
ť Engineering is an industry now in its third decade and over a quarter of a
ť million people have been treated by a variety of cultured cell constructs.
ť The early pioneers developed processes often by trial and error, and only
ť now is best practise beginning to emerge. The lessons learned in the past
ť are crucial to the current development of tissue engineered hair and are
ť the subject of this presentation. All tissue engineering processes can be
ť broken down into six stages: Tissue Procurement; Cell Isolation; Cell
ť Expansion; Assembly; Shipping; and Application. Regulations,
ť industry standards, and developments in other fields are rapidly evolving
ť and influencing each of these stages. The talk will cover these six stages
ť and describe how an industrial process could be developed to meet the
ť commercial needs of large scale follicular cell implantation.

excellent cut and paste

---
Hangin Regimen...........

Maxi Hair by Country Life 2/day
Kal Amino Max ..Chelated Multi Mineral..2/day

DHT blockers (daily intake)
Saw Palmetto, 320mg Standardized
Pygeum 500mg
Nettles 500mg
Beta Sitosterol 125mg
2% Nizoral Cream Topically Nightly,,,after Shampoo

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Complete thread:

Fifth International Congress of Hair Research - rev, 07.05.2008, 02:05 (Hair Multiplication & Research)
- Fifth International Congress of Hair Research - Arch Koven, 07.05.2008, 03:46
  - Fifth International Congress of Hair Research - rev, 07.05.2008, 03:49
    - Fifth International Congress of Hair Research - HanginInThere, 07.05.2008, 04:40
  - Fifth International Congress of Hair Research - MPB, 07.05.2008, 07:37
  - Fifth International Congress of Hair Research - benji, 07.05.2008, 13:13
- Robotic Expansion of Cells for Use in Tissue - rev, 07.05.2008, 04:26
  - Robotic Expansion of Cells for Use in Tissue - HanginInThere, 07.05.2008, 04:40
- Proto-Hair Development In Vitro - rev, 07.05.2008, 05:07
- So What's Ken Washenik up to... - rev, 07.05.2008, 05:13
  - this is great... - SPQR, 07.05.2008, 12:14
    - this is great... - benji, 07.05.2008, 13:23
      - this is great... - SPQR, 07.05.2008, 16:17
      - this is great... - AJ, 07.05.2008, 16:25

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