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 Dr. Klein Hair Regrowth Formula - clinically proven    

Limitless Donor Supply-Acell (Hair Transplant)

posted by benji, 03.06.2007, 23:26

Raptor,

While Im very impressed with the photogrpahs in the picture that shows dog fur in injured areas growing all the way back, there is a concern with this product in regards to efficacy for MPB.

That concern is that these animals do not have male pattern baldness. Dogs dont go bald naturally in response to testosterone like we do.

The recent Costarialis announcement that in response to wound healing, if wnt pathways can be upregulated, hair can regrow face much the same problem. Namely, we can get the miniaturized hairs to regrow, but for how long? Now the MPB hairs are growing again, and they are now producing larger dermal papillas that have many more receptor sites to be hit by .............much more DHT. Unless the underlying genetics of the hairs in MPB are changed, how long would they last?

Thats a conundrum. I'd love to see it tested though. Im for anything that will give men full heads of hair.


I could show you pictures of various topicals for instance that grow hair like wildfire on shaved mice. Minxodil will do this vs. placebo, grape seed proanthoscyandins will do it, barley proanthocyandins will do it, apple proanthocyandins will do it, copper peptides will do it, latanaprost will do it, phenytoin will do it, etc. There are abundant hypertrichotics out there, but counteracting the hormonal shutdown of hair in androgenic alopecia as a result of male hormone being uptaken at androgen receptors, too much TGF beta,TGF beta 2, thrombospondin, FGF-5, IL-1, and PKC being made by the dermal papilla and sent to other cells in the follicle, slowing their growth, and somehow inviting an immune response that sees the dermal fibroblasts around the hair follicle deposit to much collagen underneath the follicle and in the root sheath, surrounding it, and superoxides and inflammatory cytokines sent at the follicle scarring its structure and resulting in the apoptosis (cellular death) in some important follicle parts, are the etiology of the genetic condition we call male pattern baldness. I wonder if something like Acell could be used to get hairs growing so treatments like finasteride, spiro and minox could keep them "alive" however.


Like I said, I'd love to see it tested in human beings, but like lots of guys at hairsite, who have had our hopes raised before...............we are kinda world weary when it comes to anything that doesn't simply multiply the donor area for re-implantation.


Youre quite right about tranpslants,,,,,,,,,,,,,,,they would be wonderful if the docs could simply "make" about 40,000 more hairs to put it.


benji is located in [NA] and he is available to meet: NO

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