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benji (Hair Multiplication & Research)

posted by benji, 05.07.2008, 17:38

http://www.wipo.int/pctdb/en/fetch.jsp?SEARCH_IA=US2007020842&DBSELECT=PCT&C=10&TOTAL=5&IDB=0&TYPE_FIELD=256&SERVER_TYPE=19-10&QUERY=%28FP%2Fcotsarelis%29+&START=1&ELEMENT_SET=B&SORT=41240713-KEY&RESULT=1&DISP=25&FORM=SEP-0%2FHITNUM%2CB-ENG%2CDP%2CMC%2CAN%2CPA%2CABSUM-ENG&IDOC=1408926&IA=US2007020842&LANG=ENG&DISPLAY=DESC



Thats the follica kit patent. I suggest you read it. Lithium Chloride and wnt aren't even mentioned in this patent. They have probably found out that although these increase the amount and size of hairs, that they aren't necessary to grow it on human skin.............




http://www.wipo.int/pctdb/en/wo.jsp?wo=2006105109&IA=WO2006105109&DISPLAY=DESC

that is the older follica patent, it has info about the usage of wnt7a or substitutes that can mimic it.





in the most basic expermient, they wounded human skin grafted onto a SCID mouse..............and seven days later hair germs were detected in wounded skin with no adjuvants needed. They have found that by blocking epidermal growth factor with drugs like getfitinib, that more (and probably larger) hair follicles form. They have also found that usage of minoxidil and finasteride or other anti-androgens, aid the environment in the abraded skin surface area to be more condusive to better results insosfar as new hair is concerned. They have also found that three days before abrading the skin, that plucking the hairs present in the area will put all of them in a new anagen phase at the time of the abrasion, and the growth signalls radiated off the anagen hairs seems to help the process make more new hair also.
Basically it looks like this...........depilate, wait three days, abrade, start the finasteride, wait three to five days (or at least until the skin re-epilithializes after the abrasion), then take the egf-inhbitor, and the minoxidil for several days (but less than ten days).................other things in the patent apparently help more hairs form, but in the most basic copyrighted form of the patent these three things (finas, egf-blocker, minox) are all they use after the abrasion. If it makes new hairs, I'd strongly recommend staying on the finasteride because they are made in mpb areas from the same stem cell lines..........



You really need to read through both of the patents though............



Example 7 in the patent is the one to focus on because it grew human hair on human skin.


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