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Great news! (Hair Multiplication & Research)

posted by Striver, 21.07.2008, 20:48

» The word "HARVARD" should mean a lot to all of you.
»
»
» That means this trial is serious business and the company is certainly no
» joke.
»
»
» Only treating a small bald spot w/out any other adjuvants is a great way
» to see what pathways are activated in vivo with a human being in response
» to abrasion and if hair follicle placodes, cells, proto hairs start
» development without any chemical help at all.
»
»
» Remember in Experiment 7 of the Patent, the one they were able to
» replicate, they simply abraded human skin grafted to a SCID mouse and were
» able to get hair germs by day 7. That was donor area skin though, obtained
» from strip-scar hair transplant clinics that would have been thrown away.
» This is bald MPB scalp----that sometimes has some micro-scarring from
» micro-inflammation due to the MPB immunological events over many years.
»
»
» If they find pathway x or y is initiated in vivo in response to abrasion,
» CO2 lasers, soundwaves, chemical peels or whatever, they might be able to
» take away some of the adjuvants they feel are necessary to coax the
» epidermal stem cells to build new follicles------or they may find they need
» to add some other stimulatory compounds (fiberblast growth factor or
» topical beta catenin or whatever). This will be an excellent way to
» determine what exactly happens in the skin of live people in response to
» abrasion in MPB-scalp.
»
»
» The fact that this is being done at Harvard after being researched at Penn
» should be very encouraging to everyone here.
»
»
»
»
»
» BTW-------There are no 'magic compounds'. If you read the patent, Follica
» tells you EXACTLY what they are considering using as adjuvants in a topical
» forumulation......EGF-antagonists, potassium channel openiers, Nitric Oxide
» agonists, retinoids, perhpaps immunosuppressants (they will no doubt be
» looking for particular immuno markers in skin in response to the wounding),
» anti-microbials, and anti-inflammatories, and possibly fiberblast growth
» factors like FGF7, and maybe beta catenin and wnt-protiens or wnt-mimetics
» like LiCl.
» These experiments are a great way to see if some of those can be shed or
» another thing or two has to be added for EDIHN hairs to grow on MPB scalp
» as opposed to donor-area scalp etc.
»
»
» The ball is rolling though.............................We had to wait
» three years for ICX to go from phase one to phase two while rolling our
» fingers.

I think one of the doctors in their team is at Harvard.


Striver is located in [NA] and he is available to meet: NO


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