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 Dr. Klein Hair Regrowth Formula - clinically proven    

to benji (All Topicals & Shampoos)

posted by benji, 12.08.2008, 22:07

» i have an oily saclp since last year
» so are these gel caps proven to work or u just read sth about it


"To elucidate the biological activity in vivo, the isoflavone and genistein were systemically applied to fuzzy rat(conc: 0mg, 50mg, 100mg, 200mg /body weight). The secreted sebum and the size of sebaceous glands of fuzzy rat were measured after 6 weeks.
Isoflavone showed higher inhibition activity of 5a-reductase type 2 ( IC50 value=2.4µ¶/µ˘) than that of isoflavone, but lower than that of finasteride. The amount of sebum and sebaceous gland size decreased remarkably in in-vivo test using fuzzy rat model
We have demonstrated the inhibitory activity of isoflavone and genistein for 5a-reductase type 2 and its biological action in fuzzy rat models, suggesting that genistein and isoflavone would be used as an effective agent for androgenetic acne and for the inhibition of secretion of sebum by modifying androgen conversion. "





That was the info given in the study.



Now here is the problem. Genistein inhibits epidermal growth factor. New information seems to indicate the for resting hairs to go into anagen, there has to be some epidermal growth factor signalling. Green tea's EGCG pretty much does the same thing.




One thing that has been shown to decrease sebum greatly after a few weeks on human skin is cedarwood oil. Fluridil should decrease sebum somewhat. Dutasteride probably does to a lesser degree. Nizoral shrank sebacous glands when used 2-4 times per week by about 20% and lessened sebum secretions during that time also. Thats about all I know.


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