Hair Loss - tamoxifen vs Arimidex (Anastrozole); E in general

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tamoxifen vs Arimidex (Anastrozole); E in general (Propecia, Avodart, Spiro, DHT & hormones ...)

posted by gc1961, 20.06.2007, 08:13

» » Maybe you had counterfeit Arimidex; there is a ton of research on its
» » effectiveness on inhibiting E. I doubt you could take it and not see a
» » result unless you were taking fake meds; I work in the industry and
» » outside the US >20% of meds are fake - especially branded, high-priced
» » meds like Arimidex.
» »
» » As for more DHT as a result of taking Arimidex, I have not seen
» research
» » that suggests this. Have you? Without such research I can just as
» easily
» » speculate that HPTA feedback would maintain the T level; BTW the amount
» of
» » E relative to T is 1/100th, so you would only be increasing T by 1% by
» » completely blockading E production. Further, it is very clear that a
» » complete blockade on T-to-DHT does not prevent hairloss in the majority
» of
» » people. There are many more factors to hairloss (or prostate cancer)
» than
» » DHT; much of the new research points to E.
» »
» » Regarding SHBG, there are many question marks around your point.
» Firstly
» » >50% of T at the hair folicle is generated at the follicle; either from
» » cholesterol or from Adrenal DHEA. This is not transported via SHBG or
» » Albumin binding. Secondly, hormones that are bound by SHBG can and do
» » dissociate and there are suggestions that SHBG-bound-DHT might be
» active
» » in binding to the follicle (the SHBG aligns the DHT in one theory); so
» the
» » classical view of bioactive T is very questionable for sites that
» express
» » the 450 class enymes as hair does).
» »
» » No one knows the answers.
»
» I had the astra zeneca thing... Tested my E2 before taking it:17pg/ml if
» I remember, and two months later: 17pg/ml (same lab)...
» I'm on 2.5mg finasteride daily and know that the ideal dosage would be 4mg
» (I tested it) to retain my hair. Problem is: libido is weak at 2.5, so
» what would it be at 4, long term? What's your own dosage of finasteride
» currently? What would you advise me? You seem to be very knowledgeable.

Like you, I take 2.5mg; 1/4 generic proscar in the morning 1/4 in the evening. I think Bryan could and would point to research showing little serum DHT reduction from 1.25mg to 2.5mg.

I am not sure going to 4mg will make a difference.

Re the libido thing, I never had a problem with it; while I suspect this is just a difference in the hormone balance in certain individuals, I have also been continuously supplementing with NO2 (Nitric Oxide) from GNC. NO is a vasodilator and may help with the libido. I also believe that NO2 (or other Arginine supplements) is very supportive in fighting hair-loss.


gc1961 is located in [NA] and he is available to meet: NO

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