Hair Loss - estradiol

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estradiol (Propecia, Avodart, Spiro, DHT & hormones ...)

posted by gc1961, 20.06.2007, 08:24

» gc, what about estradiol? How come some guys use topical that has estradiol
» in it? What is the reason for that?
Like male androgens, there are many hormones classsed as Estrogens; and just like T and DHT, some Estrogens are stronger than others.

Estrogen is currently a hot topic in breast and prostate cancer; in both cases it is viewed negatively. Yet in hairloss discussion the majority of people believe that Estrogen is a benefit, and hence the supplementation.

I do not share this opinion and have read many medical papers that increasingly identify Estrogen as very negative.

A thing to remember here is that a lot of our knowledge here is <10 years old, for example the fact that there are two different Estrogen Receptors (alpha and beta) expressed in human hair. These seem to be in opposition in many of their properties, so the balance of the two may be critical.

The net of the E research I have done suggests that the primary action of E in MPB is that it inhibits new hair from entering anagen (growth) phase.

BTW there are herbal supplements that modify E metabolism significantly, e.g. Indole-3-Carbinol. These promote less active forms of Estrogen and appear as an alternative to toxic cancer drugs like Tamoxifen.

This is a big subject.


gc1961 is located in [NA] and he is available to meet: NO

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