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HAIR MULTIPLICATION & HAIR LOSS RESEARCH

Hair Multiplication Forum - Current

Oct 03 - Oct 09, 2005
Hair Multiplication – InterCytex’s TrichoCyte Trial Invite
TrichoCyte Hair Treatment in an uncontrolled first in human study. Volunteer information sheet.
Click here for details

Sep 12 - Sep 18, 2005
Hair Multiplication – Dr. Bazan Patient’s 105-page Report
BJO detailed account of his experience as a patient of Dr. Bazan.
Click here for details

Aug 29 - Sep 04, 2005
Hair Multiplication – University of Western Sydney, New Player in Hair Multiplication Research ?
Hair follicle neogenesis. We have developed microsurgical procedures to isolate follicle inductive cells and culture methods to increase their numbers in vitro. Grafting of cultured cells to animal recipients have resulted in follicle neogenesis and hair growth. Our research has reached the development stage and have identified a commercial partner. The objective is to use molecular biology, transgenesis and bioreactor technology to launch cell therapies for hair replacement in humans.
Click here for details

Aug 22 - Aug 28, 2005
Hair Multiplication – Isolagen to Face Class Action Lawsuit
The complaint alleges that Isolagen made a series of false or misleading statements concerning the development and commercialization of its autologous cellular therapies and its prospects for FDA approval.
Click here for details

Aug 01 - Aug 07, 2005
Hair Multiplication – Cultured Fibroblast as a Treatment for Hair Loss
Fibroblasts works by stimulating hair protein production using a patient's own cells. The treatment begins with the injection of a local anaesthetic to numb a small section of skin/hair follicles at the back of the head. This area was chosen because of its genetic print and the invisibility of any scarring. After approximately six weeks, 1 to 1.5 ml of cultured fibroblasts are sent back to the doctor for injection into the patient's pate.
Click here for details

Aug 01 - Aug 07, 2005
Hair Multiplication – Isolagen’s Hair Regrowth Treatment
Isolagen’s patent and basic info about their technique as a hair regrowth treatment.
Click here for details

Jul 25 - Jul 31, 2005
Hair Multiplication – Dr. Bernstein Provides a Straight Forward Discussion on Hair Cloning vs Hair Multiplication vs Tissue Engineering.
For those who are new to this forum, you may find this helpful as it talks about Hair Cloning, Hair Multiplication & Genetic Engineering for hair loss.
Click here for details

Jul 18 - Jul 24, 2005
Hair Multiplication – InterCytex’s Multiplication Factor According to the Patent
Forum discussion suggesting that InterCytex may be able to duplicate a full head of hair with just 30 follicles.
Click here for details

Jul 11 - Jul 17, 2005
Hair Multiplication – Dr. Washenik on Aderans Research Institute’s Hair Multiplication Project
Dr. Washenik envisioned a launch on the market somewhere in 2009 and that traditional hair transplant will still have a role to play even when Hair Multiplication becomes available. Also, unlimited follicles may not be possible with first generation Hair Multiplication techniques.
Click here for details

Jul 04 - Jul 10, 2005
Hair Multiplication – Aderans’ year 2003 and year 2005 Annual Report now available online
Preparations to gain FDA approval are proceeding according to plan and commercial availability of Hair Multiplication to be expected in year 2007.
Click here for details

Jun 27 - Jul 03, 2005
Hair Multiplication – Aderans Medium-term Management Plan
Aderans plans to introduce cellular biological treatment for hairloss in calendar year 2007. Fda approval process proceeding according to plan. Will take Bosley public within 3 years. Expansion of Bosley into Canada and Mexico (and elsewhere).
Click here for details

Jun 20 - Jun 26, 2005
Hair Multiplication – Hair Science Institute, Dr. Gho’s latest Endeavor
Dr. Coen Gho announced the formation of Hair Science Institute. Hair Multiplication research will remain the heart and soul of Dr. Gho’s research efforts. The research will be built upon existing knowledge as well as new insights & technologies that have been discovered or invented since the first Hair Multiplication patent was filed in 1997.
Click here for details

Jun 13 - Jun 19, 2005
Hair Multiplication – InterCytex’s Information Sheet on TrichoCyte
Information sheet on InterCytex’s autologous hair regeneration therapy for the treatment of male pattern baldness and female diffuse alopecia.
Click here for details

Jun 13 - Jun 19, 2005
Hair Multiplication – Official Statement from Gho Clinic since its Corporate Restructuring in December 2004.
This is the first public statement on the internet from Gho Clinic since the company filed for bankruptcy in December 2004.
Click here for details

Jun 06 - Jun 12, 2005
Research – Hair Loss Gene Found?
Scientists found that variations in a gene related to male sex hormones may be at the root of male-pattern baldness, the most common form of hair loss. The culprit is the androgen receptor gene, and it dwells on the X chromosome, which all men inherit from their mothers.

Click here for details

Jun 06 - Jun 12, 2005
Hair Multiplication – Aderans Completed Initial Discussion with the FDA
Aderans Research Institute completed initial discussion with the FDA about their Hair Multiplication procedure. "We are very excited at how well our research in hair multiplication has progressed. We are very close to the first time in history when the number of hairs on the scalp can be increased significantly." John Ohanesian
Click here for details

May 30 - Jun 05, 2005
Hair Multiplication – Isolagen’s Autologous Cultured Fibroblasts: A Protein Repair System
In depth technical details about Isolagen’s fibroblast injections treatment.
Click here for details

May 30 - Jun 05, 2005
Hair Multiplication – Aderan Research Institute Patents
Inside look at two of Aderan Research Institute’s hair multiplication related patents.
Click here for details

May 23 - May 29, 2005
Hair Multiplication – Wall Street Journal article on Hair Cloning
Hair Multiplication – Wall Street Journal article on Hair Cloning As suggested by the Wall Street Journal, the initial cost for Aderans hair multiplication procedure will be about $8,000 - $12,000 to be offered in addition to a traditional hair transplant.
Click here for details

May 02 - May 08, 2005
Hair Multiplication – Curis’ New Treatment for Hair Loss Using Hedgehog Signaling.
”Hedgehog is one of many cell-signaling pathways that scientists are scrutinizing. And Curis hopes it will work wonders on thinning pates of both males and females. When you see a lustrous head of hair, chances are it's at least partly due to healthy Hedgehog signaling, which prompts the body's multitalented stem cells to proliferate around follicles, initiating hair growth. By activating Hedgehog, Curis' drug targets hair growth at its root, so to speak. That could make the drug more effective than current treatments, which mainly aim to increase the size of shrunken hair follicles or to fight certain hormones involved in hair loss.”
Click here for details

May 02 - May 08, 2005
Hair Multiplication – Aderans Research Institute (ARI) recently reported their findings
on generation of mature cycling hair follicles from skin-derived cells. ARI scientists found that "...placement of 1 million trichogenic dermal cells (2:1 ratio of dermal to epidermal cells) will result in about 200 hair follicles. This translates into the estimate of 5000 dermal cells and 2500 epidermal cells per newly formed follicle..."
Click here for details

May 02 - May 08, 2005
Hair Multiplication – Isolagen’s Skin Cell Injections to Tackle Baldness
Isolagen’s fibroblast injections may hold the key to baldness treatment. "Scientists have even succeeded in growing hair using these fibroblasts - cells which generate and control levels of the protein collagen and elastin and are found in skin, bones and other connective body tissue."
Click here for details

Apr 04 - Apr 10, 2005
Hair Multiplication – InterCytex’s Critical Proprietary Step
Are we to assume Intercytex has now overcome the DP cell-related hair cycling problems of the past previously attempted by other researchers?
Click here for details

Apr 04 - Apr 10, 2005
Hair Multiplication – Hair Multiplication – InterCytex Completed Phase I Trial
Phase I clinical trials (safety) have been completed in seven volunteers at a single UK transplant centre. No safety issues have arisen and five out of the seven patients have shown increased hair numbers. Safety studies will be followed by a multi-centre Phase II clinical trial on patients with male pattern baldness. The Phase II trial is planned for the first half of 2006 and will be performed in both the UK and North America. A Phase III trial for both male pattern baldness and female diffuse alopecia will be conducted in 2007.
Click here for details

Mar 07 - Mar 13, 2005
Hair Multiplication – Association of a polymorphism in the ornithine decarboxylase gene with male androgenetic alopecia.
”Male pattern baldness is thought to be a polygenic disorder. Which is to say that there are likely several genes involved in the development of pattern baldness. In this brand new study, researches have identified a polymorphism in the ornithine decarboxylase gene that appears to be associated with MPB. This is one more piece of the puzzle.”

Click here for details

Mar 07 - Mar 13, 2005
Hair Multiplication – Dr. Cooley on Hair Multiplication
Probably the best straightforward explanation of HM for laymen that we have seen on the net to date. Article by Dr. Cooley.
Click here for details

Mar 07 - Mar 13, 2005
Hair Multiplication – Hair Multiplication – Dr. Cooley on Hair Multiplication
Probably the best straightforward explanation of HM for laymen that we have seen on the net to date. Article by Dr. Cooley.
Click here for details

Feb 07 - Feb 13, 2005
Hair Multiplication – Dr. LU Zhongfa: “Histological Study of Reconstructed Hair Follicles”
New study by Dr. Lu Zhongfa concludes that Dermal Papilla Cells can induce hair follicle regeneration and sustain hair follicle growth in vivo and in vitro in mice.
Click here for details

Jan 31 - Feb 06, 2005
Hair Multiplication – Dr. Costarelis “Hair follicle stem cells in the lower bulge form the secondary germ, a biochemically distinct but functionally equivalent progenitor cell population, at the termination of catagen”
secondary germ, a biochemically distinct but functionally equivalent progenitor cell population, at the termination of catagen” New study by Dr. Costarelis supports the notion that keratinocytes can “dedifferentiate” to a stem cell state in response to wounding, perhaps related to signals from the stem cell niche. Finally, we also present evidence that quiescent bulge cells undergo apoptosis during follicle remodeling in catagen, indicating that a subpopulation of bulge cells is not permanent.
Click here for details

Jan 31 - Feb 06, 2005
Hair Multiplication – UWBio’s Hair Multiplication Experiment Update
Another update from UWBio on his personal Hair Multiplication experiement: “I followed Gho's procedure and I have come to the conclusion that he was not capable of getting keratinocyte growth either. If you look at the photo's he includes in his slides and in his article then you can clearly see that the cells have not even spread out, they are just circular and not in groups indicating no spread and no proliferation. I gave up on Gho's procedure and followed a procedure for isolating skin keratinocytes, but with plucked hairs.”
Click here for details

Jan 17 - Jan 23, 2005
Hair Multiplication – Interview with Dr. Lu Zhongfa of China.
Interview with an up and coming Hair Multiplication researcher from China.
Click here for details

Jan 17 - Jan 23, 2005
Hair Multiplication – Interview with Dr. Lu Zhongfa of China.
An email from InterCytex to forum members regarding Trichocyte’s trial design.
Click here for details

Jan 17 - Jan 23, 2005
Hair Multiplication – InterCytex Phase I Trial Design
An email from InterCytex to forum members regarding Trichocyte’s trial design.
Click here for details

Jan 10 - Jan 16, 2005
Hair Multiplication - “Wnt Signaling through the ß-Catenin Pathway Is Sufficient to Maintain, but Not Restore, Anagen-Phase Characteristics of Dermal Papilla Cells “
Abstract from Investigative Journal of Dermatology “Dermal papilla cells of the hair follicle can be maintained in an active, hair-inducing state in vitro when cocultured with cells secreting Wnt3a. By inducing cultured dermal papilla cells to secrete Wnt themselves, we demonstrate that this activity is a direct effect of Wnt signaling to dermal papilla cells. We further demonstrate that the effects of Wnt3a are exerted through activation of the ß-catenin signal transduction pathway and do not require alternative Wnt transduction cascades. Once dermal papilla cells have lost hair-inducing properties in vitro, neither treatment with Wnt nor expression of a truncated and activating form of ß-catenin is sufficient to restore these properties to the cultured cells.”
Click here for details

Jan 10 - Jan 16, 2005
Hair Multiplication – Farjo Medical Center’s Collaboration with InterCytex’s
Abstract from “Dermatology, Isssue #5” – “Working with Intercytex, a Manchester-based regenerative medicine company (with facilities in Boston, USA), we are seeking to restore lost hair by injecting cultured dermal papilla cells back into the scalps of the volunteers to induce the formation of functioning hair follicles to grow hair in significant numbers.”
Click here for details

Jan 10 - Jan 16, 2005
Hair Multiplication – InterCytex’s Phase I Trial in Manchester, UK
A reply from InterCytex to one of our readers “We are currently conducting a Phase I clinical trial in Manchester, UK. The investigational product, Trichocyte, is still at an early stage of development and the trial itself is purely a safety study - actual hair growth is not expected nor is it being assessed. The trial is designed only to allow injections on a very small area of the head to show that the product is safe for human use. To date, no results are available.”
Click here for details

Jan 10 - Jan 16, 2005
Hair Multiplication – Dr. Gho’s FM Procedure and the Bisection Thin Hair Study
A question has arose lately about how Gho can possible bisect the hairs in the scalp, since the thin-hair study showed that a microscope had to be used.
Click here for details

Jan 03 - Jan 09, 2005
Hair Multiplication:  Uwbio Hair Multiplication Experiment. Uwbio, one of our forum members and a scientist himself, started his own Hair Multiplication experiment a few months ago.  He just posted his most recent update with photos showing the image of a plucked hair removed from the side of his head and incubated at 37 degrees C. for 3 days.  You can still see the outer root sheath and the inner root sheath as well as the hair shaft.

Click here for details


Jan 03 - Jan 09, 2005
Hair Multiplication:  Info on the TrichoCyte (Hair Multiplication) Trials (Phase 1).  "TrichoCyte is made from a sall sample of scalp tissue from a hairy part of your head.  The biopsy is taken under local anaesthetic and can measure approximately 0.5cm2 to 2cm2 in area depending on your hair density.  The skin is processed in the laboratories at Intercytex Ltd to form a suspension of DP cells.  The manufacturing process takes approximately 4 weeks.  The DP cells will then be injected back into a small balding area on your head (under local anaesthetic).”

Dec 27 - Jan 05, 2005
Hair Multiplication – Dr. Fuch’s Self Renewal, Multipotency, Stem Cell Research
The latest research publication by Dr. Fuchs et al on self renewal and multipotency in skin stem cells.
Click here for details

Dec 27 - Jan 05, 2005
Hair Multiplication – Bisection Techniques
A discussion about using bisection technique in Hair Multiplication with references to research done in this area. Pictures of Dr. Gho’s Follicular Multiplication technique can be found in this discussion too.
Click here for details

Dec 27 - Jan 05, 2005
Hair Multiplication – Dr. Washenik’s interview with WebMD about Hair Multiplication
"According to Dr. Wasehnik, while Hair Multiplication is still 3-4 years away, the concept of tissue-engineered hair growth to create a new hair organ looks very real.

Click here for details

Dec 27 - Jan 05, 2005
Hair Multiplication – Intercytex’s Trichocyte phase 1 trial volunteer info sheet
""TrichoCyte is made from a small sample of scalp tissue from a hairy part of your head. The biopsy is taken under local anaesthetic and can measure approximately 0.5cm2 to 2cm2 in area depending on your hair density. The skin is processed in the laboratories at Intercytex Ltd to form a suspension of DP cells. The manufacturing process takes approximately 4 weeks. The DP cells will then be injected back into a small balding area on your head (under local anaesthetic). Strict procedures are in place to ensure that the TrichoCyte made from your skin samples will only be used to treat you. 50 - 100 injections will be applied, each containing 1 micro litre (very small volume) of cells.”

Click here for details

Dec 06 - Dec 12, 2004
Hair Multiplication:  Dr. Bazan’s November 2004 Hair Multiplication Update.  Thanks to Bender in the Hair Multiplication forum, we have the lastest update from Dr. Bazan on his Hair Multiplication research. A total of 28 questions have been answered.  Click here to read the Q&A with Dr. Bazan.

Dec 06 - Dec 12, 2004
Hair Multiplication:  Surprising report on human hair cloning comes from China.  “Previously unknown group of Dr. Zheng Men from china independently from the more proclaimed scientists and hair transplantation clinics from US and Europe conducted human hair cloning experiments.  They used a technique of combining and transplanting various cell types of the hair follicle from humans to induce new hair growth. This, in principle, it is identical to the methods of hair cloning pursued by Ken Washenik and his colleagues from the Bosley Medical.”

Oct 25 - Oct 31, 2004
Hair Multiplication: Stem Cells Research - Elaine Fuchs (Ph.D.) did it again ! Stem Cells Renew Hope for Fading Hair Follicles. Howard Huges Medical Institute (HHMI) researchers discover that stem cells isolated from the skin of mice can self-renew and differentiate into skin and functioning hair follicles. The studies suggest that the human equivalent of these stem cells -- which researchers are currently trying to isolate -- could be used to regenerate skin and hair. Research published in the September 03, 2004, issue of Cell. HHMI  investigator(s): Elaine Fuchs, Ph.D., The Rockefeller University

Oct 18 - Oct 24, 2004
Hair Multiplication: HairSite's forum member HM experiment. Tired of waiting for Hair Multiplication researchers to come up with the goods? Check out long time forum member UWBio's personal experiment with Hair Multiplication. Note: not for the amateurs. UWBio works in the biology & medical research field.

Aug 16 - Aug 22, 2004
Hair Multiplication
: Harvard Hair Research "Dermal Papilla-Induced Hair Differentiation of Adult Epithelial Stem Cells from Human Skin". 

Aug 09 - Aug 15, 2004
Hair Multiplication: Dr. Cole's new study looking at the follicular sheath for evidence of stem cells.

Aug 02 - Aug 08, 2004
Hair Multiplication: Dr. Gho answered forum member TK421's questions about hair multiplication.

Aug 02 - Aug 08, 2004
Hair Multiplication: Intercytex looking for volunteers for their TrichoCyte hair multiplication project.

Jul 19 - Jul 25, 2004
Hair Multiplication: Chinese researchers showed that hair follicle-like structure is generated in vivo when the mixed cells of early passages cultured hair papilla cells with hair follicle epithelium are implanted into the subcutis of nude mice. Department of Dermatology, the Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310009, China.

Jun 28 - Jul 04, 2004
Hair Multiplication: Dr. Stenn (Aderans)'s latest patent application: compositions and methods for inducing new hair follicle formation and hair growth in a desired orientation. New discovery showing that formation or regeneration of a hair follicle can be induced by contacting the epidermal tissue with certain growth factors in the absence of added papilla cells. October 23, 2003. 
 

Jun 14 - Jun 20, 2004
Hair Multiplication: World's first Hair Multiplication brochure "leaked" to the public by GHO Clinic's staff in Madrid, Spain.

Jun 14 - Jun 20, 2004
Hair Multiplication: Dr. Bazan answered our follow up questions with the latest update on his protocols release date as well as a hint about a possible collaboration with an Ivy League university in the United States.

Jun 14 - Jun 20, 2004
Hair Multiplication & Hair Transplant: 4 remarkable discoveries about Dr. Gho's Follicular Multiplication procedure.  

Jun 14 - Jun 20, 2004
Hair Multiplication: Dr. Gho's research paper on Hair Multiplication and Follicular Multiplication featured in the highly respected British Journal of Dermatology. 

May 17 - May 23, 2004
Hair Multiplication:
Part II of our Q&A with Dr. Bazan regarding Scalp Impregnation Therapy and Dermal Papilla Hair Multiplication procedures. 

May 10 - May 16, 2004
Hair Multiplication:
Latest update from Dr. Washenik on Intercytex, Bosley and Aderans.  

May 03 - May 09, 2004
Hair Multiplication:
Latest update from Dr. Washenik on Intercytex, Bosley and Aderans.  

Apr 26 - May 02, 2004
Hair Multiplication:
Bosley Medical to join force with Intercytex. 

Feb 02 - Feb 08, 2004
Hair Multiplication & Hair Transplant:
Gho Clinic invites you to a 1 day seminar in Orlando & Miami on Follicle Transplantation and Hair Multiplication. Feb 21 & 22, 2004. Click here for the location and time of the event. 

Jan 26 - Feb 01, 2004
Hair Multiplication:
Dr. Bazan's Hair Multiplication & Scalp Impregnation Therapy information request form now available online.

Jan 19 - Jan 25, 2004
Hair Multiplication:
World's first hair multiplication photo goes live on the internet, courtesy of Bazan Institute.

Jan 12 - Jan 18, 2004
Hair Multiplication:
World's most anticipated news in surgical hair restoration advancements - Dr. Carl Bazan (Mexico) to introduce Hair Multiplication in 2004. 


Dec 22 - Dec 28, 2003
Hair Multiplication:
WIRED magazine Jan 2004 issue talks about Hair Multiplication, with references to Dr. Cooley, Dr. Jahoda and Dr. Washenik.
(email hairsite@aol.com if link no longer active).

Dec 22 - Dec 28, 2003
Hair Multiplication:
Dr. Jahoda's latest research - cell movement in the Hair Follicle Dermis: more than a two-way street?

Dec 15 - Dec 21, 2003
Hair Multiplication: Intercytex discussed on Spencer's show, summary courtesy of Ahab in the forum.  

Dec 15 - Dec 21, 2003
Hair Multiplication: New patent application by Dr. Stenn, Aderans, October 2003. Compositions and methods for inducing new hair follicle formation and hair growth in a desired orientation. 

Dec 15 - Dec 21, 2003
Hair Multiplication: Intercytex Aug 2003 patent application - Cell delivery system, a method for inducing organ or tissue formation by delivering inductive cells into an organ or tissue regenerative cellular environment using a controlled delivery device. For the regeneration of hair, the method includes inducing hair follicle formation by delivering inductive cells into a dermal layer using a controlled delivery device. 

Dec 15 - Dec 21, 2003
Hair Multiplication: Intercytex letter to forum member AIO regarding human trials.   

Dec 08 - Dec 14, 2003
Hair Multiplication: Aderans' new patent application, April 2003 - methods for inducing new hair follicle formation and hair growth in a desired orientation - April 2003.

Nov 10 - Nov 16, 2003
Hair Multiplication & Hair Transplant
: Interview with Dr. Bazan: Scalp Impregnation Therapy & Follicular Unit Extraction hair transplant. 

Oct 13 - Oct 19, 2003
Hair Multiplication
: Abstract of Dr. Gho's Hair Multiplication and Follicle Transplantation presentation at the 11th annual scientific meeting of the International Society of Hair Restoration Surgery. 

Sep 01 - Sep 07, 2003
Hair Multiplication
: Q&A with Dr. Cole about his Hair Multiplication experiment. 

Sep 01 - Sep 07, 2003
Hair Multiplication
: Dr. Cole started Hair Multiplication experiement. Click here for photos and discussions.